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OB/GYN Clinical year
n/a
184
Medical
Graduate
06/16/2012

Additional Medical Flashcards

 


 

Cards

Term
Embryologic structures:

1. in males: ducts that persist under testosterone as genital ducts - epididymis, ductus deferens, ejaculatory duct. in females: degenerate - remnants may persist as broad ligament. in both sexes - help to form the ureter, pelvis, calices, and collecting tubules

2. in males: regression occurs due to antimullerian hormone from sertoli cells - forms appendix testis. in females: differentiation produces uterine tubes, uterus, vaginal wall

3. plays important role in early embryonic circulation, site of primordial germ cells

4. forms at 5th week, midportion of each urogenital ridge thickens as cellular condensation forms this. lacks either testicular or ovarian morphology until 7th week

5. progenitor of urinary bladder, urethra, vagina, and other genitalia

6. gives rise to urogenital system
Definition

1. mesonephric ducts (wolffian)

2. paramesonephric (mullerian) duct

3. yolk sac

4. gonadal ridge

5. urogenital sinus

6. urogenital ridge

Term
C-Section

1. abdominal incision
2. uterine incision used for previa, transverse lie, preterm delivery, or fetal distress. is the most rapid option. associated with greater blood loss and increased change of uterine rupture in subsequent pregnancies
3. uterine incision associated wtih less blood loss and risk of uterine rupture
4. indications?
5. complications
Definition

1. incision: transverse abdominal most common, others: midline suprapubic

2. classical vertical incision

3. low-transverse incision

4. indications: when vag delivery is not feasible or would impose undue risk, repeat c/s, cephalopelvic disproportion/dystocia, malposition/presentation, fetal distress, placenta previa, preeclampsia, multiple gestation, fetal abnormalities, cervical cancer, active herpes

5. complications: pospartum hemorrhage, endometritis, wound infection, dehiscence

Term
Hysterectomy - 2nd most common major operation performed in US
1. indications
2. pre-op work up
3. indications for TAH
4. indicaitons for supracervical
5. indicaitons for vaginal
6. indications for LAVH
7. indications for hysterectomy after c/s
Definition

1. indications: tx of gynecological cancer, benign gyn conditions, obstetrical complications

2. pre-op: baseline eval to detect cancer - pap smear w/in 3 mos, bimanual exam, pelvic US, IVP, bowel prep, IV abx before procedure, compression stockings for VTE pro

3. TAH: sx or pelvic findings suggesting adnexal disease, older pts with significant GI complaints, pts wanting additional procedures (liposuction)

4. Supracervical: difficulty dissecting cervix, distorted atatomy due to PID or endometriosis, compromised medical condition. less chance of nerve damage and therefore bladder/orgasmic problems

5. vaginal: gynecoid pelvis w/ wide pubic arch and vaginal apex >2 fingerbreadths, uterine size <280g, significant heart/lung disease

6. LAVH: decreased length of hospital stay, decreased postop analgesia, decrased convalescence, lower complications

7. after c/s: hemorrhage, abnormal placental implantation, uterine atony, inability to repair ruptured uterus, large myomas

Term
Endometriosis:

1. definition
2. s/s
3. most common site?
4. key words
5. complications
6. treatment
Definition

1. abnormal grwoth of uterine tissue in places other than uterine lining. found almost exclusively in women of reproductive age

2. s/s: red petechial lesions on peritoneal surfaces of pelvic organs - dark brown/blue/black in appearance, pelvic pain during menstrual cycle, infertility, dysmenorrhea, dyspareunia, pelvic pain, premenstrual spotting, uterine motion pain, tender adnexa, abnormal uterine position

3. ovary

4. "choclate cysts", "powder burns"

5. complications: catamenial pneumothorax

6. treatment: expectant management, analgesia, OCPs, progestins, GnRH agonists, aromatase inhibitors, surgery, IVF

Term
cysts containing well differentiated tissues derived from any 3 germ layers: hair, teeth, ectoderm.

s/s: usually asymptomatic unless torsion or rupture

dx: transvaginal US

tx: laparoscopic removal
Definition
cystic teratoma/dermoid
Term
most common malignant tumor of the ovary
an epithelial cancer

85% associated with extraovarian spread at time of dx
Definition
serous cystadenocarcinoma
Term
high grade squamous intraepithelial lesion (HSIL) of the cervix

1. includes CIN __ & __
2. s/s
3. labs/tests
4. abnormal colposcopy findings
5. indicaitons for diagnositic conization
6. tx
Definition

1. CIN II and III (moderate and severe dysplasia)

2. s/s: usually non. dx based on bx after abnormal pap

3. labs/tests: repeat cervical cytology q 6 mos until 2 consecutive normals, HPV test, schiller test, colposcopic exam,

4. colposcopy: leukoplakia, hyperkaratosis (white/thickened epithelium), acetowhite epithelium after acetic acid aplication, abnromal vasculature

5. diagnostic conization: unsatisfactory coploscopy, lesions extending into cervical cancal, dysplasia on endocervical curettage, adenocarcinoma, microinvasive carcinoma

6. tx:

- cryotherapy & laswer ablation - cannot produce tissue specimen for histology

- LEEP, cold knife conization, laser cone excision - can do histology

Term
fallopian tube:
1. normal length
2. 3 parts
3. blood supply
4. ligamentous support
Definition

 

1. 7-14 cm

2. isthmus (narrow and straight portion imediately adjoining uterus), ampulla (wider, more tortuous), infundibulum (funnel-like dilation)

3. ovarian and uterine arteries

4. suspensory ligament of ovary suspends infundibulum from pelvic brim

Term
Stages of fetal development:

1. ovulation of fertilized ovum - travels to uterus to form ____
2. day 6-7 after ovulation - implantation of ___
3. day 7-8: ___ proliferation
4. day 9-11: circulation of maternal blood
5. day 13-18: primary and secondary vili form, body stalk, and ____
6. day 18-21: teritary vili, ___ invades vili, fetoplacental circulation
7. Day 21-40: ___ forms. heart starts beating
8. day 40-50: ___ formation (subdivision of placenta)
9. 8 weeks: 1 g. milestones?
10. 12 weeks: 19 g. milestones?
11. 16 weeks: 100 g
12. 20 weeks: 300 g
13. 24 weeks: 600 g
14. 28 weeks: 1050 g
15. 32 weeks: 1700 g. % viable?
16. 36 weeks: 2500 g.
17. 40 weeks: 3200-3500 g.
Definition

1. blastocyst

2. blastocyst

3. trophoblast

4. maternal blood

5. amnion

6. mesoblast

7. chorionic plate

8. cotyledon

9. 8 weeks - head is half the bulk, hepatic lobes, RBCs, kidneys, ears/eye/nose/mouth/digits, tail almost gone

10. 12 weeks: skin pink, head still large, brain roughly complete, ossification of sarcal arches and bodies

11.16 weeks: sex discernible, hemoglobin F present, hemoglobin A begins, fetus active, heart well developed, lobulated kidneys, meconium in bowel

