Term
| What is the most dangerous/destructive form of arthritis? |
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Definition
non-gonococcal bacterial infection
cartilage and joint can be destroyed rapidly
30% have residual pain and decreased ROM after treatment
mostly monoarticular
polyarticular in patients with pre-existing polyarticular arthritis or IV drug users |
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Term
| How is an infection of a joint diagnosed? |
|
Definition
| purulant synovial fluid: 50-100K WBCs/mm, >90% PMNs |
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Term
| How is a joint infection treated? |
|
Definition
parenteral antibiotics for more than 2 weeks (4-6 if S aureus or GNR)
gram (+): vanco initially
gram (-): ceftaz +/- aminoglycoside
serial drainage
surgery if persistent, prosthetic joint, or poor access |
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Term
| What are the causes of a joint infection? |
|
Definition
dissem gonococcal infection
fungal, mycobact, viral
lyme disease
non-gonococcal bacteria |
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Term
|
Definition
causd by precip of urate crystals
acute gouty arthritis
urate urolithiasis
tophi
intercritical gout |
|
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Term
| Causes of hyperuricemia (>7mg in men, >6mg in women) |
|
Definition
overproduction:
1: idiopathic
2: myeloprolif disorders, drugs, enzyme defects
underexcretion:
1: unknown
2: renal defect/failure |
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Term
|
Definition
Ca Pyrophosphate Dihydrate Crystal deposition
mono or oligoarticular
arthritis that mimics gout
associated with chondrocalicnosis
typically >65y0 |
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Term
| How is gouty arthritis diagnosed? |
|
Definition
inflamm peaks in 3 hrs, lasts 2-3 weeks
tophi are not inflamed, and appear late
urate crystals= diagnostic
negative birefringence |
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Term
| List the order of increasing WBCS in synovial fluid for each condition |
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Definition
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