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NPTE Study Guide 4
NPTE Week 4 - Cardiac
257
Other
Graduate
07/31/2011

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Cards

Term
List the three layers of lining around the heart.
Definition
pericardium - outermost layer
epicardium - inner layer of pericardium
endocardium - lines inner surface & cavities of heart
Term
The RA receives blood from _____.
Definition
inferior & superior vena cava
Term
The RV is known as the ____ pressure pulmonary pump.
Definition
low
Term
The LA receives oxygenated blood from the _____.
Definition
lungs & four pulmonary veins.
Term
The LV is known as the ___ pressure systemic pump.
Definition
high
Term
T/F. The LV walls are thicker and stronger than the RV.
Definition
true
Term
Name the two A-V valves.
Definition
tricuspid (3 cusps) - right AV valve
bicuspid (2 cusps) - left AV valve
Term
The AV valves are anchored by _____ to _____ muscles. The valves close when the _____ contract.
Definition
chordae tendinae; papillary muscles
ventricles
Term
Name the two semilunar valves.
Definition
pulmonary valve - prevents backflow into R ventricle
aortic valve - prevents backflow into L ventricle
Term
Systole is the period of _____ contraction.
Definition
ventricular
Term
ESV is the amt. of blood in the ventricles after ____; usually ____.
Definition
systole, 50 mL
Term
Define diastole.
Definition
ventricular relaxation & filling of blood
Term
EDV is the amount of blood in the ventricles after _____; usually ____.
Definition
diastole; 120 mL
Term
When does atrial contraction occur?
Definition
during the last 1/3 of diastole; completes ventricular filling.
Term
List the structures supplied by the RCA.
Definition
right atrium, most of right ventricle
in most people, inferior wall of left ventricle, AV node, & bundle of His; 60% of the time supplies the SA node
Term
List the structures supplied by the LCA.
Definition
most of the left ventricle
LAD - supplies left ventricle & interventricular septum, & inferior apex & right ventricle

Circumflex - lateral & inferior walls of left ventricle & portions of left atrium - 40% of time supplies SA node
Term
The _____ sinus receives venous blood from the heart and empties it into the _____.
Definition
coronary; right atrium
Term
What does NSR stand for?
Definition
normal sinus rhythm
Term
The SA node is located at the junction of the ____ & ____.
Definition
SVC & RA
Term
T/F. SA node has parasympathetic & sympathetic innervation.
Definition
true.
Term
The AV node is located at the junction of the ___ & ___.
Definition
RA & RV.
Term
Describe the conduction of a heart beat.
Definition
origin is in the SA node - impulse spreads to both atria, which contract together

impuse stimulates AV node, transmitted down bundle of His to Purkinje fibers - impulse spreads to both ventricles, which contract together.
Term
myocardial metabolism is ____, sustained by continuous O2 delivery from the coronary arteries
Definition
aerobic
Term
myocardial tissue is ____; blood vessel walls have ____ muscle
Definition
striated; smooth
Term
Define stroke volume & list normal value.
Definition
amount of blood pumped from the LV with each myocardial contraction

55-100 mL/beat
Term
What three factors influence SV?
Definition
LVEDV (preload)
contractability
afterload - the force the LV must generate during systole to overcome aortic pressure & open aortic valve
Term
What is the Frank-Starling law?
Definition
the greater the diastolic filling, the greater the quantity of blood pumped
Term
Define CO and list normal value.
Definition
amt. of blood pumped from LV per minute.

normal is 4-5 L/min.
Term
___x____=CO
Definition
HRxSV
Term
Define cardiac index.
Definition
CO divided by body surface area

normal range is 2.5-3.5 L/min.
Term
Define LVEDP.
Definition
pressure in the L ventricle during diastole

normal range is 5-12 mm Hg
Term
EF = ___/____
Definition
SV/LVEDV
Term
What are normal values for EF?
Definition
60-70%
Term
Right atrial filling pressure is ____ during inspiration & ____ during expiration.
Definition
decreased; increased
Term
venous return is _____ when blood volume is increased.
Definition
increased.
Term
Diastolic filling rate is _____ with increased HR & heart disease.
Definition
decreased
Term
Define MVO2.
Definition
myocardial oxygen demand - energy cost to myocardium

MVO2 = HRxSBP aka RPP (rate pressure produce)
Term
Arteries transport oxygenated blood from areas of ___ to ___ pressure.
Definition
high - low
Term
___ veins accompany arteries; ____ do not.
Definition
deep; superficial
Term
venous circulation is influenced by what 4 things?
Definition
muscle contraction, gravity, respiration (increased return with inspiration), & compliancy of right heart
Term
what bodily organs are involved in the lymphatic system?
Definition
spleen, lymph nodes, tonsils, thymus, & thoracic duct
Term
lymph travels from the lymphatic capillaries to lymphatic ducts to the _____.
Definition
L subclavian vein
Term
List the major lymph nodes.
Definition
submaxillary, cervical, axillary, mesenteric, iliac, inguinal, popliteal, & cubital
Term
List the function of sympathomimetics & sympatholytics.
Definition
sympathomimetics - increase sympathetic functioning
sympatholytics - decrease sympathetic functioning
Term
Where are baroreceptors located? What do they control?
Definition
walls of aortic arch & carotid sinus
control HR
Term
List the changes to the parasympathetic & sympathetic systems, rate & force of cardiac contraction, & peripheral resistance with increased BP.
Definition
parasympathetic - stimulation
sympathetic - inhibition
decreased rate & force of contraction
decreased peripheral resistance
Term
List the changes to the sympathetic & parasympathetic systems, heart rate, BP, & peripheral resistance with a decrease in BP
Definition
sympathetic - increase
parasympathetic - decrease
HR - increase
BP - increase
peripheral resistance - increase (vasoconstriction)
Term
increased ____ causes reflex acceleration of HR.
Definition
RAP (R atrial pressure)
Term
Where are chemoreceptors located?
Definition
carotid body
Term
Increased CO2 or decreased O2, or decreased pH (increased lactic acid) results in an ____ in HR.
Definition
increase
Term
Increased O2 levels result in a ___ in HR.
Definition
decrease
Term
Increased body temp. causes an ____ in HR.
Definition
increase
Term
Define hyperkalemia and what it does to an ECG.
Definition
increased potassium - decreased rate & force of contraction

