Term
| NKIRA binds to which receptor.. |
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Definition
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Term
| 5ht3-RA binds to which receptor.. |
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Definition
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Term
| d2ra binds to which receptor.. |
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Definition
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Term
| anti HI binds to which receptor.. |
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Definition
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Term
| bdz binds to which receptor.. |
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Definition
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Term
| thc binds to which receptor.. |
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Definition
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Term
| give all 9 classes for n/v drugs |
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Definition
| 1. anticholinergics 2. antihistamines 3. dopamine RA 4. Seratonin RA 5.Neurokinin RA 6.GABA agonist 7. cannabiboids 8. corticosteroids 9. pyridoxine |
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Term
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Definition
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Term
| antihistamines used for.. |
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Definition
| motion sickness and pregnancy |
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Term
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Definition
| chemotherapy postoperative pregnancy |
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Term
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Definition
| chemotherapy postoperative |
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Term
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Definition
| chemotherapy postoperative |
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Term
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Definition
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Term
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Definition
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Term
| corticosteroids used for.. |
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Definition
| chemotherapy postoperative |
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Term
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Definition
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Term
| SE of anticholinegics and caution |
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Definition
SE. 1 sedation 2. dry mouth 3. blurred vision Caution 1. narrow angled glaucoma 2. elderly 3. prostatic hypertrophy 3. asthma |
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Term
| SE and caution for anthistamines.. |
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Definition
se 1. sedation 2. dry mouth caution 1. elderly, narrow angled glaucoma 3. postatic hypertrophy 3. asthma |
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Term
| SE and caution for seratonin RA.. |
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Definition
SE 1.HA 2. constipation caution 1.none |
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Term
| SE and caution fo neurokinin ra.. |
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Definition
se 1. inhibits cyp 3a4 (strong inh) caution 1. watch out for drug interations |
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Term
| SE and caution for gaba agonist.. |
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Definition
SE 1. sedation 2. confusion caution 1. elderly 2. debiliated |
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Term
| SE and caution for cannabinoids.. |
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Definition
se. 1 sedation. 2 dysphoria 3. hypotension 4. dry mouth caution 1. elderly more sensitve to dysphoric effects |
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Term
| SE and caution for corticosteroids.. |
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Definition
se. 1 insomnia 2. mood change 3. hyperglycemi caution 1. diabetics |
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Term
| which drug(s) fall into this category.. give med. dose and freq of.. anticholinerigics |
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Definition
| scopolamine 1.5mg transdermal q 72hurs |
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Term
| which drug(s) fall into this category.. give med. dose and freq of antihistamines.. 5 drugs.. |
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Definition
1. benadryl 25-50mg q6h prn 2. dimenhydrinate 50-100mg q4h nte 400mg/24hrs 3. doxylamine (unison) 12.5mgtid-qidprn 4. meclizine 12.5-25mg q12h prn 5. cyclyzine(marezine) 50mg q4h prn nte 200mg/day |
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Term
| which drug(s) fall into this category.. give med. dose and freq of dopamine ra |
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Definition
1.droperidol (inapsine) IV IM 0.625mg-1.25 q6h prn 2. haloperdol (haldol) PO, IV, IM 0.5-2mg q6h prn 3. promethazine (phenergan) PO, IV, IM, PR 6.25mg-25mg q4h prn 3. prochloperazine (compazine) PO, IV, IM , PR 5-10mg q6h prn 25mg pr q12h 4. metoclopramid (reglan) 5-10mg q6h prn |
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Term
| name the drug with freq, route and dose that belongs to seratonin ra.. |
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Definition
1. dolasetron (anzimet) PO, IV 12.5-25mg iv 100mg po 2. granisetron (kytril) PO, IV 0.35-1mg IV 3. ondanesetron (zofran) 4mg iv/po q6h prn 4. palonosetron (aloxil) po iv 0.075mg IVP |
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Term
| name the drug with freq, route and dose that belongs to neuokinin ra. |
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Definition
1.aprepitant (emend) Po 40mg po w/in 3 hours prior to surgery 2. fosaprepitant (emend) IV 3 hours prior to surgery |
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Term
| name the drug with freq, route and dose that belongs to gaba agonist.. |
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Definition
1. alprazolam (xanax) po 2. ativan po iv |
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Term
| name the drug with freq, route and dose that belongs to cannabinoids.. |
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Definition
1. dronabinol (marinol) po 2. nabilone (cesamet) po |
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Term
| name the drug with freq, route and dose that belongs to corticosteroids.. |
