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NURS366
Common Lab Values
93
Nursing
Undergraduate 3
01/29/2012

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Term
4 Purposes of lab Data for diagnosis
Definition
-reveals problems not visible during assessment
-determines stage of diseases
-estimates the activity of the disease process
-measures effet of therapy
Term
What is in a CBC?
Definition
-RBC
-hemoglobin
hematocrit
wbc
wbc differential
platelet count
MCV
MCH
MCHC
RDW
Term
Why is I&O done?
Definition
Input and output. Test that gives ideas of bodies fluid balance. Not the most accurate measure of fluid status.
Term
How much of body water is intracellular vs. extrcellular?
Definition
intracellular- 2/3 of body water
extracellular is 1/3 of body water
Term
anion vs. cation
Definition
anion = negative charge
cation = positive charge
Term
What are extracellular electrolytes?
Definition
exert their effects outside the cell
Term
What are intracellular electrolytes?
Definition
Work inside the cell
Term
four examples of extracellular electrolytes
Definition
sodium, chloride, clacium, bicarbonate
Term
three examples of intracellular electrolytes
Definition
potassium, phosphate, magnesium
Term
Two ways of measuring electrolytes?
Definition
when measure in milligrams per deciliter mg/dl or in milliequivalent mEq/L
Term
Two electrolytes measured in milligrams per deciliter?
Definition
calcium
phosphates
Term
Four electrolytes measured in milliequivalent mEq/L
Definition
sodium, potassium, magnesium, chloride
Term
Normal serum concentration of Sodium?
Definition
135 -145 mEq/;
Term
What is chief electrolyte of ECF?
Definition
Sodium
Term
Sodium, anion or cation?
Definition
cation
Term
What are the two roles of sodium?
Definition
-maintains water balance throughout body
-participates in the generation of transmission of nerve impulses
Term
What is Hyponatremia?
Definition
Less than 135 mEq/L
Term
4 causes of hyponatremia
Definition
medications
inadequate sodium intake
water gain
sodium loss
Term
8 signs and symptoms of hyponatremia?
Definition
-Abdominal cramps
-headaches
-Nausea
-Seizures
-Muscle twitching
-Altered level of consciousness (lethargy or confusion)7
Term
How to test for hyponatremia during assessment?
Definition
skin with decreased turgor remains elevated after being pulled up and released
Term
Abnormal hypernatremia value
Definition
value greater than 145 mEq/l
Term
a high sodium level, greater than 145 mEq/L, two causes?
Definition
water deficit
Excessive sodium intake or gain
Term
How to evaluate edema?
Definition
do pitting test. press finger tip firmly into skin of bony prominance for a few seconds then note the depth of the imprint your finger leaves on the skin. Slight imprint indicates +1 pitting, deep imprint with skin slow to return to original indicates +4 pitting edema.
Term
Signs and symptoms of hypernatremia
Definition
plyuria
anorexia
vomitting
weakness
agitiaton and restlessness
confusion
dry and flushed skin
thirst
lethargy
tachycarida
fever
Term
Potassium, cation or anion?
Definition
cation
Term
normal serum concentration of potassium?
Definition
3.5-5.0 mEq/L
Term
What is chief electrolyte of ICF?
Definition
Potassium
Term
What 3 things do potassium's serum concentration levels depend on?
Definition
Aldosterone
sodium reabsorption (as sodium is reabsorved K+ is lost.
Acid Base Balance
Term
Potassium in important in (three processes)
Definition
Protein and Carbohydrate metabolism
Cellular building
Transmission of electrical impuslses
Term
Hypokalemia values?
Definition
less than 3.5 mEq/L
Term
4 causes of hypokalemia
Definition
-inadequate intake
-excretion or loss of potassium exceeding intake
Surgery
Alcoholism
Term
1 major sign and symptom of hypokalemia
Definition
Abnormal EKG (prolonged PR interval, ST depression)
Term
Lab Values of hyperkalemia?
Definition
Greater than 5 mEq/L
Term
6 causes of hyperkalemia
Definition
-acute and chronic renal failure
excessive release from cells secondary to traumatic injury, severe infection or burn
Excessive infusion of IV solutions that contain K+ or excessive oral intake
Acidosis
Medications
Fast Growing Cancers
Term
5 signs and symptoms of hyperkalemia
Definition
hypotension
irregular heart rate
paresthesia
convulsions
cardiac arrest
Term
Normal calcium values
Definition
9.0-10.5 mg/dL
Term
Hypocalcemia
Definition
less than 9.0mg/dL common in the elderly
Term
Distribution of Calcium throughout body
Definition
99% found in bone
remaining one percent is albumin bound, ionized or in other anion complexes
Term
hypercalcemia
Definition
greater than 11mg/dl
Term
What 3 kinds of patients would commonly have hypercalcemia?
Definition
metastatic malignancy (lung breast ovary, prostate)
hyperparathyroidism
Thiazide diuretic therapy
Term
Normal Magnesium values
Definition
1.3-2.1 mEq/L
Term
Magnesium distribution throughout the body
Definition
1% in blood
49% intracellular
50% bone
most bound to ATP
Term
Hypomagnesium
Definition
increased cardiac irritability aggravate cardiac arrhythmias
Term
Hypermagnesium
Definition
retards neuromuscular conduction and causes respiratory depression
Term
What is PT?