produces widened PR interval & QRS, & tall T waves
Term
Define hypokalemia & what it does to an ECG.
Definition
decreased concentration of potassium

flattened T wave, prolonged PR & QT intervals, arrythmias, could progress to V-fib
Term
Describe what hyper & hypo-calcemia do to the heart
Definition
hypocalcemia - depresses heart actions
hypercalcemia - increases heart actions
Term
Describe what increased & decreased peripheral resistance do to blood volume & blood pressure.
Definition
increased - increase blood volume & BP
decreased - decreases blood volume & BP
Term
List the value for an impaired fasting blood glucose level.
Definition
<126 mg/dL
Term
List when obesity & waist girth measurements become a risk factor.
Definition
BMI >30 kg/m
waist girth >100 cm
Term
What is an ideal level for HDL cholesterol?
Definition
>60 mg/dL
Term
How long should you palpate for a regular vs. irregular rhythm to obtain a pulse?
Definition
regular - 30 sec.
irregular - 1-2 minutes
Term
Describe finding an apical pulse.
Definition
Pt. in supine - 5th intercostal space, midclavicular vertical line (apex of heart) - could be displaced laterally by CHF, cardiomyopathy, or ischemic heart disease

could be displaced upwards by high diaphragm or pregnancy
Term
Where do you palpate for the carotid artery? Why can you not palpate B/L?
Definition
on anterior neck between SCM & trachea
palpating bilaterally causes bradycardia secondary to stimulation of carotid sinus baroreceptors which produces a reflex drop in pulse rate or BP
Term
Where do you palpate for the brachial artery?
Definition
medial to antecubital fossa
Term
When palpating the popliteal artery, what position should the knee be in?
Definition
slightly flexed
Term
List normal adult HR, BP, RR, & SaO2.
Definition
70 bpm (60-80)
120/80
12-20
96-100
Term
List normal pediatric HR, BP, RR, & SaO2.
Definition
120 bpm (70-170)
<2 yrs 106-110/59-63
3-5 113-116/67-74
30-60 breaths/min
96-100%
Term
Define tachycardia & bradycardia.
Definition
>100 bpm or <60 bpm
Term
List the causes of a weak, thready pulse.
Definition
low stroke volume, cardiogenic shock
Term
List the causes of a bounding, full pulse.
Definition
shortened ventricular systole & decreased peripheral pressure or aortic insufficiency
Term
Where would you place the stethoscope if you wanted to locate the following heart landmarks: aortic valve, pulmonary valve, tricuspid valve, mitral valve.
Definition
aortic valve: R 2nd IC space at sternal border
pulmonary valve: L 2nd IC space at sternal border
tricuspid: L 4th IC space at sternal border
bicuspid L 5th IC space at midclavicular line
Term
What is the S1 & S2 heart sounds? When are they decreased?
Definition
S1 - closing of tricuspid & mitral valves
S2 - closing of aortic & pulmonary valves

S1 decreased with a first-degree heart block
S2 decreased with aortic stenosis
Term
Define a systolic & diastolic murmur
Definition
systolic - falls between S1 & 2 - may indicate valvular disease

diastolic - falls between S2 & S1 - usually indicates valvular disease
Term
Describe the grades of heart murmurs.
Definition
Grade 1 is softest audible murmur to murmur audible with stethoscope off the chest
Term
Define "thrill".
Definition
an abnormal tremor accompanying a vascular or cardiac murmur; felt on palpation
Term
Define bruit.
Definition
an adventitious sound or murmur (blowing sound) of arterial or venous origin; common in carotid or femoral arteries; indicative of atherosclerosis
Term
Define Gallop rhythm.
Definition
abnormal heart rhythm with three sounds in each cycle, resembles the gallop of a horse

S3 - associated with ventricular filling - occurs soon after S2 - could be indicative of CHF of LV in older adults

S4 - associated with atrial contraction & ventricular filling - occurs just before S1 - indicative of pathology (CAD, MI, aortic stenosis, or chronic hypertension)
Term
Define the P wave, P-R interval, & QRS segment.
Definition
P wave - atrial depolarization
P-R interval - time required for impulse to travel from the atria to the Purkinje fibers
QRS segment - ventricular depolarization
Term
Define the S-T segment, the T wave, and the QT interval.
Definition
S-T segment - beginning of ventricular repolarization
T wave - ventricular repolarization
Q-T interval - time for electrical systole
Term
How do you calculate heart rate from an ECG?
Definition
count the number of intervals between QRS complexes in a 6 second strip & multiply by 10
Term
What is affected with ventricular arrythmias?
Definition
CO adversely affected - pulseless situation - requires CPR, defibrillation, medication
Term
Define PVC's. What does it look like on a ECG?
Definition
premature beat arising from the ventricle - on ECG - no P wave - bizarre and wide QRS that is premature, followed by a long compensatory pulse

