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Neuroanatomy Final
N/A
136
Science
Undergraduate 3
06/02/2012

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Term
Types of Fibers
Definition
A Fibers
-large myelinated, rapid, typically motor
B Fibers
-smaller myelinated, slower, autonomic functions
c Fibers
-smallest and unmyelinated, slowest, severe pain, autonomic functions
Term
EPSP's
Definition
Excitatory Postsynaptic Potentials
-produced by binding of neurotransmitter molecules to receptors that result in the opening of channels (Na or K) or closing of channels producing DEPOLARIZATION
Term
IPSP's
Definition
Inhibitory Postsynaptic Potentials
-produced by binding of neurotransmitter molecules to receptors to increase permeability to CL or K causing HYPERPOLARIZATION
Term
Lower Motor Neuron Lesion Signs
Definition
Flaccid paralysis (no muscle tone), atrophy, deep tendon reflex absent
Term
Upper Motor Neuron Lesions Signs
Definition
spastic pralysis, little or no atrophy, hyperactive deep tendon reflex, pathological response present
Term
Reflex
Definition
subconscious stimulus--response mechanism--extremely important in diagnosis and localization of lesions
Term
Simple Reflex Arc
Definition
Includes: a receptor (special sense organ, cutaneous end organ, muscle spindle), the afferent neuron-->CNS-->interneuron-->efferent neuron-->effector
Term
Types of Reflexes
Definition
1. Superficial--skin, mucous membrane
2. Deep Tendon---myotatic
3.Visceral--organic
4.Pathologic--abnormal
Term
Stretch Reflexes
Definition
provide feedback mechanism for maintaining appropriate muscle tone
depends on:
-specialized sensory receptors (muscle spindles)
-afferent fibers
-2 types of LMNs (alpha and gamma)
-specialized inhibitory interneurons (Renshaw cells)
Term
CSF Functions
Definition
-supports weight of the brain, prevents it from resting on the bottom of the skull
-cushions/dampens during running and walking
-provides a stable chemical environment
Term
CSF produced by?
Definition
Choroid plexus (60%) and Ependyma cells in subarachnoid space (40%)
Term
Mechanisms of CSF circulation
Definition
Drift, Oscillation, pulsative movement
Term
Meningitis
Definition
Inflammation of the coverings of the brain
Bacterial: can be lethal, very rare
Viral:not as rare, not life threatening, sever head pain, fever incredible fatigue
Term
Types of Hemorrhages
Definition
Hypertensive: damages tissue and can be extremely damaging
Subarachnoid: bleeding into subarachnoid space, can be due to physical injury like blow to the head
Subdural: violent movement can tear subdural tissue, blood pumps into the space and can become under pressure
Epidural: something goes through skin and cranium, not as contained so pressure build-up doesn't occur
Vascular Malformations: blood vessel doesn't form right, keeps growing and can tear causing bleeding
Term
Motor Control Heiarchy
Definition
1. Reflexes- simple, occur at spinal level
2. Repetitive Movements- controlled by CPG's (walking running etc)
3. Goal Oriented Movements- ie manipulation of objects
Term
Area 4
Definition
Primary motor area
Term
Area 6
Definition
Premotor area
Term
Area 8
Definition
frontal eye field, concerned with eye movements
Term
Area 44, 45
Definition
Broca's area, motor aspects of speech
Term
Area 17
Definition
primary visual cortex
Term
Areas 18, 19
Definition
visual association areas within the occipital lobe
Term
Area 41
Definition
primary auditory cortex
Term
area 42
Definition
auditory association cortex
Term
Wernicke's Area
Definition
Posterior part of 22, plays an important role in the comprehension of language
Term
Pain Pathways
Definition
Lateral Spinothalamic Tract: sharp, stabbing pain
Spinoretiuculothalamic Tract: deep, poorly localized, burning pain
Term
Cranial Nerves:
Special Sensory Input
Definition
I, II and VIII
Term
Cranial Nerves:
Eye movements and pupillary constriction
Definition
Nerves III, IV, and VI
Term
Cranial Nerves:
Pure motor
Definition
XI (sternocleidomastoid and trapezius) and XII (muscles of the tongue)
Term
Cranial Nerves:
Mixed
Definition
V, VII, IX, and X
Term
Cranial Nerve I
Definition
Olfactory Nerve
Term
Cranial Nerve II
Definition
Optic Nerve
Term
Cranial Nerve III
Definition
Oculmotor Nerve
Term
Cranial Nerve IV
Definition
Trochlear Nerve
-the only crossed cranial nerve
Term
Cranial Nerve VI
Definition
Abducens Nerve
Term
Cranial Nerve V
Definition
Trigeminal Nerve
Term
Cranial Nerve VII
Definition
Facial Nerve
Term
Cranial Nerve VIII
Definition
Vestibulocochlear Nerve
Term
Cranial Nerve IX
Definition
Glossopharyngeal Nerve
Term
Cranial Nerve X