12. 20 weeks: moving a lot, uterus at umbilicus, sternum ossified

13. 24 weeks: fat deposits, 50% viable, vernix/os/pubis ossifies

14. 28 weeks: lungs functional, low surfactant, nails appear, testes at inguinal ring, talus ossifies

15. 32 weeks: 99% viable

16. 36 weeks: lanugo disappearing, testes in inguinal canal, scrotum small w/ few ruggae, distal femoral ossification centers

17. 40 weeks: silky hair, full testes, pendulous/rugous scrutum, proximal tibia ossificaiton

Term
Phases of ovarian cycle:

follicular phase:
1. day __: 1 follicle in 1 ovary strts to grow rapidly and becomes dominant follicle
2. day __: ovulation occurs - ovum picked up by fembriated ends of uterine tubes and transported to uterus. if fertilization does not occur, ovum degenerates and passes through uterus out vagina

luteal phase:
3. ___ forms, luteal cells secrete estrogen and progesterone. If pregnancy occurs, it persists. if not, it degenerates


Phases of uterine cycle:
4. ___ phase: day 1-14. restoration of epithelium from preceding menstruation. uterine glands lengthen
5. ___ phase: day 14-28. preparation of uteru for implantation of fertilized ovum. after ovulation, enodmetrium becomes highly vascularized and edematous under estrogen and progesterone . when fertilization fails, endometrium is shed and new cycle starts
Definition

1. day 6

2. day 14

3. corpus luteum

4. proliferative

5. secretory

Term
menstruation

1. contains?
2. usual duration
3. avg blood loss
Definition

 

1. contains arterial blood, tissue debris, prostaglandins, fibrinolysin. shouldn't have clots unless excessive flow

2. usual duration: 3-5 days

3. avg blood loss: 30 ml. ranges from spotting to 80 ml

 

Term
Ovulation:
1. definition
2. retrospective indicator of ovulation
3. rise in ___ occurs during rise LH surge - can be detected with at home kits
4. most fertile period?
Definition

1. around day 14, follicular rupture occurs, ovum extruded into abdomen and picked up by fembriated ends of fallopian tubes and transported to uterus

2. rise in basal body tempt

3. urinary LH

4. 48 hrs before ovulation

Term
Function of fetal testes
Definition

secrete mullerian inhibiting substances to prevent development of uterus, fallopian tubes, and vagina

 

secrete testosterone to form internal and external genitalia

Term
Ovarian agensis-dysgenesis disorders:

1. example?
2. s/s?
3. labs: gonadotropin, FSH/LH, estrogen
4. tx?
Definition

1. turner's (45x) or anything with streak gonads

2. s/s: newborns: edema of hands and feet

adolescents: short stature, sexual infantilism, webbed neck, growth retardation

3. labs: elevated gonadotropin, serum FSH >50, LH >90, low estrogen

4. tx: estrogen to assist in development of secondary sex characteristic, growth hormone for height, surgical removal of streak gonads

Term
True hermaphroditism

1. definition?
2. s/s
3. tx
Definition

 

1. presence of ovarian and testicular tissue

2. s/s: ambiguous genitalia, female-type breasts, menstruation, chimeric sex chromosomes (46XY/XX)

3. tx: surgical removal of contradictory organs, reconstruction of external genitalia

Term
what disease?

apparent males with small testes, azoospermia, gynecomastia, normal external genitalia, some metnal retardation

s/s usually present wtih puberty

elevated pituitary gonadotropin, low 17-ketosteroid excretion rate

genotype usually 47 XXY

tx?
Definition

klinefelter's

 

tx: usually none for infertility and gynecomastia

surgery, testosterone, donor sperm

Term
What disease?

>2 X chromosomes, mosaicism if 45X
gonadal agenesis common
s/s: normal body proportions, external genitalia of female, reduced ovarian follicles, small ovaries, irregular menstruation, MR
Definition
Multiple X syndrome
Term
Female hermaphroditism due to congenital adrenal hyperplasia

s/s
labs
tx
Definition

s/s: greatly enlarged clitoris may be mistaken for penis, no gonads w/in scrotolabial folds

- growth: grow more rapidly early in life but then stop growth about age 10

- virilization begins age 2 - pubic/axillary/body hair, beard, acne, no puberty

- electrolyte imbalance

- no ovulation

 

labs: high androgens and 17-hydroxyprogesterone

 

tx: high doses of hydrocortisone + surgical correction of external genitalia

Term
male hermaphroditism

cause?

s/s?

labs

tx
Definition

cause: defect in action of testosterone or fxn of testis

 

s/s: ambiguous genitalia

 

labs: deficiency in biosynthesis of testosterone

 

tx: endocrine, surgery, and psych consults

Term
Premature ovarian failure

1. definition

2. s/s
3. labs
4. tx
Definition

1. definition: cessation of menses <40 y/o

2. vasomotor flushes, atrophic vaginitis, decreased cervical mucus, osteoporosis

3. labs:

- increase in: LH and FSH

- decrease in : testosterone, estradiol, estrogen, progesterone

4. tx:

- atrophic vaginitis: lubricants, topical estrogens

- vasomotor flushes: estrogens, progestins, clonidine, SSRIs, gabapentin

- osteoporosis: 1200 mg Ca, 400-800 mg vit D, smoking cessation, avoid alcohol, weight-bearing exercise, bisphosphonates (alendronate, risedronate, ibandronate), calcitonin, estrogens, parathyroid hormone, SERMs (raloxifene), progestines

Term
what hormone?

secreted by hypothalamus, stimulates anterior pituitary to secrete FSH and LH
- normally secreted in episodic bursts to regulate menstrual cycle
- thecal cells in ovaries secrete estrogen, which inhibit the release of this hormone
Definition
GnRH
Term
Non-hormonal agents that bind to estrogen receptors
tx for osteoporosis

ex?
Definition
SERMs - raloxifene, tamoxifene, toremifene
Term
HRT
1. OCP benefits
2. indications
3. comlications
4. contraindications
Definition

OCPS: relieve hot flashes and regulate menstrual cycles during perimenopause

Indications: prevention of osteoporosis, tx of hot flashes and vaginal atrophy

Complications: all due to estrogen -endometrial cancer, breast cancer, DVT, stroke, vaginal bleeding, gallbladder dz, dyslipidemia,

Contraindications: undiagnosed abnormal vaginal bleeding, hx breast cancer, hx estrogen-dependent neoplasia, hx DVT/PE, hx MI or CVA, liver disease

Term
HRT for each problem:

osteoporosis
hot flashes
atrophic vaginitis
Definition

osteoporosis: low dose (0.014 mg/d) transderman estrogen

 

hot flashes: standard dose conjugated estrogen (0.3-0.625 mg/d), 0.025 mg/d transdermal estrogen, or 0.5 mg/d oral estrogen

 

atrophic vaginitis: 0.25-0.2 g topical estrogen for 2 weeks, then 25 ug estradiol PO for 2 weeks, then weekly, then estradiol ring for 3 months

 

combined, continuous estrogen + progestin is most common

 

long term OCP no longer recommended due to cardiovascular risk

Term
Presumptive manifestations of pregnancy
Definition

symptoms: amenorrhea, n/v, breast tenderness (mastodynia), breast discharge (colostrum), enlargement of sebaceous glands in areola, quickening, bladder irritability/frequency/nocturia, UTI

