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Neuroscience chapter 2
Mapping the Human Brain
124
Psychology
Undergraduate 4
10/16/2010

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Term
Neurons
Definition
The basic unit of the nervous system, each composed of a cell body, receptive extensions, and a transmitting extension
100-150 billion
Term
Neuron doctrine
Definition
1) the brain is composed of separate neurons and other cells that are independent structurally, metabollically, and functionally; and 2) information is transmitted from cell to cell across tiny gaps.
Term
synapses
Definition
the gaps which information is transmitted
10^15 synapses
Term
Glial cells
Definition
Nonneuronal brain cells that provide structural, nutritional, and other types of support to the brain.
Term
Mitochondrion
Definition
Cellular organelle that provides energy for the cell's processes
Term
cell nucleus (soma)
Definition
The spherical central structure of a cell that contains the chromosomes
Term
Ribosomes
Definition
Structures in the cell body where genetic info is translated to produce proteins
Term
Four Functional zones
Definition
Input zone
integration zone
conduction zone
output zone
Term
Input zone
Definition
cellular extensions called dendrites serve as the input zone, receieving information from other neurons.
Term
Integration zone
Definition
A cell body region, which contains the nucleus. Inputs are combined and transformed in the cell body
Term
Conduction zone
Definition
the axon, leads way from the cell body, transmitting the electrical impulse away
Term
Output zone
Definition
Specialized swellings at the ends of the axon, the axon terminals. They communicate the cells activity to other cells at the synapse.

axons can vary GREATLY in size
Term
Neurons can be classified by
Definition
Shape, size, or function
Term
Multipolar neurons
Definition
have many dendrites and a single axon, and they are the MOST COMMON type of neurons
Term
Bipolar neurons
Definition
have a single dendrite at one end of the cell and a single axon at the other end. This neuron is common in sensory systems (e.g. vision)
Term
Unipolar neurons
Definition
Have a single extension, usually thoguht of as an axon, that branches in two directions ater leaving the body. One end is the input zone that branches with dendrites, the other the output zone (e.g. touch)
Term
Motoneurons
Definition
when the axon terminals contact muscles or glands, providing a pathway for the brain and spinal cord to control body movements and organ function
Term
Sensory neurons
Definition
neurons directly affected by environmental stimuli; they respond to light, odor, or touch.
Term
Interneurons
Definition
constitute the vast majority. receive input from and send their output to other neurons.
Term
glial cells affect neuronal functioning by
Definition
providing raw materials and chemical signals that alter structure
Term
Astrocyte
Definition
a star shaped cell with numerous processes extending in all directions wearving among neurons. recieve synapses directly from neurons and monitor activity of nearby neuronal synapses.
Term
Microglial cell
Definition
very small and remarkably active, continually extending and withdrawing very fine processes that repair and clean damaged cells. "Brains cleanup crew"
Term
Myelin
Definition
fatty insulating substance, giving the appearance of a string of slender beads
Term
Myelination
Definition
the process of ensheathing axons.
Term
Node of ranvier
Definition
between each pair of myelinated segments is a small gap where the membrane is exposed.
greatly increase the speed at which axons send information.
Term
Multiple sclerosis
Definition
a disease that interferes with the myelin sheath, causing individuals great pain.
Term
Oligodendrocyte
Definition
much smaller than astrocyte with fewer extensions. contribute sheathing to numerous adjacent axons, more commonly associated with cell bodies. (brain and spinal cord)
Term
Schwann cell
Definition
for axons outside the brain and spinal cord, myelin is provided by this. a single ensheathes a limited length of a single axon
