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Neuro test 2
Neuro
83
Health Care
Not Applicable
11/03/2012

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Term
alpha motor neurons
Definition
have renshaw cells that turn and inhibit the same neuron
Term
flacidity
Definition
complete loss of muscle tone
Term
UMN
Definition
only found within the CNS,ussually affects groups of muscle
Term
corticospinal tract
Definition
any motor signals to the trunk or periphery
Term
corticobulbar tract
Definition
facial and jaw movement
Term
primary motor cortex
Definition
made up of the precentral gyrus (area 4) and
the rostral half of the paracentral lobule.
•most important role is control, skilled voluntary
movements, of the contralateral limb musculature,
with some regulation of axial and proximal muscles.
Term
premotor cortex
Definition
(has to go through primary motor cortex)
•located rostral to precentral gyrus, (areas 6 and 8), projects to brainstem reticular formation.
•area 8 = frontal eye field: involved in control of eye movements. Problem if one of your eyes move even a little bit differently
•especially for control of axial muscles and proximal limb muscles, and in orienting the body toward a target.
Term
supplementary motor cortex
Definition
function important in sequencing movements (including bilateral patterns).
•both premotor and supplementary cortex project to the primary cortex
Term
lateral cortiospinal tract
Definition
especially involved with skilled movement
Term
anterior corticospinal tract
Definition
mostly for the control of axial muscles
Term
lateral corticospinal fibers from the parietal
Definition
lobe form a reflected feedback pathway for modulating sensory input. Is some ability for cells to reflect and go to the sensory system
Term
indirect corticobulbar fibers
Definition
these interneurons then act upon motor nuclei of CNs III, IV, V, VI, VII, & XII.
3,4,6 eye movements, jaw, facial, tounge movements, forehead – is dual control, bilateral innervation
Term
direct corticobulbar fibers
Definition
: from cerebral cortex, descend in genu of internal capsule and then pass crossed and uncrossed to bilateral lower motoneurons of CN V (mastication), VII (facial), XII (tongue).
Term
facial muscles below eye level
Definition
are innervated only by crossed corticobulbar fibers. unilateral
Term
corticoreticulospinal pathway
Definition
important autonomic link to the spinal cord
Term
vestibulospinal tracts
Definition
esp important for tone and posture, exerts excitatory and inhibitory influences on motoneurons innervating neck and back muscles
Term
medial longitudinal fasciculus
Definition
descending components include the medial vestibulospinal, medial reticulospinal, and tectospinal.
•ascending component is the vestibuloocular reflex pathway in the pons and midbrain, originates from vestibular nuclei cells and extends from the region of abducens nucleus to the oculomotor nucleus. important for conjugate eye movements.
Term
corticotectal and tectospinal tracts
Definition
associated with reflexive eye, head and neck movements in response to visual and vestibular inputs.
Term
transduction
Definition
conversion of sensory stimuli into a nerve impulse
Term
spinotectal tract
Definition
probably modulates pain, and integrates visual and somatic sensation for orienting head and body
Term
spinoreticular tract
Definition
conveys diffuse, poorly localized pain from somatic and visceral areas.
•input is applied toward autonomic and reflex responses to pain and affective-motivational responses
Term
thalamus
Definition
awareness of pain is centered in the
Term
somatosensory areas
Definition
the quality of pain is processed by
Term
post central gyrus parietal lobe
Definition
localization of pain occurs in the
Term
tractotomy
Definition
transection of pain tracts resulting in contralateral loss of pain sensation 1-2 levels lower
Term
lemniscal system
Definition
the major pathway for stimuli contributing to kinesthetic sense and stereognosis.
•carries DGS Stimuli from the body, limbs, and back of head.
Term
fasiculus gracilis
Definition
- contains sacral, lumbar, and lower six thoracic spinal levels (incl lower extremities). The longest neurons in the body
Term
fasiculus cuneatus
Definition
contains the upper six thoracic, & cervical levels (upper extremities & back of head).
Term
lemniscal system and trigeminothalamic tract
Definition
DGS pathways
Term
lateral and anterior spinothalamic tract
Definition
2 components of the ALS
Term
ALS,medial lemniscal pathway, spinocervical thalamic pathway,the trigeminothalamic tract (for anterior head), spinocervicothalamic pathway (lateral cervical system)
Definition
pathways associated with light touch
Term
psterior spinocerebellar tract
Definition
carries info from muscles and joints of the _lower limb_ and lower half of the body.
