Term
| What are germline mutations? |
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Definition
| Inherited mutations carried in the DNA of reproductive cells that are present in ALL cells of the body's offspring. |
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Term
| What are the features of malignant tumors? |
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Definition
| Grow fast, divide quickly, don't look like the tissue they come from, invade local tissue, metastasize, have NO capsule. |
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Term
| What are the features of benign tumors? |
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Definition
| Grow more slowly, encapsulated, retain the appearance of local tissue, don't invade local tissue, don't metastasize, don't divide quickly. |
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Term
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Definition
| Oncogenes are mutated protooncogenes that code for protiens that induce protein production normally but when Oncogenes they cause cancerous growth. |
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Term
| What are Care taker Genes? |
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Definition
| Genes that REPAIR or cause cell death in defective cells w/ cellular DNA that has been damaged by UV rays or transcriptional errors. |
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Term
| What are the genes called that put the breaks on protein synthesis in normal people? |
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Definition
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Term
| What are some familial cancer syndromes caused by malfunction of Tumor Supressor Genes? |
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Definition
BRAC1-Breast cancer
Retinoblastoma Rb
Neurofibromatosis Neurofibromatoma |
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Term
| What cytokines accelerate tumor growth? |
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Definition
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Term
| What cytokines suppress tumor growth? |
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Definition
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Term
| Are Tumor suppressor genes recessive or dominant? |
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Definition
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Term
| Are Oncogenes recessive or dominant? |
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Definition
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