Serious PVC's are greater than 6/min. or a very early PVC (R on T phenomena)
Term
Define V-tach.
Definition
ventricular tachycardia: a run of 3 or more PVC's occuring sequentially at a very rapid rate

usually the result of an ischemic ventricle
Term
Define V-fib and what it looks like on an ECG.
Definition
chaotic activity of ventricle originating from multiple foci - unable to determine rate. On ECG: bizarre, erratic activity without QRS complexes - clinical death within 4-6 minutes - no effective CO.
Term
Define atrial arrythmias & describe what it looks like on ECG.
Definition
rapid & repetitive firing of 1 or more ectopic foci in the atria

On ECG, p wave is abnormal or not identifiable

CO is maintained - could precipitate ventricular failure

HR rapid with atrial tachycardia - 140-250 bpm
atrial flutter - 250-350 bpm
Term
Which A-V block is life-threatening?
Definition
third-degree, complete block - requires medications (atropine) & surgical implantation of pacemaker
Term
With impaired coronary artery perfusion (ischemia or injury) the ____ segment becomes depressed.
Definition
S-T - can be upsloping, downsloping, or horizontal
Term
List the 3 possible ECG mechanisms for an MI.
Definition
increased Q wave
T wave inverted
ST elevated
Term
Describe what Hyperkalemia & Hypokalemia do to an ECG.
Definition
Hyperkalemia: widens QRS, flattens P, T becomes peaked

Hypokalemia - flattens T wave, produces a U wave
Term
Describe what happens to an ECG from Hypercalcemia & Hypocalcemia.
Definition
Hyper - widens QRS, shortens QT
Hypo - prolongs QT interval
Term
Describe how hypothermia changes an ECG.
Definition
elevates ST segment, slows rhythm
Term
Describe what digitalis does to an ECG reading.
Definition
depresses ST segment, flattens T wave (or inverts), QT shortens
Term
Describe what Quinidine does to an ECG.
Definition
QT lengthens, T wave flattens, QRS lengthens
Term
Describe what beta blockers do to an ECG.
Definition
decreases HR, blunts HR response to exercise
Term
What is the purpose of nitrates?
Definition
increase HR
Term
Describe what antiarrhythmic agents do to an ECG.
Definition
can prolong QRS & QT intervals
Term
List the values for prehypertension, & the 3 stages of hypertension.
Definition
Prehypertension: systolic = 120-130; diastolic = 80-89
Stage I: systolic 130-140; diastolic 90-100
Stage II: systolic 140-160; diastolic 100-110
Stage III: systolic >160; diastolic >110
Term
Differentiate between primary & secondary hypertension.
Definition
primary - no identifiable cause
secondary - cause is determined.
Term
List the procedure for taking orthostatic BP measurements.
Definition
Pt. in supine for at least 5 min. Take a BP in supine.
Repeat BP at 1 min. & 3 min. after patient moves into standing or sitting position.

Drop of systolic BP of more than 20 mm Hg or standing BP less than 100 mm Hg is significant
Term
Define MAP.
Definition

arterial pressure within the large arteries over time, dependent on mean blood flow & arterial compliance. MAP = (SBP + 2DBP)/3

or

MAP = DBP + 1/3PP

where PP = SBP-DBP

Term
Define tachypnea & hyperpnea.
Definition
tachypnea: an increase in rate of breathing >20 breaths/min.

hyperpnea: increase in depth & rate of breathing
Term
What does PND stand for?
Definition
paroxsymal nocturnal dyspnea
Term
Crackles may be due to _____.
Definition
lung secretions
Term
Define hypoxemia.
Definition
O2 sat below 90%
Term
Define clubbing.
Definition
curvature of the fingernails with soft tissue enlargement at the base of the nail: associated with chronic oxygen deficiency & heart failure
Term
Trophic changes of the skin are associated with which heart condition?
Definition
PVD.
Term
Define Stemmer's sign.
Definition
dorsal skin folds of the toes or fingers are resistant to lifting; indicative of fibrotic changes & lymphadema
Term
IC with pain, cramping & fatigue occurring during exercise & relieved by rest is associated with ____.
Definition
PVD
Term
IC is related to _____ insufficiency.
Definition
arterial
Term
Why should you examine the venous system before the arterial?
Definition
venous insufficiency can validate some tests
Term
Describe the percussion test.
Definition
in standing, palpate one segment of greater saphenous vein while percussing vein approximately 20 cm. higher - if a pulse wave is felt by the lower hand, the intervening valves are incompetent.
Term
Describe Trendelenberg's test.
Definition
Tests retrograde filling - determines competence of communicating veins & saphenous system

Pt. in trendelenberg position (legs elevated) to empty venous blood

tourniquet placed on proximal thigh

Pt. asked to stand

note if veins fill in normal pattern - should take approx. 30 sec.
Term
What is considered "delayed filling" for venous insufficiency with the venous filling time test?
Definition
>15 sec.
Term
Describe teh air plethysmography (APG) test.
Definition
pneumatic device calibrated to measure patency of venous system; volume

cuff is inflated around the calf & is attached to a pressure transducer & microprocessor

occludes venous return & permits arterial inflow; recorder registers increasing volume with cuff; time to return to baseline with cuff deflation
Term
What is the ABI?
Definition
BP LE/BP UE

1.0 - normal
.8-1 - mild PAD
.5-.8 - moderate PAD, IC, compression therapy contraindicated
<.5 - severe PAD, + for IC at rest, compression therapy contraindicated
Term
List the grading scale for pulses.
Definition
0 - absent
1+ - diminished, barely perceptible
2+ - normal, easily palpated
3+ - full pulse, increased strength
4+ - bounding
Term
List the grading scale for edema.
Definition
1+ - mild, barely perceptible indentation
2+ - moderate, easily identified impression; returns to normal within 15 sec. - up to 1/2 in. of pitting
3+ - severe - depression takes 15-30 seconds to rebound - 1/2 to 1 in. pitting
4+ - very severe, depression lasts >30 sec with >1 in. pitting
Term
List & describe the 3 tests used in myocardial perfusion imaging.
Definition
Thallium-201 scan: tallium is injected into blood via IV; radioisotopes concentrate in normal tissue but not in ischemic or infarcted tissues (cold spots)