Definition
Vagus Nerve
Term
Cranial Nerve XI
Definition
Accessory Nerve
Term
Cranial Nerve XII
Definition
Hypoglossal Nerve
Term
rhodopsin
Definition
the visual pigment within retinal rods
Term
Magnocellular Ganglion cells
Definition
A retinal ganglion cell that has a larger diameter axon, faster conduction velocity, and are sensitive to motion but not to color, details or form
Term
Parvocellular Ganglion cells
Definition
A retinal ganglion cell with a smaller diameter axon, slower conduction velocity that conveys info about form and color
Term
Limbic System
Definition
subserves basic survival functions that include feeding behavior, fight-or-fight response, aggression, the expression of emotion and autonomic, behavioral and endocrine aspecs of the sexual response
Term
Anosmia
Definition
absence of smell, usually due to nasal infections
head trauma can cause it as well as a result of injury to the cribiform plate damaging the olfactry nerve, bulb or tract
Term
fornix
Definition
arched white fiber tract extrnding from the hippocampal formation to the diencephalon and septal area.
-carries some incoming axons into the hippocampus, and major outflow pathway from the hippocampus
Term
The Papez Circuit
Definition
Ties together the cerebral cortex and the hypothalamus
-provides an anatomic substrate for the convergence of cognitive (cortical) activities, emotional experience, and expression
Term
Anterior Commissure
Definition
Band of white fibers that crosses the midline to join both cerebral hemispheres.
-Contains two fiber systems: Interbulbar system (joins both ofactory nuclei) and intertemporal system (connects the temporal lobe areas of both cerebral hemispheres).
Term
Amygdala
Definition
Plays an important rile in establishing associations between sensory inputs and various affective states.
-also participates in regulating endocrine activity, sexual behavior, food and water intake.
Term
Septal Area
Definition
Part of Limbic system
-relatively large in animals like cats and rats
-mediates sensations of self-stimulation or self-reward
-may play a role in the euphoric feeling from narcotics
Term
Three types of memory
Definition
immediate recall, short-term memory, and long term memory
Term
Anterograde Amnesia
Definition
No new long-term memories can be extablished
-hippocampus is resonsible for converting short term to long term memory
Term
Hippocampus
Definition
-converts short term memory to long term memory
-important for spatial problem solving
Term
Kluver-Bucy Syndrome
Definition
-this occurs in patients with bilateral temporal lobe lesions
-major characteristics include: hyperorality (explore objects by placing in mouth etc), hypersexuality, psychic blindness (objects no longer recognized), personality changes
Term
Temporal Lobe Epilepsy
Definition
-Seizures that originate in this area are called psychomotor seizures
-may include: abnormal sensations, esp bizarre olfactory sensations, repeated involuntary movements such as chewing, lib smacking etc, disorders of consciousness, memory loss, hallucinations and disorders of recall and recognition
Term
Tonotopia
Definition

Precise localization of high-frequency to low-frequency sound wave transmission -exists along the entire pathway from cochlea to auditory cortex

 

Term
Tinnitus
Definition
Ringing, buzzing, or hissing in the ear
-frequently an early sign of peripheral cochlear disease
Term
Otosclerosis
Definition
-Common cause of hearing loss in adults
-progressive ossification of the ligaments between the ossicles
Term
Autonomic Nervous System targets:
Definition
-cardiac tissue
-smooth muscle tissue (like in G.I. tract)
-glands
Term
Similarities between Sympathetic and Parasympathetic nervous systems
Definition
-both are efferent, two-neuron systems with a pre-ganglionic and postganglionic neuron
Term
Differences between Sympathetic and Parasympathetic nervous systems
Definition
-location of preganglionic neuron, and length of pre and postganglionic neurons
Term
Horner's Syndrome
Definition
-unilateral enophthalmos, ptosis, miosis, and loss of sweating over the ipsilateral half of the face or forehead
-from interruption of the sympathetic pathways to the eye and orbit or in the coratid plexux
Term
Raynaud's Disease
Definition
-Affects the toes, the fingers, the edges of the ears, and the tip of the nose and spreads to involve large areas
-Disorder of the peripheral vascular innervation
Term
Causalgia
Definition
-a painful condition of the hands or feet characterized by severe burning pain, glossy skin, swelling, redness, sweating, trophic nail changes.