 

signs: increased basal body temp, chloasma (darkening of skin over forehead/cheeks), linea nigra (darkening of nipples and linea alba), stretch marks, spider telangiectaisas

Term
When is quickening first felt?
Definition

primi: 18-20 weeks

multi: 14-16 weeks

Term
hormonal causes of each sx:
amenorrhea
n/v
Definition

amenorrhea: estrogen/progesterone by corpus luteum

 

n/v: rapidly rising hCG

Term
Probable/presumptive manifestations of pregnancy

sx are same as presumptive

signs:
1. bluish/purple discoloration of vagina and cervix
2. vaginal d/c consisting of epithelial cells and cervical mucus
3. widening of softened areas of isthmus
4.
5.
6.
7. softening of anterior wall of uterus
8. softening of cervix
Definition

1. chadwick's sign

2. leukorrhea

3. hegar's sign

4. relaxation of pelvic joints

5. abdominal enlargement

6. uterine contractions

7. Ladin's sign

8. Goodell's sign

Term
when do braxton hick's begin?
Definition
28 weeks
Term
positive manifestations of pregnancy

1. fetal heart tones as early as __ weeks. rate __-__ bpm
2. palpation of fetus at __ weeks
3. cardiac activity on US __ weeks
4. limb buds __-__ weeks
5. finger/limb movement __-__ weeks
6. urine pregnancy test: hCG peaks at __-__ weeks, can be detected as early as __ after gestation
Definition

1. FHT: 10 weeks. 120-160

2. Palpation of fetus: 22 weeks

3. cardiac: 5-6 weeks

4. limb buds 7-8 weeks

5. finger movements: 9-10 weeks

6. 10-12 weeks, 1 week

Term
gonadotropin secreted from anterior pituitary responsibel for early maturation of ovarian follicle

elevated during follicular phase, peaks at midcycle, decreases during luteal phase
Definition
FSH
Term
Perinatal period = ?
number of lives lost during this period are appx equal to number lost during first __ years of life
1/2 occur ___
70% of deaths in first year of life happen in first __ days
Definition

perinatal period: 28 weeks - first 7 days of life

deaths = first 40 years of life

1/2 occur in utero

70% occur in first 28 days

Term
Preterm labor
1. __% idiopathic
2. s/s
3. labs/tests
4. 2 general causes
Definition

1. 50%

2. s/s: uterine contractions > 2/hr, dilation/effacement, vaginal bleeding, bloody show

3. tests: US - gestational age, fetal weight, presenting part, fetal monitoring

CBC w/ diff

UA

amniocentesis - fetal lung maturity

cervical culture: GC/chlamydia

fetal fibronectin - neg test r/o delivery w/in 2 weeks

4. cervical incompetence, preterm uterine contractions

5. tx: bed rest, hydration, corticosterones, tocolysis

 

Term
tocolysis - drugs and purpose
Definition

purpose: delay labor to allow corticosteroids to mature fetal lungs

 

drugs:

- beta mimetics (terbutaline)

- magnesium sulfate

- calcium channel blockers

- prostaglandin synthase inhibtiors (indomethacin)

 

try multiple drugs if one fails

Term
Premature Rupture of Membranes
1. definition: __ hr elapse of time between rupture and onset of labor.
2. important sequelae?
3. s/s
4. labs/tests
Definition

1. 24 hr

2. chorioamnionitis

3. s/s: hx of gush of fluid from vagina or watery vaginal d/c, sterile speculum exam looking for pooling amniotic  fluid in posterior fornix, nitrazine test demonstrating an alkaline pH, presence of ferning when placing fluid on slide and allowed to air dry

4. labs/tests:

CBC w/ diff

UA

US - fetal size, amniotic fluid index

amniocentesis - fetal lung maturity, infection

Term
what dx?

fever, maternal leukocytosis, uterine tenderness, tachycardia, foul-smelling amniotic fluid

tx?
Definition

chorioamnionitis

tx: delivery, regardless of gestational age
broad spectrum abx
oxytocin to induce labor
24-32 weeks: abx, corticosteroids, tocolytics for 48 hrs, then deliver

Term
Prolonged pregnancy:

1. definition
2. .most common cause
3. maternal risks
4. labs/tests
5. tx
Definition

1. definition: 42 weeks from first day of LMP or 40 weeks from time of conception

 

2. most common cuase: incorrect dating

3. maternal risks: fetal size, birth injury, placental insufficiency, olioghydramnios, cord compromise

 

4. labs/tests:

NST 2x/week

US 2x/week for biophysical profile and amniotic fluid

Mother does fetal movement counts daily

5. tx: expectant managemnet - induction does not decrease c/s rate

Term
how does Rh isoimmunization occur?

s/s
Definition

Rh-neg mom gives birth to Rh-pos baby. fetal RBC pass to mom. mom makes abs against Rh antigen.

future pregnancies may develop hemolysis due to maternal antibodies

 

s/s:

fetal: anemia, immature rbc, high bilirubin, erythroblastosis fetalis

neonate: anemia, hyperbilirubinemia

 

tx:

screen for ABO and Rh group

28 week visit: ab screening performed, if neg - give 300 ug RhIgG or Rhogam

35 week: repeat ab screening. if pos - manage pt as rh-sensitized

postpartum: if baby is Rh-pos or Du-pos, give Rhogam

Term
S/S: pallor, clammy skin, syncope, thirst, dyspnea, restlessness, agitation, anxiety, confusion, falling BP, tachycardia, thread pulse, oliguria --> in third trimester
Definition

hemorrhage

 

tx:

ABC's

trendelenburg

fetal monitoring

blood transfusion, Ca, K

 

Term
premature separation of placenta:

1. concealed vs. external
2. risk factors
3. US?
4. tx
Definition

1. concealed: hemorrhae confied within uterine cavity

external: blood drains through cervix

 

2. risk factors: previous separation, HTN, advanced maternal age, multiparity, vascular disease, smoking, alcohol, cocaine

3. US often inconclusive

4. tx: IV, PRBC, vaginal delivery, c/s if fetal distress

Term
placenta previa:
1. risk factors
2. complete vs. marginal
3. s/s
4. tests
5. tx?
Definition

1. risks: multiparity, advanced age, previous c/s, mechanical separation, placentitis, rupture of venous lakes

2. complete: completely covers internal os

marginal: w/in 2 cm of internal os

3. s/s: painless hemorrhage, usually around 28 weeks

4. US

 

5. tx: expectant - transfusions, tocolysis, test fetal maturity

delivery - c/s is method of choice

6. complications: hemorrhage, shokc, death, bleeding, operative trauma, infection, embolism, prematurity

Term
first stage of labor:
1. defition?
2. duration?
3. diet
4. monitor
Definition

