generic: atomoxetine

class: drugs for ADHD

indication: ADHD in children over 6

dose: one or two doses, max 1.4mg/kg or 100mg

SIDE EFFECTS

common: nausea, vomitting, abdominal pain, dyspepsia, decreased appetite, dry mouth, increased BP, dizziness, somnolance, irritability, temper tantrums,

infrequent: palpitations, tachycardia

rare: suicidal thoughts and actions.

generic: duloxetine

class: SNRI

indication: depression

dose: 30 - 60mg once or twice a day

SIDE EFFECTS

common: suicidality, acute mania, hypomania, hepatotoxic, mydriasis, orthostatic hypotension, elevated BP, palpitations, GI upset, chills, musculoskeletal pain, anxiety, sleep disturbances, sexual dysfunction

infrequent

rare:

dose: twice daily SC injections

generic: moxonidine

class: centrally active hypertensive

indication: hypertension

dose: 200mcg mane initially, up to 600mcg daily in 2 divided doses

SIDE EFFECTS

common: somnolence, weakness, dizziness, dry mouth, rash, bradycardia

generic: paliperidone

class: atypical antipsychotic

indication: schizophrenia

dose: 3 - 12mg once daily

SIDE EFFECTS

common: headache, akasthesia, EPSE, nausea, tachycardia, weight gain, orthostatic hypotension, hyperprolactinaemia, somnolence

infrequent: ECG changes

generic: vareniclene

class: antismoking

indication: smoking cessation

dose: 0.5mg d to 1mg bd

SIDE EFFECTS

common:

nausea, vomitting, dyspepsia, flatulance, increased appetite, altered taste, headache, dizziness, insomnia, abnormal dreams, insomnia

infrequent:

AF, palpitations, dry mouth, musculoskeletal pain, gastritis, GORD, abdominal pain, raised liver enzymes, somnolence, tremor, rash, mood changes, glycosuria, polyuria, weight increase

Generic: rotigotine

Class: non-ergot dopamine agonist

Indication: parkinson's disease

Dose: once daily patch (2 - 4 mg /24 hours)

SIDE EFFECTS

common: nausea, application site irritation, dizziness, headache, somnolence, insomnia, vomitting, fever, compulsive behaviour

infrequent: tachycardia, elevated blood pressure, orthostatic hypotension, hallucinations, retinal degradation, cardiac valvopathy, dyskinesia, melanoma, peripheral oedema,

generic: sitagliptin

class: dipeptidyl peptidase 4 inhibitor

indication: type 2 diabetes

dose: once daily dosing

SIDE EFFECTS

nasopharyngitis, headache, nausea, UTI, hypoglycaemia, allergy

Thelin

generic: Sitaxentan

class: endothelin antagonist

indication: pulmorary hypertension

dose:

SIDE EFFECTS

common: headache, peripheral oedema, nasal congestion, GI upset, fatigue, muscle cramp, insomnia, epistaxis, flushing

infrequent

rare:

generic: telbivudine

class: enantiomer of thymidine

indication: chronic hep B

dose: 600mg daily

SIDE EFFECTS

common: myopathy, pulmonary neuropathy, GI upset, fatigue, malaise, pyrexia, headache, cough, pain

generic: strontium ranelate

class: antiresorptive

indication: osteoporosis

dose: 2 g daily

SIDE EFFECTS

common:

nausea, diarrhoea, headache, dermatitis, increased creatinine kinase concentration

rare: DVT, pulmonary embolism, CNS disturbances ie memory loss, seizures, disturbed consciousness

generic: ziprasidone

class: atypical antipsychotic

indication: acute mania, schizophrenia

dose: 20 - 80mg bd

SIDE EFFECTS

common: hypersalivation, weakness, EPSE, sedation, anxiety, agitation, orthostatic hypotension, tachycardia, blurred vision, mydriasis, nausea, constipation, dry mouth, urinary retention, sexual adverse effects, weight gain, hyperprolactinaemia

infrequent

SIADH, hypo/hyper thermia, allergic reactions, ECG changes, anaemia, seizures

rare:

Lyrica

generic: pregabalin

class:

indication: partial seizures, neuropathic pain

dose: 75 - 300mg bd

SIDE EFFECTS

common: dizziness, drowsiness, visual disturbances, ataxia, dysarthria, lethargy, euphoria, tremor, weight gain, constipation, dry mouth, memory impairment, peripheral oedema, facial and tongue oedema

infrequent

depression, confusion, agitation, hallucinations, excessive salivation, urinary incontinence, myalgia, tachycardia, heart failure,

rare: