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Neurodegenerative
Myasthenia Gravis, ALS, MS, Guillain-Barre (Terms & S/S)
7
Nursing
Undergraduate 2
06/01/2011

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Cards

Term
Myasthenia Gravis: S/S
Definition
-weakness of voluntary muscles
-weakness of muscles groups with ADL's
-respiratory weakness
-facial, eye drooping
-impaired swallowing, speaking, chewing

-gradual, subtle exacerbations and improvements up to 2 years before dx
(rare to affect lower extremities)
Term
Tensilon Test
Definition
-anticholinesterase is injected to boost acetylcholine at the junction

-if patient has MG, will have profound improvement of muscle use for 1-5 minutes
Term
Myasthenic Crisis: def, cause
Definition
-Sudden exacerbation of S/S of myasthenia gravis

-usually caused by infection/illness
-can be undermedicated or missed a dose
Term
Cholinergic Crisis: def, cause
Definition
-sudden weakness, including respiratory muscles

-patient is overmedicated with anticholinesterase meds
Term
ALS: S/S
Definition
-variable voluntary muscle weakness
-spasticity of limbs
-muscle wasting
-progresses to death
-starts distal and moves inward
Term
Guillain-Barre: S/S
Definition
-facial nerve loss
-weakness/inability to chew, swallow, speak
-HTN, hypotension, dysrythmias, sweating, paralytic ileus, urinary retention

* Degree of involvement varies from patient to patient
Term
Multiple Sclerosis: S/S
Definition
-fatigue*
-cognitive problems
-walking problems
-bowel/bladder problems
-visual disturbances
-depression
-tremors

(common for patients to relapse and remit)
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