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Neurology Part 2 pathophysiology
Part 2 neurology pathophysiology
114
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Professional
05/13/2012

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Term
The meatus of the ear appears above the __________?
Definition
mastoid process
Term
________________ promote conductivity of sound between the external ear and middle ear.
Definition
mastoid air cells
Term
Symptoms of ear pain, fever, irritability, an inflamed tympanic membrane and fluid in the middle ear are signs of?
Definition
acute otitis media
Term
nonsuppurative and suppurative are classifications of?
Definition
acute otitis
Term
Impaired judgement and decision making?
Definition
confusion
Term
beginning loss of consciousness?
Definition
disorientation
Term
limited spontaneous movement or speech, exhibits slow vocalization, decreased motor skills and oculomotor activity?
Definition
lethargy
Term
mild to moderate reduction in arousal, continuous stimulation is needed for arousal and the eyes are usually closed?
Definition
obtundation
Term
deep sleep or unresponsiveness, vocalization only in response to painful stimuli?
Definition
stupor
Term
Displays no vocalizatoin, no spontaneous eye movement, and no arousale to any stimulus, BUT brain stem reflexes are intact?
Definition
Coma
Term
Eye opening, best verbal response and best motor response are parts of the standardized ____________ to determine the severity of the patient's brain injury?
Definition
Glasgow Coma Scale
Term
Compression of the brain stem can be caused by?
Definition
hematoma, hemorrhage, aneurysm, cerebellar hemorrhage, infarcts, abscesses, neoplasms and demyelinating disorders
Term
Extracerebral disorders include?
Definition
neoplasms, closed-head trauma with subsequent bleeding and subdural accumulation of pus
Term
Sudden abnormal electrical activity in the brain is __________
Definition
seizure
Term
Rapid and uncontrollable shaking of he body?
Definition
convulsion
Term
repeated seizures occuring over time?
Definition
epilepsy
Term
Occurrence of 2nd, 3rd or multiple seizures before regaining consciousness from the preceding seizure?
Definition
status epilepticus
Term
Generalized tonic clonic movement is AKA
Definition
grand mal seizure
Term
absence AKA
Definition
petit mal seizure
Term
Generalized tonic-clonic movement and absence involve ___________ areas
Definition
bilateral
Term
focal motor and psychomotor seizures involve __________ area?
Definition
unilateral
Term
cerebral dysfunction secondary to drug intoxication or nervous system disease as classified as?
Definition
acute confusional states
Term
Loss of more than one cognitive or intellectual function is ?
Definition
dementia
Term
Severe cognitive dysfunction in older people which is chronic and is an irreversible dementia?
Definition
Alzheimer disease
Term
Alteration in cerebral hemodynamics due to increase of extracellular or intracelluarl fluid within the brain after brain insult from trauma, infection, hemorrhage, tumor, ischemia, infarct or hypoxemia?
Definition
cerebral edema
Term
Flaccidity is a type of ?
Definition
hypotonia
Term
Spasticity and rigidity are types of?
Definition
hypertonia
Term
Spasticity and rigidity are types of?
Definition
hypertonia
Term
paresis and paralysis are types of?
Definition
hypokinesia
Term
Blunt brain trauma is AKA
Definition
closed
Term
Open brain trauma is AKA
Definition
penetrating
Term
Most common type of brain injury?
Definition
concussions
Term
force of impact on the brain typically produces _______ on the brain?
Definition
contusions (bruises)
Term
Immediate loss of consciousness, loss of reflexes transient stop of respirations, brief bradycardia and drop in blood pressure are manifestions of?
Definition
a contusion
Term
Extradural hematomas, epidural hematomas or epidural hemorrhages most often have a/an _________ as the source of bleeding?
Definition
artery
Term
Tearing of the bridging veins occurring either rapidly and or subacutely are indicative of ?
Definition
subdural hematoma
Term
When small blood vessels are traumatized by shearing forces?
Definition
intracerebral hemaotma
Term
Structural defect involving the lamina (neural arch of the vertebra)?
Definition
spondylolysis
Term
When vertebra slide forward in relation to inferior vertebra, common at L5-S1?
Definition
spondylolisthesis
Term
Entrapment of single nerve root in the lateral recess or diffuse central stenosis involving many roots may represent?