Thallium stress test - used with an exercise test - injected at peak exercise

PET scan - uses radioactive markers (18F-fluoredeoxyglucose (FDG))
Term
Describe a Swan-Ganz Catheter.
Definition
a.k.a. pulmonary artery catheter - inserted into large vein - often internal jugular, subclavian, or femoral vein - threaded into RA, RV, & into pulmonary artery - measures CVP, pulmonary artery pressure (PA), pulmonary capillary wedge pressures (PWCP) - catheter can provide an indirect measurement of the pressure in the left atrium of the heart & LVEDP
Term
List the enzyme changes associated with myocardial infarction.
Definition
Elevations in SGOT (serum-glutamic-oxaloacetic transaminase) - peaks at 24-48 hours

Elevations in CPK - serum creatine phosphokinase - peaks at 24 hours

Elevations in CK-MG - peaks at 12-24 hours

Elevations in LDH (serum lactate dehydrogenase) - peaks at 3-6 days
Term
List normal PaO2 & PaCO2 values, and their clinical significance.
Definition
PaO2 - 80-100 mm Hg
PaCO2 - 35-45 mm Hg

PaO2 - increased in hyperventilation; decreased in cardiac decompensation, COPD, & some neuromuscular disorders

PaCO2 - increased in COPD; decreased in pregnancy, pulmonary embolism, & anxiety
Term
List the normal values for blood pH & the clinical significance.
Definition
7.35-7.45
decreased in Respiratory acidosis; COPD, respiratory depressants, myasthenia

increased in Respiratory alkalosis; hyperventilation, sepsis, liver disease, fever

decreased in Metabolic acidosis: increased acidic intake - alcohol, loss of alkaline body fluids, renal failure

Increased in Metabolic Alkalosis; vomiting, potassium depletion, diuretics, volume depletion
Term
List normal values for PT, PTT, INR, & bleeding time & list clinical significance of each.
Definition
PT - 11-15 sec. (clotting); prolonged in deficiencies of factor X, hemorrhagic disease, cirrhosis, hepatitis drugs; if 2.5x greater than normal, PT contraindicated

PTT (partial thromboplastin time) - 25-40 seconds; increased if there's a deficiency of factor VIII, IX, & X

INR (international normalized ratio) - ratio of PT to reference range; .9-1.1; INR <2 desirable; >2 - consult with M.D. for increased risk of bleeding; INR >3 - increased risk of hemorrhage

Bleeding time: 2-10 minutes; increased in platelet disorders, thrombocytopenia
Term
List normal values & clinical significance of WBC's, RBC's, & erythrocyte sedimentation rate.
Definition
WBC: 5-10,000; increased with infection & corticosteroids; decreased in aplastic anemia, B12 or folate deficiency - >5000 (light ex. only); <5000 w/ fever ex. contraindicated; <1,000 use mask & standard precautions

RBC's: males 4.7-6.1 x10^6/mm^3
females: 4.2-5.4 x10^6/mm^3; increased with polycythemia, decreased in anemia

ESR: males up to 15 mm/hr
females up to 20 mm/hr; increased with infection & inflammation: rheumatic or pelvic inflammatory disease, osteomyelitis; used to monitor effects of treatment (RA, SLE, Hodgkin's disease)
Term
List the normal values & clinical significance of Hematocrit, Hemoglobin, Platelet count, & fibrinogen.
Definition
Hct: Male 42-52%; Female 37-47% - increases in erthryocytosis, dehydration, & shock
decreases in severe anemias & acute hemorrhage
>25% but less than normal: light ex. only
<25% ex. contraindicated

Hgb: Males 14-18 g/dL; Females 12-16 g/dL
low values result in decreased exercise tolerance, increased fatigue, & tachycardia - light only (8-10)
<8 g/dL - ex. contraindicated

Platelets: 150,000-450,000 cells/mm^3
increased in chronic leukemia, hemoconcentration, decreased in cancer chemotherapy
<20,000 - AROM, ADL's only
20,000-30,000: light only
30-40,000 - moderate exercise

Fibrinogen, plasma
175-433 mg/dL; increased in inflammatory states, pregnancy, oral contraceptives
decreased in cirrhosis, hereditary diseases
Term
List desirable and high risk cholesterol & triglycerides values.
Definition
desirable <200 mg/dL; borderline 200-230; high risk >240

HDL: low risk >60; mod risk 35-60; high risk <35

LDL: >100 with multiple risk factors; >160 for low risk individuals

Trigylcerides <165 desirable

LDL/HDL ratio: low risk .5-3.0, mod risk 3.0-6.0, high >6.0
Term
Define Levine's sign.
Definition
patient clenches fist over chest with angina.
Term
Describe the possible causes of angina.
Definition
increased demands on the heart
vasospasm, symptoms may be present at rest
Term
Differentiate between Stable & unstable angina.
Definition
stable - classic exertional angina; occurs at a predictable rate-pressure product, RPP (HRxBP)

unstable angina - coronary insufficiency with risk for MI or sudden death - pain is difficult to control without any predictable RPP
Term
List & describe the 3 zones of infarction with an MI.
Definition
central zone - consists of necrotic, noncontractile tissue - electrically inert - see pathologic Q wave

zone of injury - area immediately adjacent to central zone - tissue is non-contractile, cells undergoing metabolic changes - electrically unstable - on ECG, see elevated ST segments in leads of injured area