Term
edema
Definition
swelling of the glial cells
Term
Arborization
Definition
elaborate branching of the dendrites of some neurons
Term
Presynaptic neurons
Definition
release of the neurotransmitter
Term
postsynaptic neurons
Definition
receive of the neurotransmitter
Term
3 components of the synapse
Definition
presynaptic membrane
postsynaptic membrane
synaptic cleft
Term
Presynaptic membrane
Definition
the axon terminal of the presynaptic neuron
Term
postsynaptic membrane
Definition
on the surface of the dendrite or cell body of the postsynaptic neuron
Term
synaptic cleft
Definition
the gap that seperates the presynaptic and postsynaptic membranes.
Term
Synaptic vesicles
Definition
small spheres which are used to communicate with postsynaptic neurons
Term
receptors
Definition
specialized protein molecules that capture and react to molecules of the neurotransmitter
Term
neural plasticity
Definition
the ability of the nervous system to change in response to the experience or environment.
Term
Axon hillock
Definition
a cone-shaped projection of the cell body. The axon hillock is the integration zone, gathering information from all the synapses on the neuron's dendrites and soma, triggering electrical impulse to carry a message toward its targets.
Term
axon collaterals
Definition
the axons division into several branches allowing the neuron to influence many cells
Term
innervate
Definition
provide neural input
Term
axonal transport
Definition
the movement of materials within the axon
Term
gross neuroanatomy
Definition
anatomical features of the nervous system that are apparent to the naked eye.
Term
Nerves
Definition
collection of axons bundled together, that extend throughout the body
Term
Cranial nerves
Definition
connected directly to the brain
serve the sensory and motor systems of the head and neck. 12 of them
Term
spinal nerves
Definition
connected at regular intervals to the spinal chord
31 pairs
Term
each nerve consists of the fusion of two distinct branches called
Definition
dorsal root, ventral root
Term
dorsal root
Definition
consists of sensory projections from the body to the spinal cord
Term
ventral root
Definition
consists of motor projections from the spinal cord to the muscles
Term
Autonomic nervous system
Definition
regulator system that primarily controls the viscera
Term
preganglionic neurons
Definition
innervate the ganglia
Term
postganglionic neurons
Definition
innervate the body
Term
sympathetic nervous system
Definition
found exclusively in the spinal cord. cells send their axons a short distance to innervate the sympathetic chains, consists of autonomic ganglia running along each side of the spinal column.
Term
parasypathetic nervous system
Definition
preganglionic neurons are found above and below those of the sympathetic system. positioned near the organ affected
Term
enteric nervous system
Definition
a local network of sensory and motor neurons that regulates function of the guy, under the control of the CNS.
Term
Cerebral hemispheres
Definition
right and left halves of the forebrain
Term
Gyrus
Definition
ridged or raised portion of a convoluted brain surgace
seperated by SULCUS
Term
four regions of the brain
Definition
front lobe
parietal lobe
temporal lobe
occipital lobe
Term
sylvian fissure
Definition
deep fissure that dermarcates the temporal lobe
Term
central sulcus
Definition
fissure that divides the front lobe from the parietal lobe
Term
cerebral cortex
Definition
outerlayer of cerebrum, consists of nerve cell bodies and their branches.
"seat of complex cognition"
Term
postcentral gyrus
Definition
mediates sense of touch. behind the central sulcus.
Term
precentral gyrus.
Definition
crucial for motor control. in front of the central sulcus
Term
Corpus callosum
Definition
crosses the midline and allows communication between the left and right hemispheres
Term
different types of matter in the brain (2)
Definition
white matter
gray matter
Term
white matter
Definition
beneath the outersurface and consists of mostly fiber tracts.