Definition
spinal stenosis
Term
Ischemic (thrombotic or embolic), global hypoperfusion (as in shock) or hemorrhagic are types of?
Definition
CVA(s)
Term
HTN, smoking, elevated blood lipoprotein-a, DM, insulin resistance, impaired cardiac function, non-rheumatic afib, coag disorders, polycythemia, thrombocythemia, postmenopausal estrogen use are risk factors for?
Definition
CVA
Term
TIA, strokes-in-evolution, completed strokes are ____________
Definition
thrombotic strokes
Term
strokes or infarcts that involve small arteries and occur frequently in the basal ganglia, internal capsules and brain stem are _____________
Definition
lacunar
Term
AVM, cavernous angioma, capillary telangestasis, venous angioma are types of _________
Definition
vascular malformations
Term
A tangled mass of dilated blood vessels is known as ___________
Definition
AVM
Term
_____________ headaches are seen mostly in men age 20-50, several attacks during the day followed period of spontaneous remission?
Definition
cluster
Term
Most common type of heaache, occurs in 40-60% population, is bilateral, mild to moderate in severity, sensation of tight band or pressure around head, comes in episodes - may last hours or several days?
Definition
tension
Term
primary or metastatic are classification of _________ tumors?
Definition
cranial
Term
Astrocytoma, glioblastoma multiforme, oligodendrogliomas, ependyoma adn meningiomas are classifications of _______?
Definition
common primary brain tumors
Term
Bacterial meningitis affects the _____________?
Definition
pia mater, arachnoid and subarachnoid space, CSF and ventricles
Term
aseptic meningitis affects ______?
Definition
meninges
Term
encephalitis affects _________?
Definition
meninges, white and gray matter
Term
Infectious agents of bacterial meningitis are _________?
Definition
Neisseria, pneumococci, haemophilus
Term
Infectious agents of aseptic meningitis are ?
Definition
enteroviral viruses and herpes simplex I
Term
Infectious agents of encephalitis are?
Definition
arthropod-borne viruses, herpes simplex I, complications of systemic viral infection
Term
With this infection meningeal vessels become hyperemic and permable?
Definition
bacterial meningitis
Term
With this infection there is nerve cell degeneration?
Definition
encephalitis
Term
This infection is similar to a bacterial infection?
Definition
aseptic meningitis
Term
bacterial meningitis manifestations?
Definition
throbbing headache, flexion of legs and thighs, neck stiffness, projectile vomiting and confusion
Term
aseptic meningitis manifestations?
Definition
mild symptoms as compared to bacterial meningitis, but similar
Term
encephalitis manifestations?
Definition
fever, delirium, confusion, coma, seizure, cranial nerve palsies, paresis and paralysis
Term
viral, nonpurulent or lymphocytic meningitis are also known as?
Definition
aseptic meningitis
Term
Progressive cognitive dysfunction in conjunction with motor and behavioral alterations in an HIV patient is?
Definition
HIV encephalopathy
Term
Multinucleated giant cell encephalitis involving diffuse degeneration of the spinal cord in an HIV patient - manifesting as a progressive spastic paraparesis with ataxia, leg weakness, upper motor neuron signs, incontinence, and posterior column sensory loss is diagnosed as?
Definition
vascular myelopathy
Term
HIV patient with painful dysthesias and paresthesias in the extremities, weakness, and decreased or absent distal reflexes is diagnosed as?
Definition
peripheral neuropathy
Term
HIV patients may develop this diagnosis at the time of positive seroconversion manifesting as headache, fever, meningismus with cranial nerve involvement especially of V and VII?
Definition
aseptic meningitis
Term
Papovavirus, demyelinating disorders, progressive multifocal leukoencephalopathy, cytomegalovirus encephalgitis in a patient with HIV are known as?
Definition
opportunistic viral infections
Term
Peripheral nervous system consists of?
Definition
nerves and ganglia outside of the brain and spinal cord
Term
___________ is the main function of the PNS?
Definition
connect to the CNS
Term
PNS is divided into __________?
Definition
somatic nervous system and autonomic nervous system
Term
radiculopathies and radiculitis are disorders of?
Definition
spinal nerve roots
Term
Guillain-Barre syndrome is caused by immunologic reaction directed at?
Definition
peripheral nerves
Term
myasthenia gravis involves __________ muscles?
Definition
voluntary or striated
Term
Parkinson disease affects?
