| Term 
 | Definition 
 
        | most potent cycloplegic agent can last up to 2 weeks
 used when long term dilation is necessary (ie very bad iritis, or eveitis, post-op)
 decreases intraocular inflammation
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        |  | 
        
        | Term 
 | Definition 
 
        | fastest acting cycloplegic agent (30 min) shortest duration of ation: 4-6 hrs
 uses: refractions (OK in children), dilated fundus exams, used by itself or w/phenylephrine for routine dilation
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        |  | 
        
        | Term 
 | Definition 
 
        | cycloplegic agent, stronger than mydriacyl acts in 30 min, lasts up to 24 hrs
 Uses: children to determine acute refraction correction, corneal abrasion, mild conditions to keep eye relaxed for a few days or to decrease pain
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | cycloplegic agent lasts 1-3 days
 uses: 4x/day for corneal abrasions, chemical burns to eye, iritis, uveitis, post-op
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | cycloplegic agent lasts 2-4 days to 1 week
 NOT used on a regular basis b/c of AE but used as transderm patch to prevent motion sickness (may cause unilateral pupil dilation)
 AE: greater incidence of toxic rxn than any of the other drugs: psychosis, restlestness, confusion, hallucinations, vomiting, urinary incontience
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        | Term 
 
        | What cycloplegic agents can be used to increase patient comfort with corneal abrasions? |  | Definition 
 | 
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        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | adrenergic agonist, stimulators mueller's muscles and dilator muscles dilation seen in 45 min, recovery in 6 hours
 usually added to over the counter drops, whiten the eye due to vasoconstriction
 rebound effects: vasodilation, eye redeness
 |  | 
        |  | 
        
        | Term 
 
        | What is the fastest acting pupil dilator? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What is the drug of choice for routine dilation? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What are the cycloplegic agents, and how do they work? |  | Definition 
 
        | atropine, mydriacyl, cyclogyl, homatropine, scopolamine they are cholinergic antagonists that block constriction and accomodation
 |  | 
        |  | 
        
        | Term 
 
        | alpha adrenergic receptors on the eye |  | Definition 
 
        | cause contraction of radially arranged dilator muscles in the iris--> pupil dilation |  | 
        |  | 
        
        | Term 
 
        | cholinergic receptors on the eye |  | Definition 
 
        | sphincter muscle in iris (constrict pupil) and ciliary muscles (near accomodation) |  | 
        |  | 
        
        | Term 
 
        | B adrenergic receptors in eye |  | Definition 
 
        | ciliary body: relax-> far accomodation |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | direct-acting cholinergic agonist used to test for anisocoria
 contracts and pulls iris in>stretches trabecular meshwork>^aq humor drainage>decrease intraocular pressure
 |  | 
        |  | 
        
        | Term 
 
        | What drug can cause a brow ache in patients, and why? |  | Definition 
 
        | pilocarpine decreases amount of light into eye and ability to accommodate
 |  | 
        |  | 
        
        | Term 
 
        | What are the AEs of pilocarpine? |  | Definition 
 
        | brow ache pupillary constriction
 spasm of accomodation
 |  | 
        |  | 
        
        | Term 
 
        | What is the MOA of epinephrine? |  | Definition 
 
        | acts on receptors in trabecular meshwork to increase fluid outflow and therefore decrease intraocular pressure |  | 
        |  | 
        
        | Term 
 
        | What are the AEs of epinephrine? |  | Definition 
 
        | HTN crisis & tachycardia via nasal absorption localized burning, irritation, allergic rxn, accum of melanin granules, redness of eyes, headache
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | more lipophilic version of Epinephrine> increased absorption into cornea>less systemic AEs and lower concentration needed |  | 
        |  | 
        
        | Term 
 
        | What is the drug of choice for glaucoma? |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | non-selective beta blocker used for glaucoma moa: decreases aqueous formation via receptors on ciliary bodies
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | selective B1 blocker decreases aqueous formation
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | alpha-adrenergic agonist, decreases aqueous formation |  | 
        |  | 
        
        | Term 
 
        | How do you diagnose Horner's syndrome? |  | Definition 
 
        | block NE reuptake (ie cocaine) (no dilation = horner's)
 light reflex test (turn off light, size diff bet pupil increase = Horner's
 |  | 
        |  | 
        
        | Term 
 
        | How do you test a patient to see if a 3rd order neuron defect is causing Horner's? |  | Definition 
 
        | paredrine stimulates 3rd order neuron (no dilation = 3rd order neuron defect) |  | 
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