insulates the axons of many neurons
Term
gray matter
Definition
darker color and dominated more by nerve cell bodies and dendrites, devoid of myelin.
Term
neural tube
Definition
made of cells, and the interior is filled with fluid
Term
forebrain
Definition
contains cerebral hemispheres, thalamus, and hypothalamus.

very front is the telencephalon
Term
diencephalon
Definition
includes thalamus and hypothalamus
Term
hindbrain
Definition
contains the cerebellum, pons, and medulla
Term
Metecephalon
Definition
develops into the cerebellum and the pons
Term
myelencephalon
Definition
more commonly called the medulla
Term
brainstem
Definition
usually refers to the midbrain, pons, and medulla combined.
Term
within each region of the brain are neurons called ______ and axons called _______.
Definition
nuclei ; tracts.
Term
basal ganglia
Definition
includes the caudate nucleus, the putamen and the globus pallidus in the telencephalon, and the substantia nigra in the midbrain
Term
limbic system
Definition
a loosely defined widespread network of structures involved in emotion and learning
Term
amygdala
Definition
consists of several subdivisions with diverse functions
emotional regulation, perception of odor
Term
hippocampus
Definition
temporal lobe important for learning and memory
Term
fornix
Definition
fiber tract that extends from hippocampus (important for learning)
Term
cingulate gyrus
Definition
portion of the limbic system found in the frontal and parietal (directing attention).
Term
olfactory bulb
Definition
sense of smell
Term
mammillary bodies
Definition
a pair of nuclei at the base of the brain
Term
thalamus
Definition
uppermost portion of the diencephalon. way stations to the cerebral cortex. sensory information enters the thalamus
Term
hypothalamus
Definition
small, packed with many distinct nuclei that have vital functions. implicated in hunger, thirst, temperature regulation, reproductive behaviors, and more. controls pituitary and hormone secretion.
Term
Two pairs of bumps in the midbrain
Definition
superior colliculi, inferior colliculi
Term
superior colliculi
Definition
recieve visual information and involved in direction of gaze and visual attention
Term
inferior colliculi
Definition
recieve auditory information
Term
tectum
Definition
the portion containing the superior and inferior colliculi
Term
red nucleus
Definition
communicates with motoneurons in the spinal cord.
(reddish tint)
Term
reticular formation
Definition
distributed network of neurons involved in arousal (walking)
Term
the cerrebellum is important for:
Definition
motor coordination and control and some aspects of cognition, including learning.
Term
the medulla maintains:
Definition
vital body functions
Term
pyramidal cell
Definition
most prominent kind of neuron in the cerebral cortex. pyramid shaped cell body
Term
apical dendrite
Definition
one dendrite of the cell the extends to the outermost surface of the cortex
Term
basal dendrite
Definition
spread out horizontally from the cell body
Term
cortical columns
Definition
one of the vertical columns that constitute the basic organization of the neocortex
Term
Meninges
Definition
protective sheets of tissue around the brain
Term
dura mater
Definition
the tough outermost sheet
Term
pia mater
Definition
delicate, innermost layer, adheres tightly to the surface of the brain
Term
arachnoid
Definition
WEBLIKE membrane between the dura mater and the pia mater
Term
cerebrospinal fluid (CSF)
Definition
fluid that fills the space within the arachnoid
Term
meningitis
Definition
inflammation of the meninges usually caused by viral infection
Term
ventricular system
Definition
series of chambers inside the brain filled with CSF (cerebral spinal fluid
Term
CSF functions
Definition
shock absorber for the brain, protecting it from sudden movements that would crush it against the skulls
2) medium to exchange materials
Term
Lateral ventrical
Definition
connects 4 hemispheres of the brain
Term
choroid plexus
Definition
membrane which produces csf filtering blood
Term
third ventricle
Definition
midline ventricle that conducts cerebrospinal fluid from the lateral ventricles to the 4th ventricle
Term
fourth ventricle
Definition
passageway with the pons that recieves fluid from the third and releases it to surround the brain
Term
Carotid arteries
Definition
major arteries that ascend the left and right sides of neck to the brain, supplies blood to anterior and middle cerebral arteries
Term
posterior cerebral arteries
Definition
blood supply for the rest of the cortex
Term
basilar artery
Definition
artery formed by the fusion of the vertebral arteries, supplies blood to the brainstem and posterior cerebral arteries
Term
circle of willis
Definition
structure at the base of the brain formed by the joining of the carotid and basilar arteries

allows for alternate route for blood if any arteries are damaged or blocked
Term
stroke
Definition
no blood flow to region of brain caused by blockage
Term
bloodbrain barrier
Definition
make the movement of substances from blood vessels to brain more difficult, giving the brain more protection from substances found in blood
Term
Angiography
Definition
brain imaging technique which specialize x-ray image of the head is taken after the cerebral blood vessels have been filled with radiopaque dye
Term
computerized axial tomography (CAT)
Definition
noninvasive technique for examining brian structure through computer analysis of x-ray absorbtion

mathematical models used to map the brain.
Term
Magnetic resonance imaging (MRI)
Definition
uses magnetic energy to generate images that reveal some structural details in the living brain

high resolution image
Term
positron emission tomography (PET)
Definition
combining tomography with injections of radioactive substances used by the brain

trying to see activity more than structure.
Term
Functional MRI (fMRI)
Definition
MRI that detects changes in blood flow and therefore identifies regions of the brain that are particularly active during a given task

good speed, excellent sharpness
great for cognitive science
Term
optical imaging
Definition
method for visualizing brain activity in which near-infrared light is passed through the scalp and skull.
Term
transcranial magnetic stimulation (TMS)
Definition
localized, noninvasive stimulation of cortical neurons through the application of strong magnetic fields
Term
Magnetoencephalography (MEG)
Definition
a large array of SQUIDS used to create realtime maps of brain activity from localized cortical magnetic fields

responds very quickly to moment-by-moment changes
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