Term
| what is the most legitimate human subject experimentation |
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Definition
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Term
| what is the most dubious human subject experimentation |
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Definition
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Term
| what is the most dangerous human subject experimentation |
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Definition
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Term
| describe benefience in regards to human experimentation |
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Definition
| do not harm. maximize possible benifits, minimize possible harm |
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Term
| what is justuce in regards to human experimentation (also give examples) |
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Definition
| fairness in treatment (including haves and have nots), equality in distribution (randomization of placebos) |
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Term
| what is an injustice when related to human subject experimentation |
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Definition
| when a benefit entitled is denied without reason when some burden is imposed unduly |
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Term
| when doing human subject experimentation wat is required |
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Definition
| independent review, vaildity and value in research purpose and design, minimize risk, maxamize safety, fully inform each subect or authorized representitive, disclose any conflicts of interest, HIPAA authorization |
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Term
| what is the fundimental principal in regards to human subject experimentation |
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Definition
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Term
| what is the definition of a human subject |
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Definition
| living indivigual whom a research investigator obtains data through intervention or interaction with the individual or from individually identifiable information |
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Term
| what is the definition of intervention |
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Definition
| manipulation of the subject or the subject's enivornment |
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Term
| what is the definition of private information and an example |
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Definition
| interpersonal contact between investigator and subject (physical exam) |
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Term
| what is the definition of identifiable information (give examples) |
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Definition
| identity of the subject can be ascentained by the investigator or information associated with the subject (assigning a number, specific demographic) |
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Term
| when are placebo controlls allowed |
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Definition
| when scientifically or methodological reason, when study adresses a minor condition and the patient's recieving will not be subject to additional risk or irreversible harm |
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Term
| how can you make sure your medical therapy human subject experimentation is in the best interest of the patient and all risks have been considered |
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Definition
| appreach with peers, institutional review board, and other expert groups |
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Term
| what does it mean when it is said that psychological research is more dubious |
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Definition
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Term
| what is the difference between medical and biological research |
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Definition
| biological is more dangerous, medical is more ledegitamite and less invasive |
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Term
| describe respect in regards to human subjects |
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Definition
| subject must have the capacity to represent their own interest and free to say stop treatment, make sure not to exploit people, make sure people who are volurnable are protected, make sure subject is willing and there are no hidden contingencies (like prisoners have) |
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Term
| what does it mean when said that human subject research must be valid and valuable |
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Definition
| degree to which the research measures what it says it will, can be repeated with consistancy, able to be generalized for many populations, outcome improves treatment or prepares to improve it |
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Term
| what are the types of human subject research |
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Definition
| intervention, private information, identifiable information |
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Term
| describe the Joseph Memgle studies |
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Definition
| twin studies done by Nazis, injected blue dye to change eye color, forced male and female twins to reproduct, exchanged blood between twins, boiled bodies to preserve hunch back father and son |
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Term
| describe the Tuskege research |
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Definition
| men REPORTEDLY had LATENT syphillis, poor black men told they were being treated but ~200 were not treated at all, given meals and culturally sensitive mathods (funeral money) as incentives, NOT injected with syphillis, |
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Term
| who put on the tuskege research and when |
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Definition
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Term
| why does the year the tuskege research started cause alarm |
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Definition
| because a syphilis treatment was found in 1930 and was not offered to the subjects, it was kind of dangerous but worked |
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Term
| what was the second point in time during the tuskege research that caused alarm |
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Definition
| in 1943 penicillin was found to be a safer way to treat syphillis but they did not give the subjects the option to take it and gave them incentives not to |
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Term
| who lead the fight against the tuskege research, describe the story how |
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Definition
| Peter Buxton spoke with a subject and was concerned he was not getting penicillin, he wrote the CDC and they had a comittee meeting that said the research was once in a life time and must be continued, his GF wrote about it in the newspaper and another comittee viewed it as fine before penicillin but not ok now, congress made laws against bad research in result |
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Term
| describe the harvard case |
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Definition
| research was whistle blower and showed reliability and validity issues and altered data, it was moved from lower to circut cort and is still in trial |
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Term
what is a key point in regards to human research:
A. respect, harm, care
B. justice, humanity, truth
C. cecil, herbert, sinfield
D. respect, benifience, justice |
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Definition
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Term
research should be reviewed by"
A. experts and the IRB
B. no one
C. only in limited circumstances |
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Definition
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Term
what does the picture of soldiers represent:
A. troops exposed to TNT
B. radiation experiments
C. troops watching experiments
D. troops exposed to agent organge |
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Definition
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