zone of ischemia: outer area, cells also undergoing metabolic changes, electrically unstable - on ECG, see T wave inversion
Term
Differentiate between transmural & nontransmural (non Q wave infarctions)
Definition
Transmural = full thickness of myocardium
Non-transmural - subendocardial, subepicardial, intramural infarctions
Term
An inferior MI is in the _____ & causes disturbances of the upper conduction system - caused by a blockage in the ____.
Definition
right ventricle; RCA
Term
A lateral MI causes damage in the _____ & is caused by damage to the _____ artery.
Definition
ventricular ectopy
circumflex artery
Term
An anterior MI causes damage to the _____ & is a result of damage to the _____ artery.
Definition
lower conduction system; LAD
Term
Impaired ventricular function results in _____ SV, ____ CO, ____ EF, & ____ end diastolic ventricular pressure.
Definition
decreased, decreased, decreased, & increased
Term
Describe what happens with R heart failure.
Definition
blood is not adequately returned from the systemic circulation to the heart - causes peripheral edema, weight gain, venous stasis, nausea, & anorexia
Term
Describe what happens with L sided heart failure.
Definition
increased pulmonary artery pressures & pulmonary edema
pulmonary signs & symptoms: cough, dypsnea, orthopnea, weakness, fatigue
Term
decreased CO results in pre-failure of what organ?
Definition
kidneys
Term
Anorexiaa, Weight gain, ascites, increase in RAP, CVP, jugular venous distention, + hepatojugular reflex, & murmur of tricuspid insufficiency are all signs of what sided heart failure?
Definition
R
Term
cough, SOB, DOE, paroxysmal nocturnal dypsnea, crackles, pulsus alterans, decreased urine output, Cheyne stokes respirations, & murmur of mitral insufficiency are all known characteristics of ___ sided heart failure
Definition
L
Term
List the actions of nitrates.
Definition
decrease preload through peripheral vasodilation, reduce myocardial oxygen demand, reduce chest discomfort, & may also dilate coronary arteries & increase coronary blood flow
Term
List the actions of beta blockers.
Definition
decrease myocardial demand by decreasing HR & contractility, control arrhythmias, & reduce BP
Term
List the actions of calcium channel blocking agents.
Definition
inhibit flow of calcium ions - decreases HR, contractility, dilates coronary arteries, reduces BP, controls arrhythmias & CP
Term
List the actions of antiarrhythmics
Definition
restores normal heart rhythm, improve CO
Term
List the actions of antihypertensives.
Definition
control hypertension - goal is to maintain a diastolic pressure <90 mm Hg - decreases afterload, reduces myocardial oxygen demand
Term
List the actions of digitalis.
Definition
increases contractility & decreases HR; mainstay in tx of CHF
Term
List the actions of diuretics.
Definition
decreases myocardial work, controls hypertension
Term
List the actions of aspirin
Definition
decreases platelet aggregation, may prevent MI
Term
List the action of tranquilizers.
Definition
decrease anxiety, sympathetic effects
Term
List the actions of hypolipidemic agents.
Definition
reduces serum lipid levels when diet & weight reduction are not effective
Term
List examples of beta blockers.
Definition
popranolol (Inderal)
Term
List examples of calcium channel blocking agents.
Definition
diltiazem (cardizem, Procardia)
Term
List examples of anti-arrhythmics.
Definition
quinidine, procainamide
Term
List examples of antihypertensives
Definition
propanolol, reserpine
Term
List examples of diuretics.
Definition
Lasix, furosemide, hydrocholorothiazide, Esidrix
Term
LIst examples of hypolipidemic agents.
Definition
cholestyramine (Questram, colestipol (Colestid), simvastatin (Zocor), & lovastatin (Mevacor)
Term
Differentiate between heterotopic & orthotopic heart transplantation.
Definition
heterotopic - original heart left - donor heart used to piggy back of original heart

orthotopic - remove disease heart & replase with donor heart
Term
Describe Buerger's disease.
Definition
chronic inflammatory vascular occlusive disease of small arteries & also veins

occurs in young adults, largely males who smoke

begins distally & progresses proximally in both upper & lower extremities

patients exhibit paresthesias or pain, cyanotic cold extremity, diminished temperature sensation, fatigue, risk of ulceration & gangrene
Term
Describe Diabetic angiopathy.
Definition
inappropriate elevation of blood glucose levels - leads to accelerated atherosclerosis.
Term
Describe Raynaud's disease.
Definition
abnormal vasoconstrictor reflex exacerbated by exposure to cold or emotional stress - episodic spasm of small arteries & arterioles

tips of fingers dvelop pallor cyanosis, numbness & tingling - affects largely females - occlusive disease is usually not a factor
Term
Describe varicose veins.
Definition
distended, swollen superficial veins; tortuous in appearance; may lead to varicose ulcers
Term
Describe superficial vein thrombophlebitis.
Definition
clot formation & acute inflammation in a superficial vein - localized pain; usually in a saphenous vein.
Term
Describe chronic venous insufficiency.
Definition
pain: none to aching on dependency
pulses normal
color normal or cyanotic on dependency
venous valvular insufficiency: form fibroelastic degeneration of valve tissue to venous dilation
have muscle pump dysfunction
edema
Term
List the 3 stages of chronic venous insufficiency.
Definition
Grade I: mild aching, minimal edema, dilated superficial veins
Grade II: increased edema, multiple dilated veins, changes in skin pigmentation
Grade III: venous claudication, severe edema, cutaneous ulceration
Term
Differentiate between primary & secondary lymphadema.
Definition
primary: congenital condition with abnormal lymph node or lymph vessel formation

secondary: acquired, d/t injury of one or more parts of the lymphatic system
- can occur as a result of surgery, paralysis & disuse, or in tropical & subtropical areas, results from filariasis (nematode worm larvae in the lymphatic system.
Term
Define ETT.
Definition
exercise tolerance test.
Term
Define max ETT & submaximal ETT.
Definition

maximal ETT: defined by target endpoint heart rate age-adjusted = 220-age

use max HR with Karvonen's formula: Take 220-age = max HR

max HR - resting HR = target HR (HRR)

HRRx60% & HRRx80% = target training range

add HRR(60) & HRR(80) to resting HR to get target ranges during ex.