-Caused by irritation of the median or sciatic nerve through injury
Term
Hirschsprung's Disease (megacolon)
Definition
-marked dilation of the colon, accompanied by chronic constipation
-it is associated with congenital lack of parasympathetic ganglia and abnormal nerve fibers in an apparently normal segment of large bowel
Term
Baroreceptors
Definition
sensory receptors, stimulated by pressure, are located in the aortic arch and carotid sinus
Term
Chemoreceptors
Definition
sensitive to hypoxia are located in the aorta and carotid bodies
Term
vergence
Definition
fixating on a single point
Term
Miosis vs. mydriasis
Definition
Miosis=constriction, due to stimulation of parasympathetic fibers
mydriasis=dilation, sympathetic activation
Term
Nasal vs. Temporal Retinal fields
Definition
Nasal: decussates at chiasm
Temporal: ipsilateral
Term
1st, 2nd, 3rd order neurons of the Visual System
Definition
1st- Rods and Cones
2nd- Bipolar Cells
3rd- Ganglion cells
Term
Where is the occlusion?
-motor control loss in R ride of face, arm, hand
-inability to speak
-contralateral hemiplegia
Definition
Left middle cerebral artery occlusion
Term
Where is the occlusion?
-dysfunction in left leg, prob cant walk
-motor and sensory
Definition
Right anterior cerebral artery occlusion
Term
Lateral Corticospinal Tract
Definition
-Fine motor functions
-Modulation of sensory functions
-Originates: motor and premotor cortex
-Ends: anterior horn neurons
Term
Anterior Corticspinal Tract
Definition
-Gross and postural motor function
-Originates: motor and premotor cortex
-Ends: anterior horn neurons- interneurons and LMN's
Term
Vestibulospinal Tract
Definition
-Postural reflexes
-Origin: lateral and medial vestibular nucleus
-Ends: gamma and alpha motor neurons
Term
Reticulospinal
Definition
-Modulation of Spinal reflexes
-Origin: brain stem reticular formation
-End: dorsal and ventral horn gamma motor neurons
Term
Dorsal Column System
Definition
-Fien touch, proprioception, two point discrimination
-Origin: skin, joints, tendons
-Ends: thalamus
Term
Lateral Spinothalamic
Definition
-Sharp pain and temperature
-Origin: skin
-End: thalamus
Term
Anterior Spinothalamic
Definition
-Crude touch
-Origin: skin
-End: thalamus
Term
Rubrospinal Tract
Definition
-Motor function--flexor muscles
-Origin: red nucleus (midbrain)
-Ends: ventral horn interneurons
Term
Tectospinal
Definition
-reflexive head turning
-Origin: midbrain
-End: ventral horn interneuron
Term
Functions of hypothalamus
Definition
1. appetite
2. water balance
3. anterior pituitary function
4. body temp
5. autonomic functions
6. expression of emotion
Term
Where is the occlusion?
