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NSAIDS
Exam II
21
Pharmacology
Professional
01/07/2013

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Term
Which drug is irreversibly inhibiting synthesis of prostaglandins, cross BBB and placenta, use for analgesia, antipyretic, antiinflammatory, antiplatelet?
Definition
Aspirin
Term
What drugs have toxicity like increase uric acid levels, not used in last trimester of pregnancy, Reye's syndrome, Slicylism?
Definition
Aspirin
Term
What is indication of Aspirin in low dose, intermediate dose and high dose?
Definition
low dose is anti-platelet( inhibits prosta to thromboxane A2)
intermediate dose is antipyretic/analgesis (inhibit prostag to fever)
Highdose is anti-inflammatory (inhibit prosta)
Term
What drug is good to used for children for analgesia, antipyretic and inhibits prostag synthsis in CNS?
Definition
Acetaminophen
Term
Which drug is reversible inhibited of Cox used for analgesic, antipyretic, antiinflammaroty, good for children, anti-platelet w/cont use?
Definition
Ibuprofen
Term
Which drug is derivative of salicylic acid, but not hydrolyzed to salicylate, reversibly inhibits Cox I and II, used for analgesis, anti-inflammatory, weak antipyretic?
Definition
Diflusinal
Term
Which drug is derivative from acetic acid, reversible inhibit of Cox 1 and 2, not for children <14, headache, depression, hypersensitivity?
Definition
Indomethacin
Term
Which drug is reversible inhibition of Cox 1 &2?
Definition
Ketorolac
Term
Which NSAIDS is derive from Propionic acids?
Definition
Ibuprofen
Ketoprofen
Naproxen
Flubiprofen
Fenoprofen
Oxaprozin
Term
Which NSAIDS is derived from Oxicams?
Definition
Piroxicam
Term
Which NSAIDS is derived from Acetic acids?
Definition
Indomethacin
Diclofenac
Etodolac
Sulindac
Tolmetin
Term
Which drug is derived from Naphthylakalones?
Definition
Nabumetone
Term
Which NSAIDS drug is given one aday?
Definition
Oxicams/Piroxicam
Term
Which NSAIDS drug is given fro gout?
Definition
Indomethacin
Term
WHich NSAIDS drug is given for topical on skin?
Definition
Diclofenac
Term
Which NSAIDS drugs is given for less GI and renal problems?
Definition
Sulindac and Nabumetone
Term
Which is the only NSAID drug give headache as the size effect?
Definition
Indomethacin
Term
What is the main complication of NSAIDS?
Definition
Prexisting Asthma
Term
Which NSAIDS drug is used mainly as analgesic not as antiinflammatory, used to replace morphine in certain situation in management of postoperative pain, and long term used leads to peptic ulcers?
Definition
Ketorolac
Term
Which NSAIDs drug is selective for Cox-2 inhibitors, no FDA approval, contraindicated if allergy to sulfonamides?
Definition
Celebrex (Celecoxib)
Term
Which drug is selective for Cox-2 inhibitors?
Definition
Rofecoxib
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