 

symptom limited: used to evaluate the early recover of patients after MI, coronary bypass, or coronary angioplasty Continuous: workload steadily progressed in 2-3 min. stages Discontinuous: allows rest in between stages; used for patients with more pronounced CAD

Term
During exercise, list the changes to the following: HR, systolic BP, diastolic BP, & RPP.
Definition
HR - increases linearly - plateaus just before VO2 max
systolic BP - increases
diastolic BP - stays the same or decreases
RPP - increases
Term
Define RPP.
Definition

rate pressure product = SBP x RHR

 

(RHR = resting heart rate)

Term
Angina is usually perceived at a given ____.
Definition
RPP.
Term
The ratings of perceived exertion scale was created by who?
Definition
Gunnar Borg
Term
The RPE is most useful with what populations?
Definition
when HR response is blunted by medications (ie medications) or a pacemaker.
Term
Describe the grading for the Borg Ratings of Perceived Exertion Scale.
Definition
6-20
descriptors like very, very light to somewhat hard (13) to very, very hard (19)
Term
List ECG changes with exercise in a healthy individual.
Definition
shortening of QT interval
ST segment depression, upsloping, less than 1 mm
exertional arrhythmias - rare, single PVC's
Term
List ECG changes in an individual with myocardial ischemia & CAD.
Definition
significant tachycardia
exertional arrhythmias - increased frequency
ST segment depression - horizontal or downsloping; greater than 1 mm below baseline indicative of myocardial ischemia
Term
Define MET.
Definition
amount of oxygen consumption at rest; equal to 3.5 mL/kg per minute
Term
MET levels can be directly determined during _____. How is this achieved?
Definition
during steady stage exercise, max VO2 achieved on ETT is divided by resting VO2
Term
Dynamic arm exercise results in a _____ VO2 max, ____ HR, _____ SV, & ____ systolic & diastolic BP.
Definition
lower, increased, lower, increased
Term
Describe exercise prescription for early cardiac rehab.
Definition
discontinous (interval training)
frequent rest periods
continuous training used later
low intensity
5-10 min. durations
warm up/cool down
Intensity usually 60-70% functional capacity - should be between 40-85% based on initial level of fitness
Term
If resistance exercises are used in cardiac rehab, what intensities are used, how is the patient monitored, and what should be avoided?
Definition
moderate (40% of MVC)
RPP monitoring
valsalva, breath-holding
Term
What cardiac patients should not perform resistance exercises?
Definition
poor left ventricular function, ischemic changes on ECG during ETT, functional capacity less than 6 METs, & uncontrolled hypertension or arrhythmias
Term
List how percentage of max HR is calculated when performing UE exercise vs LE exercise.
Definition
LE HR max = 220-age
UE HR max = 220-age-11
Term
70-85% HR max closely corresponds to ____.
Definition
60-80% functional capacity or VO2max
Term
RPE values of ____ correspond to 60% HR.
Definition
12-13
Term
RPE of ____ corresponds to 85% HR.
Definition
16 (hard)
Term
List 2 problems with the RPE scale.
Definition
Patients with psychological problems (depression) could affect ratings

Patients unfamiliar with the scale could affect selection of ratings
Term
List the best exercise prescription for severely compromised individuals.
Definition
multiple, short exercise sessions spaced throughout the day (3-10 minute sessions)
Term
List indications to modify exercise prescription.
Definition
HR is lower than target HR for a given intensity
RPE is lower for a given exercise
symptoms of ischemia
Term
As cardiac training progresses, ____ is increased first, then ____.
Definition
duration, intensity
Term
List exercise prescription for post-PTCA (percutaneous transluminal coronary angioplasty)
Definition
wait to exercise approx. 2 weeks post-PTCA to allow inflammatory processes to subside
Term
List the exercise prescription post CABG.
Definition
limit UE exercise while sternal incision is healing
avoid lifting, pulling, pushing for 4-6 weeks post-surgery
Term
Describe Phase I cardiac rehab.
Definition
During acute hospital stay
usually 3-5 days
-initiates early return to independence in ADL's
initial activities are low intensity (2-3 METs) progressing to 3-5 METs by D/C
RPE in light range; HR increase of 10-20 bpm above resting, depending on medications
short exercise sessions, 2-3x/day
Term
Post-surgical patients are typically progressed more ______ than post-MI.
Definition
rapidly
Term
Greater emphasis is placed on UE ROM with _____ patients.
Definition
post-surgical
Term
List some adverse response to inpatient exercise that would lead to exercise discontinuation.
Definition
Diastolic BP >110 mm Hg
Decrease in SBP >10 mm Hg
Significant ventricular or atrial dysrhythmias
second or third degree heart block
signs/symptoms of exercise intolerance, including angina, marked dyspnea, & ECG changes suggestive of ischemia
Term
List the end-goal of Phase I Cardiac rehab.
Definition
20-30 minutes of exercise, 1-2x/day at 4-6 weeks post MI
Term
Describe Phase 2 Cardiac Rehab.
Definition
outpatient cardiac rehab (subacute)
insurance usually approves for 3x/week for 12 weeks
progress towards full resumption of ADL's - habitual & occupational activites
3-4 sessions/week - 30-60 min. w/ 5-10 minutes of warm-up & cool down
pt's gradually weaned to spot checks & self-monitoring

