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Neurophysiology
Tests over basic Neurophysiology #1
9
Physiology
Undergraduate 3
10/11/2007

Additional Physiology Flashcards

 


 

Cards

Term
Describe the origin of biological amines
Definition
Synthesized from Amino Acids
Term
List 3 catecholamine biogenic amines, and give examples/locations of each of their respective neurons that release catecholamines
Definition

1. Dopamine: Midbrain neurons (including substantia nigra)

 

2. Epinephrine: "Adrenaline"; released by adrenal medulla (not a common neurotransmitter)

 

3. Norepinephrine: "Noradrenaline"; released by sympathetic postganglionic neurons and some CNS neurons. 

Term
How is the actions of catecholamines terminated?
Definition
stopped by (1) uptake, and (2) enzyme degredation (MAO)
Term
What types of drugs act on Dopaminergic synapses?
Definition
Psychoactive drugs: amphetamines, cocaine, LSD
Term
How is serotonin synthesized? How is it's action terminated?
Definition

Synthesized from tryptophan

 

Stopped by re-uptake and MAO (enzyme) 

Term

What mood-altering drugs act on Serotonin?

 

 Why is serotonin important?

 

Where is serotonin found? 

Definition

mood-altering drugs (diazapam; LSD; antidepressants)

 

Important in pathways that control mood

 

NT of many brainstem neurons which project to many areas of the CNS. 

Term

Where is histamine found?

 

What is it's function? 

Definition

Released by some neurons in the hypothalamus

 

Important nt in regulation of sleep and wakefulness

  

Term

What are the excitatory amino acid nt's?

 

What are their effects when binding to their receptors? (channels involved) 

Definition

glutamate and aspartate

 

bind to NMDA receptors:  Contain channels permeable to  to Na+, K+ and Ca2+; Repeated activation is linked to Long Term Potentiation (LTP)

 

- Can cause Excitotoxicity 

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