Definition
basal ganglia, degeneration of dopaminergic receptors
Term
Huntington affects?
Definition
basal ganglia, frontal cortex, depletion of GABA
Term
Multiple sclerosis affects?
Definition
CNS, demyelination
Term
ALS affects?
Definition
Scarring of corticospinal tract in lateral column of spinal cord, upper and lower motor neurons.
Term
Parkinson disease is caused by?
Definition
dopamine insufficiency, trauma infection, neoplasms, drugs and toxins
Term
Huntington disease is caused by?
Definition
autosomal dominant, chromosome 4
Term
Multiple sclerosis is caused by?
Definition
Immunogenetic viral, genetic, environmental, T cells become auto-reactive to myelin protein.
Term
ALS is caused by?
Definition
genetics, defective superoxide dismutase gene.
Term
Parkinson age onset?
Definition
>40, peaks in 60s
Term
Huntington age onset?
Definition
30s and 50s
Term
Huntington age onset?
Definition
30s and 50s
Term
Multiple sclerosis age onset is?
Definition
between 20 and 40
Term
ALS age onset ?
Definition
40s, peaks in 50s
Term
anencephaly is?
Definition
absence of skull and parts of the brain that results from early closure of the anterior neural tube
Term
encephalocele is?
Definition
herniation of the brain and meninges through a midline defect in the skull
Term
meningocele is?
Definition
protrusion of meninges through a vertebral defect
Term
Myelomeningocele is also known as?
Definition
spina bifida
Term
Myelomeningocele is?
Definition
herniation of the meninges, spinal fluid, spinal cord and nerves through a vertebral defect.
Term
Spina bifida occulta is?
Definition
Defect occurring in the lumbar or sacral area of the spine because of incomplete fusion of the vertebral laminae and is not visible to the naked eye.
Term
craniosynostosis is?
Definition
premature closure of cranial suture during the first 20 months of life.
Term
congenital hydrocephalus is?
Definition
increase in CSF volume, a defect in the reabsorption or a blockage of the ventricular drainage system
Term
cerebral palsy is?
Definition
static encephalopathy
Term
cerebral palsy is?
Definition
syndrome of motor disabilities that may be accompanied by mental retardation, seizures or both - is an assorted group of neurologic syndromes such as spasticity, ataxia, dyskinesia.
Term
PKU is?
Definition
encephalopathy caused by inherited metabolic disorder and is progressive in nature.
Term
Reye syndrome is?
Definition
acute encephalopathy believed to be caused by an interaction of aspirin, viruses and liver dysfunction.
Term
Lennox-Gastaut syndrome is a type of?
Definition
seizure disorder
Term
CNS consists of?
Definition
brain and spinal cord
Term
This part of the brain performs sensory, motor and reflex functions; controls cardiac, vasomotor and respiratory centers; centeral nerve reflex?
Definition
brain stem
Term
This part of the brain coordinates the activities of groups of muscles; maintains equilibrium; controls posture?
Definition
cerebellum
Term
This part of the brain deals with conscious recognition of crude pain, temperature and touch, relays sensory impulses (except smell) to cerebrum; emotions, arousal mechanism; complex reflex movements?
Definition
diencephalon thalamus
Term
This part of the brain links nervous system to endocrine system, corrdinates autonomic mnervous system controls body temperature, hunger thirst and sleep?
Definition
hypothalamus
Term
This part of the brain deals with voluntary control of sekeletal muscles, unconscious skeletal muscle movement, speaking and writing?
Definition
frontal
Term
This part of the brain deals with interpretation of odor and sound?
Definition
temporal
Term
This part of the brain deals with general body sensations?
Definition
parietal
Term
This part of the brain deals with sight?
Definition
Occipital
Term
This part(s) of the brain deals with memory; emotions; reasoning; intelligence?
Definition
all lobes
Term
This part of the brain deals with language, numeric skills; controlls right side of body?
Definition
left hemisphere
Term
This part of the brain deals with musical and artistic awareness; space and pattern perception; insight and controls the left side of the body?
Definition
right hemisphere
Term
contusions produce?
Definition
epidural hemorrhages, subdural hematomas and intracerebral hematomas
Term
contusion, extradural hematomas, subdural hematomas and intracerebral hematomas are all types of ____________?
Definition
traumatic brain injuries
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