Shared Flashcard Set

Details

NSAIDS
Non-opioid pain meds
18
Pharmacology
Graduate
06/12/2011

Additional Pharmacology Flashcards

 


 

Cards

Term
Acetaminophen
Definition
Block prostaglandin synthesis, similar to ASA
Term
Acetaminophen
Definition
Acetaminophen may cause hepatic damage especially with long term used and EtOH
Term
No GI effects
No heme effects
No assoc. with Reye Syndrome
No CV affects
No resp effects
No acid-base effects
Definition
How Acetaminophen is different from ASA
Term
Aspirin
Definition
Blocks COX-1 and COX-2; inhibits COX-1 better; can induce asthma
Term
ASA
Definition
Prevention of thrombus post MI, CVA, men >45 and Women>55
Term
ASA
Definition
Metab via conjugation at low to moderate doses; excreted by kidneys at high doses
Term
ASA
Definition
Major side effect is gastric bleeding
Term
ASA
Definition
Can displace warfarin, methotrexate, sulfonamides
Term
Definition
Low doses inc CO2, inc acidity; toxic doses cause metabolic acidosis and hypokalemia
Term
ASA
Definition
In overdose of this, increased alkalinity of urine with sodium bicarb
Term
Celecoxib
Definition
A selective COX-2 inhibitor
Term
Celecoxib
Definition
Used in Osteoarthritis, RA, FAP
Term
Celecoxib
Definition
May show inc risk of MI
Term
Celecoxib
Definition
May inhib 2D6 in some people, i.e. may slow metab of tricyclics, SSRIs, antiarrhythmics
Term
Ibuprofen
Definition
An NSAID that does not displace warfarin
Term
Ibuprofen
Definition
Can block effects of ASA
Term
Ibuprofen
Definition
Chronic use may inc risk of MI
Term
Naproxen
Definition
Chronic use assoc w/ more ulcer risk than other NSAIDS
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