-dysphagia
-vertigo/nystagmus
-hoarseness when speaking
-possible vocal cord paralysis
-taste loss on ipsilateral side of tongue
Definition
R/L posterior cerebellar artery occlusion
Term
Where is the occlusion?
-ipsilateral facial paralysis
-taste loss on ipsilateral side of tongue
-deafness, ringing in ears
Definition
R/L Anterior Cerebellar Artery occlusion
Term
Top Down vs. Bottom Up
Definition
Top Down: recieves info from higher order, goal oriented
Bottom Up: information travels from a lower order, via dorsal column tract or spinocerebellar info about movement, position etc
Term
Dorsal/ Ventral Spinocerebellar Tract
Definition
-Movement and position mechanisms
-Origin: muscle spindles, GTO's, touch and pressure receptors
-End: cerebellar paleocortex
Term
Static Labrynth
Definition
-gives info re position of head in space
-includes: saccule and utricle
otopliths: located here, small calcium carbonate crystals, they displace the hair cell processes and excite the utricle and saccule in response to horizontal and verticle movement
Term
Kinetic Labrynth
Definition
-provides information about rotation
-consists of 3 semicircular canals
Term
Vestibulo-ocular Reflex
Definition
When the head moves, a compensatory adjustment of gaze is required to keep the eyes fixated
Term
Olivocochlear Bundle
Definition
modulates the sensitivity of the cochlear organ
Term
Parvocellular Ganglion cells
Definition
-Receive color-specific signals from 3 types of cones and relay them to the brain via the optic nerve
Term
Static Labrynth
Definition
-gives info re position of head in space
-includes: saccule and utricle
otopliths: located here, small calcium carbonate crystals, they displace the hair cell processes and excite the utricle and saccule in response to horizontal and verticle movement
Term
Kinetic Labrynth
Definition
-provides information about rotation
-consists of 3 semicircular canals
Term
Vestibulo-ocular Reflex
Definition
When the head moves, a compensatory adjustment of gaze is required to keep the eyes fixated
Term
Olivocochlear Bundle
Definition
modulates the sensitivity of the cochlear organ
Term
Parvocellular Ganglion cells
Definition
-Receive color-specific signals from 3 types of cones and relay them to the brain via the optic nerve
Term
Where is the occlusion?
-ipsilateral facial paralysis
-taste loss on ipsilateral side of tongue
-deafness, ringing in ears
Definition
R/L Anterior Cerebellar Artery occlusion
Term
Top Down vs. Bottom Up
Definition
Top Down: recieves info from higher order, goal oriented
Bottom Up: information travels from a lower order, via dorsal column tract or spinocerebellar info about movement, position etc
Term
Dorsal/ Ventral Spinocerebellar Tract
Definition
-Movement and position mechanisms
-Origin: muscle spindles, GTO's, touch and pressure receptors
-End: cerebellar paleocortex
Term
Static Labrynth
Definition
-gives info re position of head in space
-includes: saccule and utricle
otopliths: located here, small calcium carbonate crystals, they displace the hair cell processes and excite the utricle and saccule in response to horizontal and verticle movement
Term
Referred Pain
Definition
-Misinterpretation of the source
-incoming afferents at the same segmental level, neurons in grey matter get over stimulated causes referred pain
Term
Fovea
Definition
-high density of cones
-focal vision is located here
Term
What Are the 6 ocular muscles?
Definition
1. Lateral rectus
2. Medial rectus
3. superior rectus
4. inferior rectus
5. superior oblique
6. inferior oblique
Term
Vestibular Pathway
Definition
1st order: Vestibular ganglion
2nd Order: vestibular nuclei in brain stem
Function: participates in the perception of control and balance
Term
Nystagmus
Definition
Rhythmic, oscillating motions of the eyes are
Term
Chain Ganglia
Definition
parallel to spinal cord, collection of cell bodies in the periphery
Term
Differences between para/sympathetic postganglion lengths
Definition
Parasympathetic: very short, often times in affector organ
Sympathetic: very long, leaves chain ganglia all the way to organ
Term
3 Pathways for Preganglionic sympathetic fibers?
Definition
1. Chain Ganglia-->synapses with about 32 post-synaptic fibers, it can reenter a spinal nerve
2. Greater/Lesser splanchnic nerves-->collateral ganglia without synapsing
3. Adrenal medulla, goes directly there without synapsing
Term
In what kind of conditions do you get a parasympathetic response? Sympathetic?