1. definition: onset of labor to full cervical dilation

2. duration: primi - 6-18 hr, multi - 2-10 hr

3. sips and ice chips

4. maternal pulse and bp q 2-4 hr

fetal hr q 30 min

uterine contractions q 30 min

cervical dilation

Term
second stage of labor:
1. definition
2. duration
3. monitor


steps of fetal progression
Definition

1. fullcervical dilation to delivery of baby

2. duration: primi - 30 min-3 hr

multi: 5-30 min

3. monitor fetal hr q 15 min

 

fetal progression:

§  Engagement of presenting part: head enters pelvis

 

§  Flexion: aids in engagement and descent

 

§  Descent: continues progressively

 

§  Internal Rotation: rotate to pass the ischial spines

 

§  Extension: must occur to allow head to bass through vaginal outlet

 

§  External Rotation: rotates to position it occupied at engagement

 

·       Delivery anterior shoulder: gentle traction downward

 

·       Delivery posterior shoulder: gentle traction upward

 

 

Term
third stage of labor
1. definition
2. duration
3. signs of placental separation
Definition

1. definition: delivery of baby - delivery of placenta

2. duration: 0-30 min

3. placental separation: fresh show of blood from vagina, umbilical cord lengthens

fundus raises up

uterus firm and globular

Term
___: from delivery of baby and placenta to 6 weeks post-partum
Definition
puerperium
Term
what is bishop scoring?
Definition
combo of cervical dilation, effacement, station, consistency of cervix, position of cervix
Term
DEXA scan
1. best test to measure ___
2. normal, osteopenic, and osteoporotic scores
3. Recommended testing times
Definition

1. bone density

2. normal: T score >-1.0 SD

osteopenic: T score -1.0-(-2.5)

Osteoporotic: T score <-2.5

3. recommendations: postmenopausal <65 y/o

all women >65 y/o

women considering osteoporosis therapy

women on HRT for prolonged therapy

 

Term
Immunizations during pregnancy:
1. which kids are safe
2. __ is indicated for all women pregnant during october to march
3. 4 vaccines that are ok during pregnancy
4. 3 vaccines that may be given 3 mons prior to pregnancy or postpartum
Definition

1. killed viruses, toxoid, recombinant

2. flu

3. diphtheria, tetanus, hep b, killed polio

4. MMR, polio, varicella

Term
Complications assocaited with premature ovarian failure
Definition

definition: spontaeous cessation of menses before 40 y/o

 

complications & tx:

atrophic vaginitis - topical estrogens

hot flashes - estrogens & progestins

osteoporosis - calcium, vit D, smoking cessation

vaginal dryness/dysparuenia

atrophic cystitis

urethral caruncle w/ dysuria

breast regression

Term
Factors that influence labor

1. ___ - when the fetal head settles into the pelvic brim, occurs 2 weeks before labor for 1st pregnancy, at onset for multiparous
2. ___ before labor - cervix begins to soften, efface, and dilate
3. passage of mucus plug = "____"
Definition

1. lightening

2. weeks

3. bloody show

Term
Complications of labor
1. occur in __% of nulliparous pts
2. prolonged latent phase - >__ hr. tx?
3. cervical protraction: <__ cm/hr in nulliparous or <__ cm/hr in multiparous
4. protracted descent of fetus: <__ cm/hr in nulliparous or <__ cm/hr in multiparous
5. arrest of dilation: no progressive dilation w/in __ hr
6. arrest of descent: no progress w/in __ hr
7. precipitate labor: delivery <__ hr from onset of contractions
8. precipitate dilation: >__ cm/hr in primi or >__ cm/hr in multi - problems with this? - tx?
Definition

1. 25%

2. >20 hr. tx with bedrest, sedation, or oxytocin

3. cervical protraction: <1.2 cm/hr in nulliparous, <1.5 cm/hr in multiparous

4.protracted descent: <1 cm/h in nulliparous or <2 cm/h in multiparous

5. arrest of dilation: 2 hr

6. arrest of descent: 1 hr

7. precipitate labor: <3 hr

8. precipitate dilation: >5 cm/h primi or >10 cm/hr multi - can cause placental abruption, uterine rupture, PP hemorrhage - tx: stop oxytocin, give terbutaline/ritrodine

Term
Pelvic shapes:
1. best for vaginal delivery
2. male type - can cause OP and transverse arrest
3. black > white. can cause transverse arrest
4. most rare. can cause transverse arrest
Definition

1. gynecoid

2. android

3. anthopoid

4. platypelloid

Term
Fetal Malpositions:
1. 2 types of vertex malpositions
2. occurs in 0.06%. associated with pelvic contraction, prematurity, and grand multiparity. spotaneously corrects in 1/3. need c-section otherwise. do not use oxytocin
3. occurs in 0.2%. associated wtih grand multiparity, advanced maternal age, pelvic mass, pelvic contraction, multiple gestation, polyhydramnios, macrosomia, congenital anomalies, prematurity, cornual implant, placenta previa, and PROM
4. fetus lies at transverse/oblique angle to maternal long axis. can do external cephalic version (ECV) before labor
Definition

1. occiput posterior and occiput transverse

2. brow presentaiton

3. face presentation

4. abnormal fetal lie

Term
birth weight >90th percentile or >4000-4500 g.

risk factors?
Definition

macrosomia

 

risk factors: maternal DM, obesity, excessive maternal weight gain, postdate pregnancy

 

risk for shoulder dystocia

Term
most common fetal malformation
Definition
hydrocephalus
Term
5 obstetrical emergencies
Definition

shoulder dystocia

fetal compromise

placenta previa

fetal blood loss

vasa previa

Term
inability to deliver shoulders after the head

associated with macrosomia, dm, prolonged 2nd stage of labor, instrumental delivery -- if any of these are present, pt should be offered a c/s

what to do:
1. call for help
2. episiotomy
3. mcroberts maneuver
4. rubin maneuver
5. wood's maneuver
6. barnum maneuver
Definition
shoulder dystocia
Term
fetal compromise
1. definition

2. what to do?
Definition

1. decreased fhr or decrease in variability

 

2.

a. vaginal exam

b. mom to lateral position for intrauterine resuscitation

c. correct maternal hypotension

d. stop oxytocin

e. deliver

Term
hallmark: painless vag bleeding during 2nd or 3rd trimester

tx?
Definition

placenta previa

 

DO NOT DO CERVICAL EXAM

 

needs c/s

 

Term
vaginal bleeding + FHR abnormalities
Definition
placental abruption --> deliver immediately
Term
normal fetoplacental vascular volume

signs that fetus has lost blood

test to determine fetal hgb?
Definition

250-500 ml

 

fetal tachy, recurrent decels, prolonged brady, sinusoid pattern

 

kleihauer-betke test

Term
when umbilical vessels cross internal os in advance of fetal persenting part - likely to be disrupted during labor, causing fetal bleeding

dx: fetal tachy after rupture of membranes


tx?
Definition

vasa previa

 

tx: emergency c/s

Term
DM in pregnancy increases risk of....
Definition

spontaneous abortion

congenital anomalies

macrosomia

shoulder dystocia

operative delivery

birth trauma

neonatal hypoglycemia

resp distress syndrome

hypocalcemia

hyperbilirubinemia

 

fetal malformations due to hyperglycemia occur in first 8 weeks of pregnancy, so all DM pts should recieve periconceptional care

