Term
| What are some commonly shared signs of all the spondyloarthrities? |
|
Definition
Dactylitis
Sacroilitis
Ocular Inflamation
Bowel Inflamation |
|
|
Term
| What is the epidemiology of Ankylosing Spondylitis |
|
Definition
Males
<45
Familial
6.4% of all people that are HLA-B27 |
|
|
Term
| Clinical features and complications of Ankylosing Spondylitis |
|
Definition
Lower Back Pain:Ascend from Lumbar
Sacroilitis->Fusion
Squaring Vertebrae
Syndesmophyte Formation
Cauda Equine Syndrome
EYE: Uveitis
CV: Heart Block/Aortic Insufficiency
Pulm: Pulmonary Fibrosis
|
|
|
Term
| Diagnosis of Ankylosing Spondylitis |
|
Definition
Flattening Lumbar Kyphosis
Shoeber Manuever
X-Ray: Sacroilitis/Squaring Vertebrae
CRP, HLA-B27 |
|
|
Term
| What is the prognosis of ankylosing spondylitis |
|
Definition
Progressive Stiffness-> Lost ROM-> Disability
Fusion can improve pain
|
|
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Term
| What is the precipatating factor for reactive arthritis? |
|
Definition
Typically infection of the Urethra or GI Tract:
Urethra: Chlamydia trachomatis
Dysentrary: Shigella, Salmonella, Yersina, Campylobacter fetus |
|
|
Term
| When infection route is more likely to precipatate reactive arthritis in men |
|
Definition
After an urethral infection
Equal incidence in dysentary |
|
|
Term
| What are the common clinical features of reactive arthritis? |
|
Definition
Triad: Conjunctivitis, Urethritis (from infection and dysentary), Arthritis(Assymetric lower limbs)
Mouth Ulcers
Keratodermia Blennorhagicum-Psoriasis on soles
Circinate balanitis: uncircumcised-shallow ulcer, circumcised- hyperkeratotic lesion on glans
|
|
|
Term
| Prognosis of Reactive Arthritis |
|
Definition
May Recur
If becomes Chronic disease: Spondylitis, AS heart lesions(Heart Block/Aortic Insufficiency) |
|
|
Term
| What symptom usually presents first in psoriatic arthritis |
|
Definition
|
|
Term
| What are the typical clinical features of psoriatic arthritis and are the serious complications |
|
Definition
Asymetric arthritis
DIP arthritis with same nail involvement
Sausage finger
Compications: Arthritis Mutilans-Pencil in cup
Spondlitis of DIP |
|
|
Term
| Does the psoriasis and the arthritis of psoriatic arthritis share a common mechanism? |
|
Definition
| Nope. HSCT will transfer the colitis between animals not the Arthritis |
|
|
Term
| What is enteropathic arthopathy and are both symptoms concurrent? |
|
Definition
Arthropathy associated with Crohn's disease or Ulcerative colitis
The two manifestations are independent but arthropathies tend to increase during bowel flares |
|
|
Term
| What classifies a disease as an undifferentiated Spondyloarthritis |
|
Definition
| Isolated and subclinical manifestations of the major arthritities |
|
|
Term
| what symptoms is the B-27 allele most closely associated with |
|
Definition
|
|
Term
| What is the treatment for spondyloarthropathies |
|
Definition
NSAID
TNF blocker
Antibiotics for Reactive |
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