Suggested end-point = 9 MET

begin with use of elastic bands & light weights (1-3 lbs) & progress to moderate loads, 12-15 comforable repetitions
Term
Is ESRD an indication or contraindication for inpt. & outpt. cardiac rehab?
Definition
indication
Term
Describe Phase 3 cardiac rehab.
Definition
Community exercise programs: post-acute, post-D/C from phase 2

promote self-regulation of exercise programs

location - community centers, YMCA, or clinical facilities

entry level criteria - functional capacity of 5 MET (safe resumption of most ADLs), clinically stable angina, medically controlled arrythmias

progression to 50-85% of functional capacity, 3-4x/wk, 45 min. or more per session

D/C typically in 6-12 mo.
Term
List patient criteria for resistance training with cardiac rehab.
Definition
Post-MI or cardiac surgery: minimum of 5 weeks

post-transcatheter prodecure: minimum of 3 weeks following procedure & 2 weeks of consistent participation in a supervised CR endurance training program
Term
With a resistance exercise program for cardiac rehab patients, the RPE scale should range from ____.
Definition
11-13 (light to somewhat hard)
Term
T/F.With a resistance exercise program in cardiac rehab, the RPP should not exceed that prescribed during endurance exercise.
Definition
true
Term
Describe the characteristics of CHF.
Definition
significant ventricular dysfunction, decreased CO, low functional capacity.
Term
Describe the four classes of CHF.
Definition
Class I: mild CHF: no functional limitations (can perform up to 6.5 mets)

Class II: mild limitations in function (up to 4.5 mets); comfortable at rest

Class III: marked CHF, marked limitation of physical activity (up to 3.0 METS), comfortable at rest - less than ordinary activity causes fatigue, palpitation, dyspnea, or anginal pain

Class IV: severe CHF - unable to carry out any physical activity (1.5 METs) - anginal pain present even at rest
Term
Describe exercise training for CHF patients.
Definition
use low intensities (40-60% functional capacity) - gradually increase durations, with frequent rest periods
RPE should be between 12-14
HR response may be impaired if patients are on digoxin

check for delayed responses of weight gain, edema lower extremities
NO resistance training with patients with capacities under 6.0 METS
Term
Describe characteristics and exercise prescription for patients with cardiac transplant.
Definition
pt's may have side-effects from immunosuppressive drug therapy: hyperlipidemia, hypertension, obesity, diabetes, leg cramps, decreased LE strength, increased fx risk secondary to prolonged corticosteroid use

HR alone inappropriate measure of exertion (heart is denervated) - use RPE, MET's dypsnea scale
Term
What should be avoided initially after implantation of pacemakers and defibrillators?
Definition
UE aerobic or strengthening exercises
Term
What can inadvertently cause a pacemaker or defibrillator to D/C?
Definition
electromagnetic devices (anti-theft devices)
Term
List the effects of physical training on SV, MVO2, respiratory capacity, functional capacity, glucose tolerance, & fibrinolytic activity.
Definition
SV: increased
MVO2: increased
respiratory capacity: improved
functional capacity: improved
glucose tolerance: improved
fibrinolytic activity: increased (increased coagulability)
Term
Describe the difference if you respond to a sudden collapse vs. unconscious victim.
Definition
sudden collapse: call 911 first
unconscious victim: give five cycles of CPR (2 minutes) first, then call 911
Term
LIst compression-ventilation ratio for adults, children, & infants.
Definition
30:2 for adults & children
15:2 for infants
Term
List the appropriate compression depth for adults, infant, & child.
Definition
adult = 1.5-2.0 inches
child = .5-1 inch
infant = .5 inch
Term
Blood typically clots within ____.
Definition
10 minutes
Term
List changes to RR, pulse rate, BP, & LOC with internal bleeding.
Definition
RR - increases
pulse rate - increases
BP - decreased
LOC - declines
Term
Define shock.
Definition
Failure of the circulatory system to perfuse vital organs
Term
Define Hemorrhagic shock.
Definition
severe internal or external bleeding
Term
Define psychogenic shock.
Definition
extreme stress - pulls blood to pool away from brain.
Term
Describe metabolic shock.
Definition
loss of body fluids from heat or severe vomiting/diarrhea
Term
Describe Cardiogenic shock.
Definition
MI or cardiac arrest results in pump failure
Term
Describe respiratory shock.
Definition
Respiratory illness or arrest results in insufficient oxygenation of blood
Term
Describe septic shock.
Definition
severe infections can cause blood vessels to dilate
Term
Describe neurogenic shock.
Definition
TBI/SCI/other neural trauma causes disruption of autonomic nervous system resulting in disruption of blood vessel dilation/constriction
Term
How soon should capillary refill return? What could be a possible cause of reduced capillary refill?
Definition
2 seconds; shock - blood being shunted away from periphery to vital organs to maintain core temp.
Term
Beta blockers for treatment of hypertension or cardiac disorders may _____ time to claudication or ____ symptoms.
Definition
decrease; worsen
Term
Pentoxifyline, dipyridamole, aspirin, & warfarin may ______ time to claudication.
Definition
improve
Term
Describe Modified Buerger-Allen exercises.
Definition
postural exercises plus active plantar & DF of ankle; active exercises improve blood flow during and after exercise; effects less pronounced in patients with PVD
Term
what strengthening exercise is most effective in increasing blood flow?
Definition
calf muscle strengthening
Term
List medications for arterial disease.
Definition
medications to decrease blood viscosity, prevent thrombus formation (heparin)
Vasodilators (controversial)
calcium channel blockers when vasospasm is involved.
Term
List treatments for CVI.
Definition
positioning: extremity elevation min. of 18 cm above heart - avoid dependent positioning

