Shared Flashcard Set

Details

Ophtho/Derm/Rheum-Path
Soft-tissue Tumors/Tumor Like Lesions
19
Pathology
Graduate
11/30/2010

Additional Pathology Flashcards

 


 

Cards

Term
What are the common fibrous growths
Definition

Fibroma: Dematofibroma, Recurrant Infantile Digital Fibroma, Fibroma Molle

Fibromatosis(Desmoid Tumors)

Dermatos Fibrosarcoma protuberans

Fibrosarcoma

 

Term
Which fibromatous lesions have a high recurrance rate?
Definition

Fibrosarcoma

Fibromatosis

Recurrent Infantile Digital Fibroma

Term
What fibrous growths exhibit a storiform
Definition

Pleomorphic Fibrous Histiocytoma

Dermatos Fibrosarcoma protuberans

Dermatofibroma

Term
What is the histology of a fibrosarcoma and its most likely site
Definition

Herringbone Pattern

Deep CT in the limb of an adult

Term
What is the most common soft tissue tumor
Definition
Lipoma
Term
What are the different types of lipomas and key points of each
Definition

Infiltrating: infiltrate muscle, Thigh, Shoulder

Spindle Cell: head and neck of elder Men

Pleomorphic: Atypical Nuclei "Floret Cells"

Angiolipoma: Pain, with microthrombi

Lipoblastoma: myxoid, affecting children

Hibernoma: Brown Fat

Term
Most common sites for lipomas
Definition
neck, shoulder, arm, and trunk
Term
What are the different types of Liposarcoma and which is the most common and which has the best prognosis
Definition

Well Diferentiated: Lipoma-Like or  Sclerosing

Myxoid: best prognosis, most common, Chicken wire vessels (Plexiform)

Round Cell

Pleomorphic: Giant cells, Lipoblasts, spindle

Term
What histology distinguishes a malignant Pleomorphic Fibrous Histiocytoma from a Dermatos Fibosarcoma Protuberans and from the benign form of the Pleomorphic Fibrous histiocytoma?
Definition

Pleomorphic Fibrous Histiocytoma: Storiform pattern with fibroblastic and histiocytic cells with tumor giant cells

Dermatos Fibrosarcoma Protuberans lacks Giant cells

The benign form lacks a storiform pattern

Term
What are the characteristics of a leiomyoma
Definition

Able to be Shelled-Out

Subcutaneous are Painful

Some are Vascular or Epithelioid

Spindle Cells with blunt nuclear ends

Term
What is more common leiomyoma or leiomyosarcoma and what characteristics are more indicative of malignancy
Definition

Leiomyoma is more common

Necrosis/Hemorrhage

Hypercellular

Pleomorphic

Term
What is the most common soft tissue tumor in children?
Definition
Rhabdomyosarcoma
Term
What disease is rhabdomyoma associated with
Definition
Tuberous Sclerosis
Term
What are the different types of Rhabdomyosarcoma, their age group and common locations
Definition

Embryonal(<5 yrs old)

Sarcoma botyroides(grape like) under Mucosal membrane, Head, Neck, UGT, Biliary, Retroperitoneum

Alveolar 10-25 yrs old, Extremities

Pleomorphic Adults

Term
What is an hemangioma and where is it likely to be found
Definition
Vessel tumor present at birth in the head or neck
Term
What are the malignant vascular tumors and what are key characteristics of each
Definition

Angiosarcoma- head and Neck of Elderly

Lympangiosarcoma-Arise in long standing lymphedema(Stewart-Treves Syndrome= Lympangiosarcoma after mastectomy)

Karposi's Sarcoma- Slit like vascular space containing erythrocytes from herpes virus seen in AIDS patients

Term
Decribe the appearance of each of the fibrous tumors
Definition

Dermatofibroma: Redish-Brown,Storiform, Capillaries, Histiocytes

RecurrantIDF: Subcut and dermis

Fibroma Molle: Mature Fibrous and Fat Tissue

Fibromatosis: Local invasion, abundant collagen

DermatosFSP: Polypoid, Storiform, Subcut

Fibrosarcoma: Herringbone

Term
What syndromes are associated with Multiple Lipomas?
Definition

Neurofibromatosis

Multiple Endocrine Adenoma Syndrome

Term
What patient and what location does a synovial sarcoma typically present in?
Definition

Young Adult

Ankle or Knee

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