•feedback regarding the resulting movement
Term
cuneocerebellar tract
Definition
•carries info from the _upper limb____ of the body and the upper limbs.
Term
anterior spinocerebellar tract
Definition
prob conveys __feed foward__ signals about the quant and qual of descending “planned” motor activity
Term
retrospinocerebellar tract
Definition
•probably conveys internal feedback signals about the quant and qual of descending motor activity
Term
spinocervicocerebellar, spinoolivocerebellar
Definition
indirect proprioceptive pathways
Term
rhomberg test
Definition
standing erect with feet close together causes swaying when eyes are closed
Term
a nerve fiber can only transmit impulses.
•the site of the terminus of the fiber determines the type of sensation experienced
Definition
“labeled line” principle or “law of specific nerve energies”.
Term
pacinian corpuscles
Definition
adapt most rapidly to stimuli
Term
cerebellum
Definition
acts to _adjust / regulation_ the activity of the cortical and brainstem motor centers
Term
muscle spindle
Definition
a fusiform stretch receptor (3-4 mm) located within a muscle belly. Made of a capusle that has 2-12
Term
. the nuclear bag fibers: longer and larger type with a _cluster_ of nuclei in a central enlargement.
2. the nuclear chain fibers: thinner and shorter, with the nuclei lined up in a _ row, center of fiber__.
Definition
2 kinds of intrafusal fibers
Term
clonus
Definition
oscillation of a muscle jerk reflex. Usually see it at the ankle, sudden contraction that pushes the ankle back down. Boucing of the foot, DF and PF, a form of hyper tonus
Term
gama reflex loop
Definition
•contributes to the fine adjustments of muscle activity
Term
golgi tendon reflex
Definition
If a muslce is working to hard it stimulates it to stop, safety feature
•they also facilitates antagonist muscle contraction
Term
muscle tone
Definition
the degree of contraction by a muscle at rest, without conscious effort; tested by passive movement
Term
syringo myilia
Definition
hole in the cervical cord developes, spinothamic tract, loss of pain and temp in contralateral and ipsilateral, 6-8 no problems with sensory loss at C5 or T1. Only where the damage occurs is there damage.
Term
tabis dorsalis
Definition
descrimintive general senses, bilateral proprioception loss upper and Lower extremeties, especially lower
Term
brown sequard syndrom
Definition
Hemisection – affect one complete side of the spinal cord
Important to know what part ot the cord and where at
C7-T2: dorsal roots and ventral roots wouldn’t be functioning,
Term
pyramial system
Definition
direct link to LMNs; consists of corticobulbar and corticospinal tracts
Term
extrapyramidal system
Definition
indirect link to LMNs; includes corticoreticulospinal and corticorubrospinal pathways, including connections with cerebellum and basal ganglia
Term
pars compacta
Definition
dorsal deeper part of the substantia nigra,goes to striatum, contains melanin, & produces_dopamine__
Term
pars reticularis
Definition
goes directly to the thalamus
Term
striatum
Definition
makes up the input nuclei, receiving major input as excitatory from cerebral cortex.
Term
GP (lateral), subthalamic, substantia nigra (pars compacta), and ventral tegmental area
Definition
make up the intrinsic nuclei, mostly inhibitory neurons.
Term
GP (medial), substantia nigra (pars reticularis), and ventral pallidum
Definition
make up the output nuclei
Term
parkinsons disease
Definition
characterized by cog-wheel releases intermittently as you’re pulling the arm out_ and resting tremor.
•difficulty initiating movement.
•shuffling gait with short _festinating__ steps. Weight bearing more on the forefoot, forward flexed position almost like they are walking just to not fall over,
masked face”: flat, expressionless face, with no expression. Can’t produce dopamine
•nigrostriatal degeneration with reduced or absent dopamine.
•medical treatment with L-dopa (precursor of dopamine).
Term
tardive dyskinesia
Definition
sometimes occurs with use of antipsychotic phenothiazines.
•includes facial _grimace_, lip smacking, choreoathetotic movements.
•treatment is to terminate use of the drug.
Term
choreas
Definition
: irregular, _brisk_, but graceful movements, esp in _distal___ extremity musculature.
•often with involuntary facial grimace
Term
athetosis
Definition
slow, _writhing_ “wormlike” involuntary movements, worsened with voluntary movement.
•facial grimace may accompany the alternating agonist and antagonist activity.
