Term
|
Definition
3 of the 7 for 1yr or more
Tolerance
Withdrawl
Larger ammounts
Cut Down
Increased time used for the drug
Loss of Social/Occupational activities
Use despite Pschological/Health impairment |
|
|
Term
| What are the types of tolerance |
|
Definition
Pharmokinetics
Pharmodynamics
Behavioral
Inverse Tolerance |
|
|
Term
| What are the variables that generate addiction |
|
Definition
The drug is:
Euphoric
Fast onset
Increase Dopamine
The User has:
Genetic Suseptibility
Biological parent addict
Pysch disorder
Environment is:
Acceptance of Use
Economics |
|
|
Term
| What are the physical and behavioral effects caused by dopamine in stimulants use |
|
Definition
Euphoria(Accumbens)
Stereotyped Behavior(Caudate-Putamen)
Vigilence/Attention(Limbic Cortex)
Sympathetic Stimulation |
|
|
Term
| What are the adverse behavioral effects of chronic high dose cocaine |
|
Definition
|
|
Term
| What is the duration of of action of cocaine |
|
Definition
|
|
Term
| Does cocaine exhibit tolerance or sensitization |
|
Definition
|
|
Term
| What are the fetal effects of maternal cocaine use |
|
Definition
| motor and cognitive impariment from ischemic cerebral effects |
|
|
Term
| What is the mechanism of the psychodelics |
|
Definition
| partial Agonism at 5HT2a and 5HT2c |
|
|
Term
|
Definition
| Noncompetitive block of NMDA associated Ca channel |
|
|
Term
| What are the physiological roles of CB1 and CB2 |
|
Definition
CB1: (Brain) Analgesia, Catalepsy
CB2: (Peripheral) Anti-Inflammatory |
|
|
Term
|
Definition
| CB1 and CB2 which are g-protein coupled receptors which inhibit cAMP release |
|
|
Term
| What are drugs similar to THC used medically and what are they used for |
|
Definition
Dronabinol: antinausea and antiemetic
Levonantradol: Analgesic, Antispasmodic |
|
|
Term
| What are the medical uses of THC? |
|
Definition
Anorexia
Antiemetic
Analgesic
Movement Disorder |
|
|
Term
| What is the mechanism of alcohol? |
|
Definition
Inhibition of NMDA receptor
Enhances GABA-A and 5HT3 on GABAnergic neurons |
|
|
Term
| What does tolerance to alcohol also convey tolerane to? |
|
Definition
|
|
Term
| What is the types of tolerance generated to alcohol |
|
Definition
Pharmmodynamic
Pharmokinetic
Behavior |
|
|
Term
| Treatment of alcohol withdrawl |
|
Definition
|
|
Term
| What effects of benzodiazepines do not exhibit tolerance |
|
Definition
|
|
Term
| How are benzodiazepines most commonly abused |
|
Definition
Potentiate other drugs or
Reduce side effects of other drugs |
|
|
Term
| What drugs can be used to treat benzodiazepine withdrawal and what drug is used to treat benzo toxicity |
|
Definition
Withdrawal: Anticonvulsants
Overdose: Flumazenil |
|
|
Term
|
Definition
|
|
Term
| What is the diagnosis for substance abuse |
|
Definition
One or more of the following
Use causes failure to fullfill obligations
Use causes legal problems
Use in Physically Hazardous Situations
Use despite social/interpersonal problems |
|
|