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Definition
1. dexamethason iv. po 2. methylprednisilone |
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Term
| name the drug with freq, route and dose that belongs to pyridoxine |
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Definition
| vitamin b6 po 10-25mg po tid-qid |
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Term
| name the neurotransmiters that may effect n/v |
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Definition
| 1. substrate p 2. serotonin 3. dopamin 4. histamine 5. acetycholine 6. gaba 7. cannabinoid 8 endorphine |
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Term
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Definition
P6 accupressure non invasive $10 3 finger breadths up from the wrist fold between the 2 large tendons |
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Term
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Definition
acustimulation non invasive electrical stimulation $130 3 finger breadths up from the wrist fold between the 2 large tendons |
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Term
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Definition
| invasive requires prof placement $50-100 |
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Term
| MOA, Inications, of Ginger |
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Definition
MOA: blocks 5ht3 receptors in vitro indications: motion sickness (possibly ineffective) and nvp (possibly effectiv) |
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Term
| side effects and drug interactions of ginger |
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Definition
side effects. 1 gi upset 2. heartburn 3. bleching 4. diarrhea 5. mouth/throat irritation **appears to be safe in pregnant women) Drug interactions 1. possible coumarin anticoagulatn |
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Term
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Definition
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Term
| moa of german chamomile.. |
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Definition
| anti- inflammatory activity |
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Term
| Caution of red raspberry leaf.. |
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Definition
| may cause uterus to contract, used to facilitate delivery ** avoid using during pregnancy** |
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Term
| name 3 antibiotics that may cause n/v |
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Definition
1. imipenem
2. metronidazole
3.augmentin |
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Term
| other therapeutic agents that my cause n/v.. |
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Definition
| 1. digoxin 2. theophylline 3. estrogen |
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Term
| The critical neurotransmitters involved in the production of motion sickness appear to be.. |
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Definition
| 1. histamine 2. acetylcholine 3. norepinephrine |
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Term
| risk factors for motion sickness |
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Definition
1. f>m
2. age 2-12
3. hormones (pregnant)
4. other illness (migraine,labyrinthitis)
5. type of motion and body position |
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Term
| s and sx of motion sickness.. |
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Definition
1. nausea
2. dizziness
3. belching
4. increase salavation
5. warmth
6. diaphorsis
7. feeling of malaise
8. hyperventilation
9. pallor (pale) |
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Term
| which meds are safe for pregnant women.. |
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Definition
| 1. meclizine, diphenhydramine,dimenhydrinate, prochlorperazine |
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Term
| which meds are safe in pediatrics.. |
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Definition
1. diphenhydramine 2.dimenhydrinate
3. cyclizine |
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Term
| out of these four, rank them from least to most sedating. 1 scopolamine,meclizine,lorazepam,promethazine |
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Definition
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Term
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Definition
1. anesthetic agents
2. opiods administered during or after surgery 3. surgerical procedure itself |
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Term
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Definition
1. f>m
2. non smoker(induce cyp450)
3. age (3-14)
4.hx of ponv
hx of motion sicknes
5. duration of surgery
6.anethesia inhaled>IV |
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Term
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Definition
1. 5ht3-ra
2. anticholinergics
3. dexamethasone
4.nk1-ra
5.d2-ra
6.epinephrine
7. accupressure |
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Term
| how many risk factors do you need to be considered low risk and how do you treat it? |
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Definition
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Term
| how many risk factors do you need to be considered mod risk and how do you treat it? |
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Definition
1-2 RF
prophylaxis with one or more afents from diff classes |
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Term
| how many risk factors do you need to be considered high risk and how do you treat it? |
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Definition
3-4 rf
prophylaxis with 2 or more agents from diff classes |
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Term
| what is the ponv rescue tx? |
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Definition
1. if no ponv prophylaxis was used start with 5ht3-ra
2. if ponv prophylaxis was used , start with agent from diff pharm class |
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Term
| what is hyperemesis gravidarum? |
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Definition
| severe form of nvp (nausea and vomiting of pregnancy) |
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Term
| pharm tx for nvp (4 agents) |
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Definition
in this order.. 1 vit b6 25mg q8h 2. doxylamine 12.5mg q6-8hrs
3. promethazine 12.5-25mg po/pr q4h 4. dimehydrinate 50-100mg q6h nte 200mg/day |
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