Term
maternal glucose levels in 1st trimestr vs. 2nd and 3rd
Definition

1st trimester: estrogen and progesterone cause decreased fasting glucose

2nd/3rd: decreased insulin sensitivity

 

 

Term
managing breech presentaiton
Definition

>36 weeks - external cephalic version

c/s if not corrected

Term
role of glucocorticoids during pregnancy
Definition
given over 48 hrs to accelerate fetal lung maturation
Term
PID Dx
Definition

uterine, adnexal, or cervical motion tenderness and absence of competing dx

 

PLUS one of these:

 

>38.3C or 101F

increased ESR

increased WBC

inflammatory mass

gram neg intracellular diplococci

Term
PID
1. most common agents
2. always r/o what two things?
3. workup?
4. risk factors
5. tx
Definition

1. gonorrhea or chlamydia

2. r/o ectopic and appy

3. pelvic US, UPT, CBC, ESR, genital cultures, UA

4. risk factors: multiple partners, young, nulliparous, non-white, douching, smoking, IUD

5. cefoxitin IM + probenecid PO + ceftriaxone IM

Term
Gardnerella vaginalis:
1. results from loss of natural ___ bacteria
2. clinical criteria?
3. tx
Definition

1. lactobacilli

2. homogeneous white d/c, microscopic presence of >20% clue cells, vaginal d/c with pH > 4.5, fish odor

3. Flagyl PO, clinda cream, or flagyl cream

Term
Ovarian Cysts
1. characteristics of benign cysts
2. characteristics of malignant cysts
3. workup
Definition

1. benign: smooth, mobile, <10 cm, calcium, painless

2. malignant: fixed, solid, septation >3mm, ascites, abd pain, bloating, nausea, early satiety, munstraul abnormalities

3. workup: US, CBC, CMP, hCG, CA-125, AFP, LDH

Term
cyst that is part of the normal menstrual cycle. should not be painful. rupture wtih ovulation.

cysts >6cm should be followed with US to make sure they disappear
Definition
benign functional cyst
Term
Side effects of oral contraceptives
Definition
increased risk of MI, DVT, CVD, cervical dysplasia, HTN, HA, decreased quality/quantity of breast milk, depression, nausea/dizziness, weight gain 2-5 lbs, fatigue, decreased libido
Term
contraindications to steroid contraceptives
Definition
absolute: pregnancy, dvt, CAD, breast ca, undiagnosed abn vag bleeding, estrogen-dependent ca, liver tumor, uncontrolled htn, DM, >35 y/o and smoking >15 cig/day, thombophillia, migraine w/ aura, acitive hepatitis, surgery requiring prolonged imobilization
Term
1. ~__% of pts with BRCA1 will develop breast cancer
2. ~__% of pts wtih BRCA2 will develop breast cancer
3. when is BRCA screening indicated?
Definition

1. 85%

2. 40%

3. screening: dx with breast ca <40 y/o, 1st deg relative with breast ca <50, women w/ family hx of male or multiple breast cancers, sngnificant neoplasms (ovarian, colon, pancreatic)

Term
Characterized by chronic anovulation, polycystic ovaries, hyperandrogenism
associated wtih hirsutism, obesity, insulin resistance
increased risk of DM, CVD, metabolic syndrome

workup?
tx?
Definition

PCOS

 

workup: FSH, LH, prolactin, TSH - to r/o other causes

testosterone, 17-hydroxyprogesterone

 

 

tx:

exercise, weight loss, metformin

clomiphene: infertility

OCPs: hirsutism

Term
basis of female infertility with aging
Definition

less frequent ovulation + lower quality eggs

 

Term
hormones involved in breast feeding
Definition

estrogen, progesterone, prolactin, GH, insulin, cortisol, epithelial growth factor

 

prolactin is stimulated by suckling, nipple stimulation, crying infant, positive attitude

Term
germ cell tumor that is rubbery, smooth, round, and encapsulated wtih brown/gray color

AFP is borderline high
hCG may be pos or neg
Definition
ovarian dysgerminoma
Term
germ cell tumor composed of any of the 3 germ cell layers
may have hair and teeth
account for 40-50% of benign ovarian neoplasms in reproductive age women and are usually asymptomatic unless complications such as torsion/rupture occur

usually found in women <20
AFP +/-
hCG negative

AKA dermoid cysts

dx via US
removed laparoscopically

which are malignant?
Definition

ovarian teratoma

 

immature teratomas are malignant, mature are benign

 

 

Term
potential causes of elevated hCG w/ empty uterus
Definition

ectopic

ovarian tumors: dysgerminoma, mixed germ cell tumor, choriocarcinoma, embryonal carcinoma

Term
Mastitis:
1. cause
2. sx
3. tx
4. what does recurrent mastitis suggest?
Definition

1. staph

2. fissured, red, warm, sore nipple

3. tx: dicloxacillin or cephalosporin, keep nursing, stop if abscess

4. recurrent = neonatal strep infx

Term
PMS:
1. definition
2. management
3. ___: if sx disrupt daily fxn
Definition

1. 7-14 d before menstruation - should quit w/ menstruation

2. pt chart sx, diet and avoid triggers, Ca/Mg/B6/Vit E/NSAIDS, SSRI, OCP

3. PMDD

Term
Breast cancer:
1. __ leading cause of cancer death in women
2. 1/_ lifetime risk
3. risk factors?
4. early findings
5. late findings
6. breast exam recs
7. mammogram recs
8. what to do if you find a lump?
9. most malignant form?
10. tx?
Definition

1. 2nd

2. 1/8

3. risk: delayed childbearing (>35), fm hx, BRCA 1 or 2, personal hx of breast cancer, mecarch <12, menopause >50

4. early: single, nontender, firm mass with ill defined margins; mammogram abn w/ no palpable mass

5. late: skin/nipple retraction, axillary adenopathy, breast enlargment, erythema, edema, pain, fixation of mass to skin or chest wall

6. breast exam: 20-40 y/o every 2-3 years, >40 yearly

7. mammogram: >40 1-2 years, >50 yearly

8. lump - diagnostic mammogram

9. most malignant: inflammatory

10. tx: surgery + adjunctive therapy. just palliative if stage IV, mammogram q 6 mos for 2 yr

Term
LOOK UP BREAST CANCER BY QUADRANT
Definition
Term
most common cause of post-menopausal bleeding
Definition
exogenous hormones
Term
1. inability of a couple to conceive w/in 1 year
2. those who have never conceived
3. probability of achieving live birth w/in 1 menstrual cycle
4. likelihood of conception per month of exposure

__% of couples having unprotected sex will conceive w/in 1 yr
Definition

1. infertility/subfertility: inability of a couple to conceive w/in 1 year
2. sterility: those who have never conceived
3. fecundity: probability of achieving live birth w/in 1 menstrual cycle
4. fecundibility: likelihood of conception per month of exposure

 

90%

Term
4 key things to test for infertility
Definition

male sperm analysis

oocytes

egg stransport

implantation of ova

 

Term
Male infertility:
1. majority are due to ?
2. normal semen analysis: count, motility, volume, morphology
Definition

