Term
| Prenatal growth is most likely dependent on what factor for growth? |
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Definition
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Term
| During neontal period how fast is growth? |
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Definition
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Term
| Define neonate, infant, childhood in terms of years. |
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Definition
neonate birth-1y/o
infant 1-3y/o
childhood 3-puberty |
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Term
| WHat is the rate of growth during infancy? |
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Definition
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Term
| What is the rate of growth during childhood? |
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Definition
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Term
| What age does the growth spurt occur for males and females on average? |
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Definition
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Term
| What age period does linear growth begin to stablize? |
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Definition
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Term
| No sign of puberty by what age in males and females is a red flag for growth delay? |
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Definition
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Term
| What age period do the epiphyseal growth plates close? |
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Definition
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Term
| What is the definition of short stature? |
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Definition
| less than 2.0 standard deviations for age |
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Term
| Why might one want to evaluate tissue transglutaminase antibody with IgA in a patient with growth delay? |
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Definition
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Term
| How is bone age measured? |
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Definition
| left hand x-ray compared to known ages |
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Term
| If Bone age<actual age, what does this imply? |
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Definition
| there is still potential to grow |
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Term
| At what bone age, do males and females stop growing? |
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Definition
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Term
| What is the difference between genetic short stature and constitutional delay? |
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Definition
| with constintutional delay there is a delay in the growth spurt. |
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Term
| With congenital growth hormone deficiency, how does growth in the child progress? |
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Definition
| vertical growth stays constant while they may continue to gain weight |
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Term
| What other defects are present with congenital growth hormone deficiency? |
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Definition
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Term
| In acquired growth hormone deficiency, what is true of IGF-1? |
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Definition
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Term
| What level of GH defines growth hormone deficiency? |
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Definition
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Term
| What four options do you have in testing using the growth hormone provocative test? |
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Definition
| L-dopa, clonidine, insulin, arginine |
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Term
| What are the four negatives of the growth provocative test? |
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Definition
high level of varience
60% of short stature patients with negative test would actually benefit from treatment
stress involved with the actual testing could give false levels
those with delayed growth spurts may give false + |
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Term
| What are five signs of Turner's Syndrome? |
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Definition
short stature
wide caring angles
edema
webbed neck
sheilded chest |
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Term
| What three physiological effects does hypercortisolism have on endocrine systems? |
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Definition
| decreases GH, increase somatostatin, causes IGF-1 to not interact properly |
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Term
| Give up to 9 side effects for human growth hormone? |
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Definition
diabetes
pseudotumor cerebri (headache)
allergy
arthritis
carpal tunnel
slipped capital femoral epiphyseal
scoliosis
breast/prostate cancer
colon polyps
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