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OBGYN Fetal Growth Abnormalities
KYCOM Block 13
56
Medical
Graduate
01/18/2014

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Cards

Term
what is the best way to get the best gestational age
Definition
see mom as soon as possible to the conception
Term
what is neagele's rule
Definition
subtract 3mo from FDLMP and add 7 days to get gestational age
pregnancy duration is 280d +/- 14d
Term
how often is a pregnancy on the expected delivery day, how often within 14d
Definition
5% on day
60% within 14d
Term
what are the 6 best estimates of gestation dating in order from best to least
Definition
1. last menstural period
2. uterine size (early gestation and umbilicus)
3. audible fetal heart size
4. fundal height (late gestation)
5. quickening (first perception of fetal movement)
6. positive pregnancy test
Term
where is the fundus at 20wks
Definition
at height of umbilicus
Term
where is the fundus at >16wks
Definition
approx 1cm/wk measured from the pubic symphysis

EX: 34 wks gestation should be 34cm from symphysis
Term
what is the accepted discrepency for fundus height
Definition
>4cm should alert doc of problem (in reality it is 2-3cm)
Term
what are the ultrasound baby measurements 7
Definition
BPD
HC
AC
HC/AC
HC/TC
EFW
FL
Term
what is BPD
Definition
bi-parietal diameter
Term
what is HC
Definition
head circumference
Term
what is AC
Definition
abdominal circumference
Term
what is HC/AC
Definition
head circumference/abd circumference ratio
Term
what is HC/TC
Definition
head circumference/ thorax circumference ratio
Term
what is EFW
Definition
estimated fetal weight
Term
what is FL
Definition
femur length
Term
definie low, very low, and large birth weight, what is the prevelence, what is another name for large
Definition
<2500g: low 8%
<1500g: very low 2%
>4000g: large (macrosomia) 10%
Term
what is IUGR
Definition
FETUS whose weight is <10th percentile at given gestational age
Term
what is SGA
Definition
NEONATE whose birth weight is at or below the 10th percentile at gestational age
Term
what is LGA
Definition
NEONATE whose birth weight is >90th percentile at gestational age
Term
what are the two fetal growth types, define each
Definition
early: hyperplastic: increase in cell number

late; hypertrophic: increase in cell size
Term
symmetric growth: onset, cell number, BPD/HC, HC/AC, diminution
Definition
onset: early
cell number: decreased
BPD/HC:small
HC/AC: normal
diminution: irreversible diminituion of organ size and function
Term
asymmetric growth: onset, cell number, BPD/HC, HC/AC, diminution
Definition
onset: late
cell number: decreased
BPD/HC: normal
HC/AC: increased
diminution: amendableto restoration of size and function of organs with adequate nutrition
Term
what is the most important measurement in determine symmetric and asymmetric fetal growth
Definition
HC/AC
Term
what is the #1 and #2 cause pf perinatal mortality
Definition
1. preterm
2. IUGR
Term
mortality rate for IUGR: compared to normal babies, with corrected anomalies, without corrected anomalies
Definition
normal compare: 7-10% increase
corrected: 100/1000
not corrected: 120/1000
Term
what causes morbidity in IUGR babies 9
Definition
asphyxia
hypoglycemia
hypocalcemia
hypothermia
meconium aspiration
polycythemia/hyperviscosity syndrome
congenital anomalies
congenital infection
pulmonary hemorrhage
Term
maternal causes of IUGR 9
Definition
drugs
smoking
malnutrition
alcohol
DM
CT disease
pregnacy weight <50kg
chronic HTN (25-30%!!)
chronic maternal disease: cyanotic heart disease)
Term
fetal causes of IUGR 3
Definition
infection: viral, protozoal <5%
genetic and chromosome disorders 15%
congenital abnormalities
Term
urterine/placental causes of IUGR 5
Definition
placental abruptions
placenta previa
multiple gestation
mullerian anomalies
marginal cord insertion
Term
what is the most common maternal factor associated with IUGR
Definition
hypertension
chronic (pregestational) or PIH
25-30%!!
Term
how is IUGR diagnosed 5
Definition
acurate and early dating and recording
EARLIEST ULTRASOUND IS MOST ACURATE
NEVER change estimated delivery date based on follow-up ultrasound!

