Term
| what is the structure of a monoamine? |
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Definition
| amine group connected to aromatic ring by a 2 carbon chain |
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Term
| Function of glutamic acid decarboxylase (GAD) |
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Definition
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Term
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Definition
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Term
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Definition
Muscarinic
Fast IPSP and slow EPSP |
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Term
| Glutamate pyramidal cells of the cerebral cortex |
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Definition
| Basal ganglia, thalamus, spinal cord |
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Term
| GABA in cerebellar cortex (purkinje cells) |
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Definition
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Term
| GABA in caudate nucleus and putamen |
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Definition
| globus pallidus and substantia nigra |
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Term
| GABA in globus pallidus and substantia nigra |
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Definition
| thalamus, and subthalmic nuclei |
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Term
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Definition
NT and voltage gated
free Mg2+ blocks channel allowing Ca flux |
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Term
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Definition
ligand gated
benzo and barbs attach here |
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Term
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Definition
G protein
EtOH and baclofen |
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Term
| mech of action of tetanus and strychnine |
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Definition
| inhibit presynaptic GABA release |
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Term
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Definition
| Ab's to GAD causing autoimmunity |
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Term
| Benzo treatment of seizure |
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Definition
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Term
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Definition
| inhibit enzymes that deactivate GABA |
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Term
| Topiramate mech of action on GABA |
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Definition
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Term
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Definition
| pars compacta and ventral tegmental |
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Term
| nigrostriatal tract of dopa |
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Definition
| smooth muscle action (D2 receptor) |
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Term
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Definition
fear and reward response
D1 in nucleus accubmens |
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Term
| mesocortical tract of dopa |
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Definition
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Term
| tubero-infundibular tract |
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Definition
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Term
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Definition
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Term
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Definition
raphe nucleus
1and2 receptor- mood, appetite, energy, sexual function
3- nausea |
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Term
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Definition
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Term
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Definition
Parkinsons- locus ceruleus degeneration
cocaine- inhibits reuptake
panic attacks- reuptake deficiency |
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Term
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Definition
| nucleus basalis of Mynert(neocortex)/pedunculopontine nucleus(projects to thalamus) |
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Term
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Definition
Peripheral: PS stimul
CNS: inhib or excit |
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Term
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Definition
Nicotinic- SLUDGE
Muscarinic- Hot as a hare |
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