1. testicular pathology - varicocele

2. count: >20M/ml

motility: >50%

volume: >2 ml

Morphology: >30% normal

Term
Female infertility:
1. workup
2. check FSH and estradiol on cycle day __, check progesterone on day __
3. sx of cervical cause of infertility
4. tx plan
Definition

1. pelvic US, urinary LH, basal body temp, endometrial bx, cervical mucus, hysterosalpingogram, sonohysterogram, laparoscopy w/ chromointubation (gold standard for assessing tubes)

2. FSH/estradiol: day 3, progesterone day 21

3. hx abnormal pap, post-coital bleeding, cryotherapy, conization, DES exposure

4. clomid (starting day 3-5 of cycle for 5 days) --> hCG + IUI --> IVF

Term
Drug Classes in Pregnancy:

1. animal studies have shown adverse effect on fetus but no adequate studies in humans; benefits may outweigh risks
2. aequate studies in pregnant women fail to show risk to fetus
3. animal/human studies shown fetal abnormalities or toxicity, risks outweigh benefits
4. pos evidence of human fetal risk, benefits may outweigh risks
5. animal studies failed to show risk but no adequate human studies - or animal studies show risk but human studies don't
Definition

1. C

2. A

3. X

4. D

5. B

Term
measuring uterine size during pregnancy:
1. size of your fist
2. smaller than fist
3. palpable at pubic symphysis
4. palpable at umbilicus
5. palpable at xiphoid
Definition

1. not pregnant

2. nulliparous

3. 12 weeks

4. 20 weeks

36 weeks

Term
mucopurulent d/c + bleeding
Definition
cervicitis
Term
abortions:
1. most common complication of pregnancy
2. in 20-30% of pts in first trimester
3.abdominal/back pain + bleeding with open cervix
4. severe/persistent bleeding + cramps
Definition

1. spontaneous abortion

2. implantation bleed

3. inevitable abortion

4. incomplete abortion

 

Term
potential causes of 3rd trimester bleeding (7)
Definition

bloody show

placenta previa

vasa previa

placental abruption

DIC

uterine rupture

non-OB (cervical pathology, vaginal pathology)

Term
most common cause of non-OB maternal death in pregnancy?
most common cause of fetal death?
Definition

MVA

death of mother, placental abruption

Term
Pre-eclampsia:
1. classic diagnostic triad, PE
2. bimodal peak
3. kidney damage
4. tx for mild
5. tx for severe
Definition

1. htn, edema, proteinuria, PE: brisk patellar reflexes, clonus

2. young nulliparous and >35 multiparous

3. kidneys: glomeruloendotheliosis

4. mild: <37 weeks: corticosteroids + bed rest

>37 weeks - induction

5. severe: <24-34 weeks: corticosteroids + mag sulfate

>34 weeks: delivery

Term
eclampsia
- risks
- tx
Definition

risks: tonic clonic seizure

tx: ABCs, diazepam/lorazepam, deliver baby!

Term
HELLP syndrome:
1. definition
2. sx
3. tx
Definition

1. variant of pre-eclampsia characterized by: Hemolysis, Elevated Liver enzymes, and Low Platelets

2. sx: RUQ pain, malaise, n/v

3. tx: delivery then dexamethasone

Term
nutrition during pregnancy:
1. Protein
2. calcium
iron
folic acid
Definition

protein: 1 g/kg/d + 20 g/d --> appx 80 g/day

calcium: 1.5 g/day

iron: 30 mg/day

folic acid: 4 mg/d if prior NTD, 0.4 mg/d if not

Term
Condyloma acuminate:
1. cause
2. incubation
3. lesions
4. sx
5. bx
6. tx
Definition

cause: HPV

incubation: >3 mos

lesions: papillary growths that coalsece into cauliflower masses, tend to proliferate during pregnancy

sx: pruritis, vaginal d/c, post-coital bleeding

bx: koliocytes

tx: trichloracetic or bichloracetic acid (TCA or BCA), podophyllin gel, cryosurgery/electrocoagulation

Term
Androgen insensitivity syndrome:

1. definition
2. presents as ____
3. What organs does the pt have and not have?
4. tx?
Definition

1. testicular feminization with 46.XY genotype due to deficeincy in androgen-binding protein --> creates male hermaphroditisim

2. presents as amenorrhea

3. has vulva and breasts secondary to unopposed estrogen but no uterus or vagina or body hair bc body is not responseive to testosterone. testes made by mullerian inhibiting factor = mullerian agenesiis

4. tx: address gender identification and remove undescended testes

Term
When germ cells fail to migrate from yolk sac to genital ridge in embryonic development, ___ occurs and the pt will have a female phenotype and male genotype. the result is a non-fxnal "____ ____"

what genitalia will they have?
Definition
female genitalia including vagina and uterus + streak gonads
Term
What does aromatase do?
what are aromatse inhibitors?
Definition

converts testosterone to estrogen

 

aromatase inhibitors (anastrozole, etrozole) and inactivators (exemestane) block conversion of androgens to estrogens --> good for breast cancer

Term
Cervical cancer risk factors
Definition

multiple partners, early onset of sexual activity, high risk sexual partners, HPV infection, hx STDs, smoking, HIV, AIDS, multiparity, long term OCP use

 

condoms do not entirely protect against HPV - can be transmitted from scrotal-labial contact

 

Term
Gestational DM

1. definition
2. complications
3. tx


glucose goals:
1. fasting
2. 1 hr post-prandial
3. 2 hr post-prandial
Definition

1.  any degree of glucose intolerance w/ onset during pregnancy

2. complications: macrosomia, polyhydramnia, miscarriage, fetal malformation, hypoglycemia in baby, preterm birth, pyelo, preeclampsia, in utero meconium, fetal hr abn, c/s, still birth

3. tx: BG control, non-weight bearing/low-impact exercise, diet 1800-2400 cal/day, insulin, birth 38-39 weeks

 

1. 70-95 fasting

2, <140 1 hr pp

3. <120 2 hr pp

Term
most common cause of asymptomatic bacteruria?
Definition
e. coli
Term
urinary frequency, dysuria, urgency, suprapubic discomfort, cloudy/malodorous urine
Definition
acute cystitis
Term
fever, shaking chills, flank pain, n/v, ha frequency, dysuria, bacteria endotoxiemia, endotoxic shock, renal insuff, anemia, leukocytosis, thrombocytopenia, elevated fibrin split products, preterm labor, fetal death, pulmonary dysfunction, ARDS
Definition
pyelo
Term
anovulation:
1. which hormone isn't working?
2. usually a dysfunction of ___
3. organic causes?
4. sx?
Definition

1. progesterone

2. hypothalamic pituitary axis

3. thyroid/adrenal dysfunction

4. irregular bleeding, absence of ovulatory temp changes, low serum progesterone

Term
what happens to AFP levels in NTD and Down's?
Definition

NTD: high maternal serum levels

Down's: decreased levels + increased hCG

Term
Amenorrhea
1. three things that must be intact for normal menstruation
2. primary amenorrhea
3. secondary amenorrhea
4. most common cause of secondary amenorrhea
5. workup?
Definition

1. hypothalamic-pitutiary axis, endometrium responsive to horomes, outflow tract from internal to external genitalia

2. absence of menses by age 15

3. absence of menses for 3 cycles or 6 mos

4. pregnancy

5. PREGNANCY TEST, TSH, prolactin, pelvic exam (establish presence of organs), US, serum testosterone

Term
causes of menorrhagia (hypermenorrhea)
Definition

tumor

myoma

pregnancy complication

IUD

hyperplasia

dysfunctional bleeding

 

Term
Galactorrhea:
1. most common causes in non-lactating women?

