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Neurology Primary Brain Tumors
Primary Brain Tumors
20
Aerospace Engineering
Kindergarten
05/16/2012

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Cards

Term
Most common adult brain tumor. Grave prognosis (<1 year life expectancy)
Stain astrocytes
Definition
Glioblastoma multiforme

Found in the cerebral hemispheres
Term
Can cross corpus callosum ("butterfly glioma")
stains astrocytes

Stain astrocytes for GFAP.

"Pseudopalisading" pleomorphic tumor cells - borders central area of necrosis and hemorrhage
Definition
Glioblastoma multiforme
Term
2nd most common adult brain tumor.

Arises from arachnoid cells external to brain
Definition
Meningioma

Usually resectable. Located in convexities of hemispheres and parasagittal region
Term
Spindle cells concentrically arranged in a whorled pattern.
Showing psammoma bodies (laminated calcifications)
Definition
Meningiomas

Arise from arachnoid cells external to brain
Term
3rd most common adult tumor. Usually found at the cerebopontine angle. S-100 positive
Definition
Schwannoma
Term
Localized to CN VIII and commonly found bilaterally in neurofibromatosis type 2
Definition
Schwannoma (acoustic schwannoma)
Term
Rare, slow growing frontal lobe tumor. Shows chicken-wire capillary pattern
Definition
Oligodendroglioma
Term
Histology of tumor cells look like "fried egg", rounded nuclei with clear cytoplasm (peri-nuclear halo and cytoplasmic clearing)
Definition
Oligodendroglioma
Term
Causes bitemporal hemianopia and hyper/hypo pituitarism
Definition
Pituitary adenoma

Located in rathke's pouch
Term
In children; mostly found in the posterior fossa. May be supratentorial.
Definition
Pilocytic astrocytoma

Usually has a good process and is benign
Term
Highly malignant cerebellar tumor. A form of primitive neuroectodermal tumor (PNET) that can compress the 4th ventricle
Definition
Medulloblastoma
Term
Appears as Homer Wright Rosettes. Solid blue cells on histology surrounding intracranial tangles
Definition
Medulloblastoma
Term
Displays rosenthal fibers - eosinophilic corkscrew fibers
Definition
Pilocystic Astrocytoma
Term
Commonly found within the 4th ventricle. Can cause hydrocephalus.
Definition
Ependymoma

Poor prognosis
Term
Appears with perivascular pseurosettes surrounding cerebral vessel. Rod shaped blepharoplasts near nucleus
Definition
Ependymoma
Term
Most often cerebellar, associated with Von Hippel-Lindau syndrome
Definition
Hemangioblastoma
Term
Foamy cells and high vascularity
Can produce erythropoietin to cause secondary polycythemia
Definition
Hemangioblastoma
Term
Benign childhood tumor. Can also cause bilateral hemi-anopia
Definition
Craniopharyngioma
Term
Derived from Rathke's pouch, most common childhood supratentorial tumor
Definition
Craniopharyngioma
Term
Shows rosenthal fibers- eosinophilic corkscrew fibers
May be cystic and solid at the same time
Definition
Pilocytic astrocytoma
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