compression therapy - bandages applied withing 20 min. of rising

paste bandages (Unna boot) - Gauze impregnanted with zinc oxide, gelatin, & glycerine - applied for 4-7 days

graduated Jobst compression stockings, compression pump therapy, used for a 1-2 hours session 2x/daily
Term
DO NOT use compression therapy to a limb with an ABI ____ or evidence of _____.
Definition
<.8, active cellulitis, infection
Term
Lymphadema bandages have ____ resting pressure & _____ working pressure.
Definition
low, high
Term
emphasis of manual lymph drainage is to decongest _____ segments first, then _____, ______to ______.
Definition
proximal; extremities - distal to proximal
Term
WIth exercise prescription for lymphadema, what muscles should be worked & in what order?
Definition
work trunk & limb muscles first, then limb muscles from proximal to distal - performed with compression bandages on
Term
What exercises are contraindicated for patients with lymphadema?
Definition
strenous activities, jobbing, & ballistic movements - likely to exacerbate
Term
Compression garments are utilized at the end of _____ for lymphadema management.
Definition
Phase I
Term
What will high pressures do to a patient with lymphadema?
Definition
occlude superficial lymph capillaries & restrict fluid absorption
Term
Pressures higher than ____ are contraindicated as they can cause lymphatic collapse; contraindicated with soft tissue injury.
Definition
45 mm Hg
Term
Describe Phase I vs. Phase II management of lymphadema.
Definition
Phase I: management of edema secondary to lymphatic dysfunction

Phase II management: self-management
Term
During aquatic therapy, changes occur as a result of hydrostatic pressure & include a cephalad redistribution of blood flow. List changes to SV, CO, HR.
Definition
SV & CO increase
HR remains the same or slightly decreases
Term
How do diuretics work? Who shouldn't take diuretics?
Definition
inhibit tubular reabsorption of sodium & chloride in kidney, which inhibits water reabsorption & increases urine volume - decreased vascular resistance
elderly patients & patients with kidney failure should avoid thiazides - loop diuretics (furosemide, lasix are ok)
Term
List side effects of diuretics.
Definition
hyperglycemia, hypokalemia, hyperuricemia, increase in LDL levels, hypercalcemia
Term
List drug interactions with diuretics.
Definition
increases lithium absorption - can have lithium & digoxin toxicity
Term
What is a side effect of potassium-sparing diuretics that is different from all of the others?
Definition
can cause hyperkalemia rather than hypokalemia, especially if taking ACE inhibitors or potassium supplements
Term
Beta 1 receptors are located primarily in the _____ & Beta 2 receptors are in the _____.
Definition
heart, lungs
Term
What is the mechanism for beta blockers?
Definition
inhibit renin release from kidneys & decreases CO by lowering HR
Term
Who shouldn't take beta-blockers?
Definition
anyone with angina, COPD, & DM - should never discontinue use with a risk of sudden death from anginal attack
Term
What are side effects of beta blockers?
Definition
sleep disturbances, mental status changes, cold extremities
Term
What is the mechanism of calcium channel blockers? What are the side effects? What are possible drug interactions?
Definition
inhibit calcium ions - contractile process is inhibited, allowing vasodilation in coronary arteries & decreased peripheral resistance to blood flow

side effects: bradycardia, peripheral vasodilation - flushing, HA, ankle swelling, & reflex tachycardia

drug interactions: Verapamil can result in digoxin toxicity

Verapamil & beta blockers can cause cardiac depression & AV block
Term
What do alpha 1 & alpha 2 blockers do?
Definition
alpha 1 receptors are found in smooth muscle - inhibits smooth muscle allowing vasodilation in arteries & veins

alpha 2 blockers decrease SNS signals with decreased HR, peripheral resistance, & BP
Term
What are side effects of alpha 1 & alpha 2 blockers?
Definition
1 - syncope, headaches, & palpitations
2 -dry mouth, sedation, depression
Term
What are adverse effects of alpha 2 blockers?
Definition
with clonidine, risk of rebound hypertension on sudden withdrawal

with aldomet, decrease mental acuity & hemolytic anemia
Term
What are side effects of nitro?
Definition
dizziness, flushing and HA, reflex tachycardia
Term
What is the mechanism of ACE inhibitors? What are they used for?
Definition
inhibits conversion of angiotensin I to angiotensin II, which inhibits vascular smooth muscle contraction - also inhibits secretion of aldosterone by adrenal cortex - decreased sodium & water retention - get arterial vasodilation, decreased peripheral resistance, & increased blood flow

used as first step in L ventricular failure
Term
What are side effects & adverse effects of ACE inhibitors?
Definition
nonproductive dry cough, decreased taste perception

adverse effects - hypotension, hyperkalemia, angioedema
Term
What are the four steps to treating CHF?
Definition
step 1 - ACE inhibitors
2 - loop diuretics
3 - nonselective beta blockers & selective alpha 1 andrenergic blocker
4 - Digoxin
Term
List side effects of digoxin & signs of digoxin toxicity.
Definition

side effects: fatigue, HA, muscle weakness, bradycardia, arrythmias, V-fib

toxicity: any cardiac arrythmia, anorexia, nausea, vomiting, mental status change, hallucinations, blurred vision

Term
What are side effects of vasodilators?
Definition
GI disturbances, HA, flushing, nasal congestion
Term
What is Ticlopidine (Ticlid)? What are adverse effects?
Definition
same mechanism as aspirin - prevents TIA & stroke

side effects: GI symptoms, dizziness, neutropenia which can lead to agranulocytosis
- inhibits enzymes that break down dilantin & theophylline (bronchodilator) - can increase levels of both
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