DDX:
a. unilateral serous or serous-sanguineous d/c
b. premenopausal, spontaneous, multiple ducts, green/brown, unilateral/bl, increased before menses
c. milky
d. purulent
Definition

1. carcinoma, intraductal papilloma, fibrocystic changes

 

a. intraductal papilloma or malignancy

b. fibrocystic changes

c. prolactinemia or OCP

d. subareolar abscess

Term
most common reportable disease
sx: may be asymptomatic, may have mucopurulent d/c, hypertrophic cervical inflammation, salpingitis

dx: cell culture, geimsa stain

tx?
Definition

chlamydia

 

tx: doxy or azithromycin

pregnancy: erythromycin or amoxicillin

Term
gram neg diplococci
20-40% co-infection w/ chlamydia

discharge, urinary frequency, dysuria, rectal pain, vaginal itching/burning
bartholinitis
pharyngitis
conjunctivitis

dissemination: polyarthralgia, tenosynovitis, dermatitis

labs: thayer-martin stain
Definition

gonorrhea

 

reportable

 

tx: ceftriazone/cefixime + doxy or azithromycin

Term
Candida:

1. conditions associated
2. sx
3. dx
4. tx
Definition

DM, HIV, obesity, pregnancy, abx, steroids, OCP, debilitation

 

pruritus, white/cheesy d/c, vulvuar erythema, burning w/ urination

 

KOH prep

culture is gold standard

 

tx: nystatin PO or cream, clotrimazole/ketoconazole/fluconazole

Term
unicellular flagellate protozoan that infections lower urinary tract in men and women
sx: persistent frothy green vaginal discharge +/- pruritus, strawberry spots on vag epithelium

tx?
Definition

trichomonas

 

tx: metronidazole x 1

Term
painless sore/chancre on labia/vag/cervix/anus + painless lymphadenopathy

tx?
Definition

primary syphilis

 

tx: benzathine pcn G IM x 1, tetracycline or doxy for 14d for PCN allergy

Term
systemic infx w/ diffuse adenopathy, papulosquamous rash on palms, soles, trunk; alopecia, hepatitis, nephritis, condyloma lata

tx?
Definition

secondary syphilis

 

tx: benzathine PCN G

Term
syphilis of <1 yr duration with primary and secondary lues
still contagious
tx?
Definition

latent syphilis

 

tx: benzathine PCN G

Term
indeterminate or >1 yr syphilis
Definition

late latent syphilis

 

get CSF study to r/o neurosyphilis

 

 

Term
Congenital syphilis
sx?

will baby's test be reactive
Definition


always systemic disease - organomegaly, osteochondritis, anemia, jaundice, skin lesions, rhinitis, adenopathy, CNS disease

 

baby's test is reactive

 

tx: put baby in isolation, treat if rising titer

treat mom before 18 weeks to prevent transmission

Term
caused by chlamydia species

vesiculopustular eruption
vaginal ulceration, lymphedema
excrutiating pain
red-purple induration
rectal stricture makes defecation difficult
vaginal distortion = dyspareunia
late phase: fever, chills, HA, arthralgia
Definition

lymphogranuloma venereum

 

tx: REPORT

- doxy or erythrombycin for 21 days

Term
cause: calymmatobacterium granulomatis

malodorous d/c, inguinal swelling, abscess (bubo)

large macrophages w/ rod-shaped inclusions (MIKULICZ CELLS and DONOVAN BODIES)

tx?
Definition

granuloma inguinale (donovanosis)

 

tx: bactrim or doxy x 3 weeks --> NOT PCN

Term
organism: H. ducreyi (gram neg rod)

sx: inguinal adenitis w/ erythema and fluctuance, vesiculopustular lesions becoming saucer-shaped ragged ulcer w/ inflammatory wheal. very tender, foul d/c, adenitis, buboes

tx?
Definition

chancroid

 

tx: report

r/o syphilis

sitz baths, azithromycin + ceftriaxone + erythromycin + cipro

Term
Herpes Simplex

1. incubation
2. how long do lesions last?
3. testing?
Definition

incubation: 2-7 d

lasts 2-6 weeks

tzanck smear

 

Term
congenital herpes:

1. __% transmission rate
2. infx in newborn has __% mortality rate
3. __% of survivers have neurologic/ocular sequelae
4. initiate antiviral therapy at __ weeks gestation
Definition

1. 40-50%

2. 60%

2. 50%

4. 36 weeks

Term
cause: HPV
incubation: >3 mos
sx: papillary growths coalescing into cauliflower masses
pruritus, vaginal d/c, post-coital bleeding

bx: koliocytes

tx?
Definition

condyloma acuminate

 

tx: trichloaracetic or bichloracetic acid (TCA or BCA), podophyllin gel, cryosurgery/electrocautery

Term
physiologic changes during pregnancy

1. thick vaginal d/c
2. heart
3. resp
4. heme
5. renal
6. gi
7. msk, pubic symphysis separates at __ weeks
8. colostrum at __ weeks
Definition

1. leukorrhea of pregnancy

2. CO increase by 30-50%, SEM

3. 20% increased need for O2

4. 35% increase in blood volume

5. decreased bladder tone and capacity, NOT proteinuria

6. n/v/pica/gerd/constipation

7. progesterone = laxity of ligaments, pubic symphysis at 28-30 weeks

8. 16 weeks

 

Term
C-Section indication
Definition

repeat

cephalopelvic disproportion/dystocia

 malposition/malpresentation

fetal distress

placenta previa/multiple gestation/fetal abnormalities, cervical cancer, active herpes

Term
Indications for hysterectomy
Definition

treatment of cancer

benign GYN conditions (endometriosis, dysmenorrhea, menorrhagia)

obstetric complications

Term
Endometriosis **
1. early vs. advanced lesions
2. most common place for lesions
3. three most common presenting sx
4. tx
Definition

1. early: red petechial lesions. later: dark brown/blue endometriomas or "chocolate cysts"

2. ovary

3. infertility, dysmenorrhea, dyspareunia

4. expectant management, nsaids, OCP, progestins, danazol, GnRH agnoists (leuprolide), hysterectomy