•may follow striatum, esp putamen, lesions.
•often seen with cerebral palsy.
Term
ballismus
Definition
violent, _flalling_, involuntary movements mainly in proximal girdle musculature.
•esp with lesions of contralateral subthalamus = One-sided: can be very sudden movement
Term
inferior cerebellar peduncle
Definition
bridges the cerebellum and the medulla (impulses directly from cord).
Term
middle cerebellar peduncle
Definition
the largest, bridges the basilar pons and the cerebellum.
Term
superior cerebellar peduncle
Definition
- bridges the midbrain and the cerebellum. Double crossers
Term
flocconodular lobe
Definition
: two flocculi which extend laterally near the lateral recess, connected medially by the nodulus. [regulating _muscle tone_, equilibrium and _posture_ (axial muscles)].
Term
anterior lobe
Definition
: small portion rostral to the primary fissure, receives proprioception and exteroception. [important in regulating muscle _tone_].
Term
posterior lobe
Definition
large portion between the primary fissure and the posterolateral fissure. It receives input from the cerebral cortex. [important role in programming and __coordination_ movements].
Term
climbing fibers
Definition
olivocerebellar fibers are excitatory directly on contralateral Purkinje cells.
Term
mossy fibers
Definition
: from spinal cord, vestibular and brainstem nuclei are excitatory on granule cells.
Term
molecular layer
Definition
superficial layer, containing stellate cells and basket cells.
axons of these cells are at 90° to the long axis of the folium & parallel to the surface.
Term
purkinje layer
Definition
- thin, middle layer, containing large Purkinje cell bodies.
-Purkinje cell dendritic tree in molecular layer, perpendicular to the long axis of the folium.
Term
granular layer
Definition
deep layer, including cell bodies of granule cells and golgi cells.
Term
climbing fibers
Definition
directly excite purkinje cells
Term
purkinje axons
Definition
inhibit deep cerebellar nuclei
Term
mossy fibers
Definition
excite granule cells
Term
posterior spinocerebellar, cuneocerebellar, retrospinocerebellar tracts (all uncrossed)
Definition
input into the cerebellum
Term
juxtarestiform body
Definition
just medial to the inferior cerebellar peduncle contains vesibulocerebellar fibers from vestibular nuclei, carries fastigobulbar to the vestibular nuclei
Term
basket and stellate cells
Definition
send inhibitory stimuli to Purkinje cells
Term
granule cells
Definition
excite golgi cells which inhibit other granule cells in the area.
Term
vestibulocerebellum: the _flooculonodular_ lobe
Definition
•input from the vestibular receptors through vestibular nuclei and vestibular nerve directly.
•flocculonodular lobe projects to fastigial nucleus which projects to vestibular nuclei
•maintain equilibrium and coordinate head and eye movement.
Term
spinocerebellum:
a. median zone (vermis):
Definition
based upon somatosensory input from the body and head (post spinocerebellar, cuneocerebellar, trigeminal), vermal cortex projects to fastigial nucleus (projects to the reticular nuclei to impact the reticulospinal tracts, with a few of these fibers ascending to VL thalamus, which then projects to primary motor cortex to impact the anterior corticospinal tract.
•these specific medial descending pathways with vermal origins terminate in the medial spinal gray for control of _axial_ and girdle movement (i.e. posture)
Term
spinocerebellum: b. paramedian zone (paravermis):
Definition
somatosensory (same as above) to paravermis, with fibers terminate on red nucleus (rubrospinal) or VL thalamus which then projects to primary motor cortex (lateral corticospinal tract).
•these lateral descending pathways control the extremity musculature for limb movement.
Term
cerebrocerebellum (neo): the lateral hemisphere
Definition
primarily input from the cerebral cortex, motor and somatosensory, through corticopontine fibers.
•the pontocerebellar fibers decussate, pass thru the middle cerebellar peduncle to lat hemisphere.
•Purkinje fibers project to dentate nucleus whose fibers ascend thru sup cerebellar peduncle.
-some will decussate to red nucleus for rubroolivary which acts upon olivocerebellar climbing fibers and has rubrospinal fibers which decussate to run contralateral to original cerebrum.
-others will decussate to ascend to VL, then to primary motor cortex for lateral corticospinal tract
•functions in planning and _coordinating_ movement of ipsilateral limbs. Why does it say ipsilateral? Right cerebellum signal to the opposite, the cortex is going to cross back to the side it started on, cerebllum is ipsillateral control
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