physical exam - fundus height
ultrasound parameters
doppler studies S/D ratio
percutaneous umbilical cord sampling
Term
how does an untrasound S/D ratio help diagnose IUGR
Definition
as placental resistance increases, diastolic flow decreases
Term
what is the information obtained from percutaneous umbilical cord sampling 5
Definition
rapid karyotyping
congenital infection
hematologic parameters
nutrition
fetal blood gas
Term
we get awesome info from percutaneous umbilical cord sampling, why dont we do it on all babies
Definition
risk 1-3%
Term
management of IUGR antepartum
Definition
estimate cause
bed rest
fetal movement counting
serial sonography
NST: CST, BPP
doppler ultrasound
amniocentesis maturity studies
PUBS
Term
what does PUBS stand for
Definition
percutaneous umbilical cord sampling
Term
management of IUGR intrapartum
Definition
electronic fetal monitoring
preparation for C section: amnionfusion
oxygen therapy
neonatal/anesthesia consultation
Term
management of IUGR post partum
Definition
pharyngeal suction
neonatal recussitation if needed
avoid hypoglycemia (decreased fat stores)
avoid hypothermia: O2 therapy
avoid hyperviscosity syndtome
Term
hyperviscosity syndrome: qualification, initial issue, 3 effects
Definition
HCT>65%
polycythemia causes multiorgan thrombosis, heart failure, hyperbilirubinemia
Term
after birth of a IUGR baby what should be expected in their development 4
Definition
most catch up early on in growth (25% remain in <10th percentile through childhood)

at risk for neurological abnormalities

50% have learning dissability

brain sparing type: normal HC, associated with decreased neurological signs
Term
what is the risk of having multiple IUGR babies
Definition
25% for subsequent pregnancies
after 2 IUGR pregnancies risk x4
rest is associated to the contributing factor for IUGR
Term
how can IUGR be prevented in a high risk mom (2)
Definition
aspirin and dipyridamole
effective in a few small studies
Term
what is fetal macrosomia
Definition
>90th percentile at given gestational age (>4000-45000g)
Term
cause of macrosomia (physiology in baby) 2
Definition
hyperinsulinemia
increased insulin like growth factors
Term
how does hyperinsulinemia in baby cause macrosomia 3
Definition
increased lipogenesis
increased glycogen synthesis
increased protein
Term
causes of macrosomia by mom 3
Definition
obesity
diabetes
excessive weight gain
Term
outcomes in macrosomia in baby 4
Definition
birth trauma
asyphxia
still birth
neurological damage
Term
management of macrosomia 3
Definition
control gestational DM
prepare for prolonged labor (esp descent) and C section
Term
when should a C section be done on a baby with macrosomia
Definition
>5000g without DM
>4500g with DM
Term
define shoulder dystocia
Definition
impaction of fetal shoulder behind maternal pubic symphysis
Term
risk factors for shoulder dystonia 6
Definition
DM!!!!!
post-date (42wk+)
male fetus is larger
maternal obesity
second stage labor disorders
use of vaccume/forceps
Term
complications of shoulder dystonia and prevelence
Definition
brachial plexus injury 95% of time
0.3-1% irreversible
Term
what does an irreversible brachial plexus injury cause
Definition
erbs palsy (C5-6)
Term
what is the incidence of brachial plexus injury by weight of baby
Definition
>4000g 10%
>4500g 20-30%
<4000g 50%!!!
Term
manuvers to help get baby with shoulder dystocia out 7
Definition
suprapubic pressure: nurse pushes down
McRoberts: exaggerated flexion of thighs on mom
episotomy
delivery of posterior shoulder: usually works
rubins/corkscrew: rotation
zavanelli
Term
what is a zavanelli
Definition
push baby with shoulder dystonia back in and do emergency C section
high mortality rate
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