Term
what tumor?**

malignant tumor of ovary
histologically: budding tufts, PSAMMOMA BODIES

sx: insidious onset, long-standing hx of non-specific abd pain, GI complants, dyspepsia, altered bowel habits

tx?
Definition

serous cystadenocarcinoma

 

tx: surgery

Term
Cervical dysplasia of CIN 2 or 3.
tx with LEEP
do colposcopy first
Definition
high-grade squamous intraepithelial lesion (HSIL)
Term
what hormone spikes before egg is released? **
Definition
LH
Term
spontaneous cesseation of menses <40 y/o
climacteric sx: hot flushes, secondary amenorrhea
HIGH FSH
Definition
premature ovarian failure/premature menopause
Term
clinical presentaiton of ____:
- ambiguous genitalia
micropenis
clitoromegaly
partial labial fusion
undescended testes
labial/inguinal masses in girls
hypospadias
delayed/absent puberty
electrolyte abn
Definition
intersex disorders
Term
what hormone? **

released in pulsatile fashion from hypothalamus - modulates secretion of gonadotropin
is measured by measuring LH

agonists of this hormone (Leuprolide) are used for tx of endometriosis
Definition
GnRH
Term
normal pregnant woman who is not anemic requires supplementation of ___ mg/d iron
Definition
60
Term
severe NVP in pregnancy, which can result in weight loss, ketonuria, and electrolyte imbalance

due to hCG increase
Definition
hyperemesis gravidarum
Term
hormone responsible for maturation of ovarian follicles ***
Definition
FSH
Term
hormone that triggers ovulation and the initial formation fo the corpus luteum as well as secretion of estrogen and progesterone
Definition
LH
Term
Stages of labor **

1. begins with contractions - to achieve dilation and effeacement - ends with full dilation

2. irregular to regular contractions with little/no progress

3. regular progress expected, failure to progres is potential problem

4. from full dilation to delivery of baby

5. placental delivery
Definition

1. first stage

2. latent phase

3. active phase

4. second stage

5. third stage

Term
third trimester bleeding ***
1. painless bleeding
2. painful bleeding
Definition

1. placenta previa -- do not do cervical exam

2. abruptio placentae

Term
what imaging is used for the most accurate dx of osteoporosis? **
Definition
DEXA scan
Term
Vaginal Discharge: **
1. Muco-purulent (mucous + pus) cervicitis with hypertrophic cervical inflammation= Chlamydia
2. Purulent (pus) vaginal d/c and dysuria = gonorrhea (but most are asymptomatic)
3. Frothy greenish discharge sometimes foul smelling; “strawberry cervix” = trichomonas
4. “Cottage cheese” looking d/c with severe itching = yeast
5. White/gray thin or watery d/c that is “fishy” smelling = bacterial vaginosis
Definition

1. chlamydia

2. gonorrhea

3. trichomonas

4. yeast

5. bacterial vaginosis

Term
Most common cause of infertility? **
Definition

sperm

 

Tubal and pelvic pathology make up 35%

Term
essential workup for infertility **
Definition
HEST: health, eggs, sperm, tubes
Term
hormone replacement therapy increases risk of cancers only if .... **
Definition
estrogen + progestin
Term
what is "ferning" in regard to cervical fluid analysis during pregnancy?
Definition
if cervical fluid is collected and a nitrazine test is done and ferning is demonstrated, the fluid is amniotic = PROM
Term
terbutaline
Definition

a tocolytic

 

started if hx of preterm birth, positive fibronectin, short cervix, changing dilation

 

allows for corticosteroid administration for 48 hrs

Term
BP drugs to discontinue during pregnancy
Definition

ACE and ARBs

 

Term
BP > 140/90 on 2 or more occasions with no proteinuria
Definition
gestational htn
Term
Gestational trophoblastic disease:

1. non-viable pregnancy due to trophoblastic neoplasia, in very old and very young. paternal genoma 46 YY. very high hCG, hyperemesis gravidarum, uterus large for date, early pre-eclampsia. tx?

2. trophoblastic malignancy
Definition

1. hydatidiform more. tx: suction curettage, monitor hCG for 1 year

2. choriocarcinoma

Term
first trimester bleeding + cramping/knife-like one sided pelvic pain + normal/low hCG

tx
Definition

ectopic

get US

 

 

 

tx: methotrexate IM, laparotomy for rupture

Term
risk factors for placenta abruption
Definition

high parity

hypertension

hx previous abruption

Term
What level are these amenorrhea problems coming from?

Loss of GnRH
Psychological stress
Low body fat: anorexia, exercise
Congenital GnRH problems

Hyperprolactinemia
Pituitary adenoma
Hypothyroidism
Drug induced
Idiopathic
Definition

hypothalamic/pituitary level

 

Term
at what level is there a problem causing amenorrhea?

Congenital Abnormality
Primary amenorrhea due to ovarian dysgenesis, Turner’s syndrome

early menopause
Idiopathic
Secondary
Definition
ovarian
Term
intrauterine synechiae caused by infection caused by instrumentation
Definition
asherman's
Term
4 general causes of amenorrhea
Definition

hypthalamic/pituitary axis

ovarian

uterine

metabolic

Term
causes of menorrhagia
Definition

fibroids (leiomyoma)

PCOS

coagulopathy

Term
bilateral inflammation of fallopian tubes caused by STDs. can progress to tubo-ovarian abscess

presents as bilateral abd cramping, fever, leukocytosis, mucopurulent cervical d/c

cervical motion tenderness is classical finding
Definition
salpingitis - a form of PID
Term
sudden, severe, unilateral abdominal pain, maybe nausea
pt can't find comfortable position
Definition

ovarian torsion

 

tx: knee-chest position

laparoscopy

Term
causes of secondary dysmenorrhea
Definition

endometriosis

adenomyosis

leiomyoma

outflow obstruction

Term
endometrial galnds and stroma with the myometrium

sx: dysmenorrhea, menorrhagia - frequent, irregular, heavy periods

large, boggy, tender uterus

tx?
Definition

adenomyosis

 

tx: nsaids, ovarian suppression, surgery

Term
Big 3 causes of vaginitis
Definition

monilia (Candida)

trichomonas

Bacterial vaginosis (gardnerella)

Term
methods for preventing ovulation
Definition

supress gonadotropin

oral contraceptives

steroids (depo)

GnRH analogs (Lupron)

Term
ovulation testing:

1. day 3
2. day 21
Definition

day 3: estradiol (should be <80) and FSH (Should be <10)

 

day 21: progesterone should be >9

Term
Most common bone disorder in the U.S.
Implicated in 1.4 million fractures per year
Much more common in women
More common in white women than blacks
Thin more common than heavy
Bone density falls over time from peak at age 35
Men start with higher bone density
Risk factors:
Genetics
Smoking
Poor calcium intake
700 mg of Ca a day + normal diet is sufficient
Early menopause due to longer absence of estrogen
Young woman who undergoes early menopause definitely needs to be on HRT
Definition
involutional osteoporosis
Term
Alendronate (Fosamax)
Risedronate (Actonel)
Etidronate (Didronel)
Pamidronate (Aredia)
Tiludronate (Skelid)
Zoledronate (Zometa)
Definition
bisposphonates - used for osteoporosis
Term
20 y/o with ovarian cancer... what kind?
Definition
most likely germ cell - dysgerminoma or choriocarcinoma
Term
postmenopausal woman that presents with bleeding has ___ until proven otherwise
Definition
endometrial cancer
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