Definition
Parasympathetic: maintains body functions in "quiet" conditions
Sympathetic: prepares the body for strenuous, intense exercise
Term
Direct Perception (visual)
Definition
Visual perception drives action directl
-no higher order cognitive processing is required
-not the same as a reflex
-this is counter to "information processing" models of behavior
Term
Axodendritic Synapse
Definition
axon-->dendrite
usually excitatory
Term
Axosomatic Synapse
Definition
axon-->cell body
usually inhibitory
Term
Axoaxonic Synapse
Definition
axon-->axon
usually modulatory, presynaptic inhibition
Term
Dendrodendritic Synapse
Definition
dendrite-->dendrite
can be either
Term
Anencephaly
Definition
Failure of the neural tube to close at the cranial end
-this is a type of maldevelopment incompatible with life
Term
Sbina Bifida
Definition
Failure of close at the cuadal end--associated with maldevelopment of the vertebrae
Term
Muscle spindles
Definition
specialized mechanoreceptors located within the muscle that provides info about length and rate of chnge in length of the muscle
-distributed in parallel with extrafusal muscle fibers
Term
Alpha Motor Neurons
Definition
-large, anterior horn neurons that innervate extrafusal muscle fibers and cause muscle contraction
-excitatory effects
-larger diameter, fast conduction
Term
Gamma Motor Neurons
Definition
-small, specialized motor neurons whose cell bodies are located in the ventral horn
-they innervate intrafusal fibers in muscle spindles to contract
-relatively small acons
-firing of gamma neurons increases muscle tension on muscle spindle which increases sensitivity to overall stimulus
they regulate postural tone
Term
Renshaw Cells
Definition
-interneurons located in the ventral horn, project to alpha motor neurons
-inhibitory
-they recieve excitatory input from collaterals that branch from alpha motor neurons
-prevent overactivity of alpha motor neurons
Term
Golgi Tendon Organs
Definition
-receptors located in muscle tendons
-stretch receptors are arranged in series with extrafusal fibers and are activated by stretching/ contracting
-they mediate the inversal stretch reflex
-prevent overactivity of alpha motor neurons
Term
Internal Carotid Artery occlusion
Definition
Can be asymptomatic, why?
Collateral blood flow
Term
Two major functions of the cerebellum
Definition
coordination of voluntary motor activities, and control of equilibrium and muscle tone
Term
Gate theory of pain
Definition
the strength of synaptic transmission at these junctions is decreased (probably by presynaptic inhibition) when large, non-pain signaling, axons within the nerve are excited (the gate closes).
Term
Gate theory of pain
Definition
the strength of synaptic transmission at these junctions is decreased (probably by presynaptic inhibition) when large, non-pain signaling, axons within the nerve are excited (the gate closes).
Term
Transverse fibere
Definition
commussural
-they connect the two cerebral hemishperes
Term
Projection Fibers
Definition
connect the cerebral cortex with the lower parts of the brain or spinal cord
Term
Association Fibers
Definition
-these fibers connect the various portions of the cerebral hemisphere and permit the cortex to function as a coordinated whole
Term
Pyrimidal cells
Definition
-shaped like a teepee, with an apical dendrite reaching the upper end toward the cortical surface, and basilar dendrites extending horizontally from the body
Term
Stellate Neurons
Definition
-star shaped, with dendrites extending in all directions
Term
Fusiform Neurons
Definition
-found in deeper layers, with a large dendrite that ascends toward the surface of the cortex
Term
Channelopathies
Definition
-Something wrong with the influx/eflux of pain
Term
Treatments of pain
Definition
-endorphins
-medication
-accupuncture
-T.E.N.S.
-Spinal cord stimulation
-surgery
-placebos
A
Term
Arachnoid Granulation
Definition
-sit of absorption of CSF
-consist of many microscopic villi
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