Term
|
Definition
| azotemia + metab effects from accumulation of toxic chemical products |
|
|
Term
|
Definition
| acute onset hematuria, hypertension, edema, azotemia |
|
|
Term
|
Definition
| heavy proteinuria (>3.5), hypoalbuminemia, hyperlipidemia, edema, lipiduria |
|
|
Term
|
Definition
| recent onset azotemia w/oliguria or anuria |
|
|
Term
| describe the components of the BM of a glomerulus |
|
Definition
| type IV collagen, laminin, anionic heparan sulfate proteoglycan |
|
|
Term
| linear immunofluorscence pattern indicates |
|
Definition
| anti-GBM disease i.e. goodpastures |
|
|
Term
| lumpy bumpy immunofluorsence indicates |
|
Definition
| immune complex deposition in glomerulus |
|
|
Term
|
Definition
| anti-GBM i.e. goodpasture's |
|
|
Term
|
Definition
|
|
Term
|
Definition
| pauci-immune; ANCA-assoc i.e. Wegener Granulomatous, polyarteritis nodosa |
|
|
Term
| What nephropathy occurs ~1 wk after an URT infection? |
|
Definition
| Berger's Disease (IgA Nephropathy) |
|
|
Term
| What nephropathy is characterized by episodic hematuria? |
|
Definition
|
|
Term
| What nephropathy mimics IgA nephropathy, but is characterized by nonmigratory arthralgia? |
|
Definition
|
|
Term
| What are the characteristics of HSP? |
|
Definition
| young children, renal abn, purpura, abd pain and/or bleeding, nonmigratory arthralgia |
|
|
Term
| What nephritic syndromes decrease complement? |
|
Definition
| Post-infectious, glomerulonephritis w/endocarditis, lupus nephritis |
|
|
Term
| What nephrotic syndromes exhibit diffuse loss of foot processes? |
|
Definition
|
|
Term
|
Definition
|
|
Term
| What nephrotic syndrome is prone to DVT? |
|
Definition
|
|
Term
| What nephropathy is associated with subepithelial spikes and capillary wall thickening? |
|
Definition
|
|
Term
| An African American with HT, LL Edema, HIV and renal insufficiency? |
|
Definition
|
|
Term
| What are the mechanisms of proteinuria? |
|
Definition
| loss of glomerular polyanions, hyperfiltration to compensate for decreased GFR, immune-mediated injury |
|
|
Term
|
Definition
|
|
Term
| Which nephrotic syndromes are assoc with hepatitis? |
|
Definition
| membranous, membranoprolif, post-infectious |
|
|
Term
|
Definition
| type II membranoporliferative glomerulonephritis (intramembranous deposits) |
|
|
Term
| What glomerulonephritidies most commonly affect children? |
|
Definition
| post infectious, MCD, IgA, HSP |
|
|
Term
| what condition is assocaited w/nonmigratory arthralgia |
|
Definition
|
|
Term
| how do you treat membranous nephropathy? |
|
Definition
| protein-reducing drugs: ACEi, ARBs, statins, steroids, cyclphosphamide, MMF, and anti-coag |
|
|
Term
| Which nephrotic syndrome is assoc w/Hep B? |
|
Definition
|
|
Term
| Which nephrotic is assoc w/Hep C? |
|
Definition
|
|
Term
| How do you treat membranoprolifative glomerulonephritis? |
|
Definition
| steroids and cyclophosphoamide |
|
|
Term
| Which type of diabetes patients more often progress to dialysis? |
|
Definition
|
|
Term
| How can amyloidosis be diagnosed? |
|
Definition
| kidney biopsy, fat pad, rectal or gingival biopsy |
|
|
Term
|
Definition
|
|
Term
| Which nephrotic syndrome usually follows URT infection? |
|
Definition
|
|
Term
| What are the 3 ANCA associated illnesses? |
|
Definition
| Wegner's, polyangitis, Churg-Strauss |
|
|