Definition
Prothrombin Time
Term
Normal Prothrombin Time?
Definition
11-12.5 seconds
Term
INR (International normalized ratio)
Definition
stands for a way of standarizing the results of prothrombin time tests, no matter the testing method)
Term
What is PTT?
Definition
Partial Thromboplastim Time
Term
What is normal PTT
Definition
60-70 seconds
Term
What is Hemoglobin?
Definition
a protein in RBC that carries oxygen- test is done to determine oxygen carrying capacity in blood
Term
Normal Hemoglobin
Definition
14-18gm/dL
Term
Three characteristics of low hemoglobin levels?
Definition
anemia/bleeding
overhydration
Bone marrow supression
Term
Three characteristics of high hemoglobin levels
Definition
dehydration
polycythemia cera
pulmonary fibrosis
Term
What is Hematocrit
Definition
measures the percentage of RBC found in whole blood.
Term
Normal hematocrit values
Definition
42-52% expressed s total percentage of blood volume composed of RBC
Term
four characteristics of low hematocrit levels?
Definition
overhydration
anemia
bleeding
bone marrow suppression
Term
Two characteristics of high hematocrit levels?
Definition
dehydration
polycythemia vera
Term
Blood Urea Nitrogen
Definition
Urea nitrogen is what forms when protein breaks down.
Term
Normal blood urea nitrogen value
Definition
7-20 mg/dl
Term
Four characteristics of low BUN levels
Definition
liver failure
low protein diet
malnutrition
overhydration
Term
8 characteristics of high BUN values
Definition
CHF
excessive protein levels
GI bleeding
Hypovolemia
Kidney disease
kidney fialure
UTI
Shock
Term
What is Creatinine?
Definition
Waste product produced in your muscles from the breakdown of creatine. test used to diagnose imparied kidney function and to determine renal damage.
Term
Three causes of elevated creatinine test values?
Definition
Diets high in meat
Heavy metal chemotherapy
Cephalosporins
Term
NOrmal Creatine levels
Definition
.5-1.1 mg/dl
Term
People that commonly have low Creatinine values (3)
Definition
elderly
muscular dystrophy paralysis
Term
characteristic of high creatinine values
Definition
impaired renal function
Term
Glucose, formed by? and stored in?
Definition
formed by digesting carbohydrates store in the liver as glycogen
Term
Normal fasting glucose levels
Definition
60-100 mg/dl
Term
Glucose test is used for screening for three problems?
Definition
diabetes
gesttational diabetes
Hypoglycemia
Term
Phosphorus normal job (3)
Definition
maintains ph of bodily fluid
maintains cellular osmotic pressure
important component of DNA and RNA
Term
how is absorpotion of phosphorus facilitated?
Definition
by vitamin D
Term
normal phosphorus level?
Definition
2.4-4.1 mg/dl
Term
How are phosphorus levels controlled
Definition
by intake and renal fucntion
Term
how does kidney failure afffect phosphorus levels and calcium levels
Definition
hyperphosphatemia and hypocalcemia
Term
What happens during bone demineralization
Definition
hypocalcemia
Term
What mineral has inverse proportionate relationship to calcium?
Definition
phosphorus
Term
What is a liver profile
Definition
seven tests used to evaluate the liver for injury, infection adn inflammation
Term
normal platelet values
Definition
15,000 to 450,000 platlets per microliter of blood
Term
How do you evaluate platelet levels?
Definition
order a CBC
Term
Normal WBC levels?
Definition
4,500-10,000 per microliter of blood
Term
Normal differential WBC levels
Definition
Basophils = .5-1%
Eosinophils 1-4%
Lymphocytes 20-40%
Monocytes 2-8%
Neutrophils 40-60%
Term
Where are RBC produced and in response to what?
Definition
produced in bone marrow in response to blood oxygen levels
Term
Normal RBC count?
Definition
4.7-6.1 million per microliter of blood
Term
7 things that urinalysis are used to look at?
Definition
(Used to diagnosis, evaluate and screen)
sepcific gravity
ph
glucose
protein
ketones
blood
nitrate
Term
leukopenia?
Definition
decrease in number of white blood cells.
Term
Leukocytosis
Definition
raised white blood cell count
Term
thrombocytosis
Definition
high platelet count in blood
Term
Thrombocytopenia
Definition
low platelet count in blood
Term
CMP
Definition
Comprehensive metabolic panel. (test that measures many different electrolyte values)
Term
Two factors that determine fluid balance ( and what area of the body they occur through)
Definition
insensible fluid loss (occurs through skin and lungs)
Sensible fluid loss (urination, defecation, wounds)
Term
What is the most accurate measure of fluid status?
Definition
daily weight
Term
what anion usually accompanies sodium
Definition
chloride
Term
as sodium is reabsorbed, ___ is lost
Definition
potassium K (in sodium potassium pump)
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