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NBDE Flash! - Renal
NBDE Flash! Part 1 Review Series. Home Page: http://www.flashcardmachine.com/p/nbdeflash
17
Dentistry
Professional
02/10/2012

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Cards

Term
What is the macula densa?
Definition
Sodium sensor in part of the distal convoluted distal tubule in the juxtaglomerular apparatus of the kidney
Term
What are JG cells?
Definition
Modified smooth muscle of afferent arteriole in the juxtaglomerular apparatus of the kidney
Term
How is the glomerular basement membrane formed?
Definition
From the fusion of endothelial and podocyte basement membranes.
Term
What is the primary regulatory control of zona glomerulosa secretion?
Definition
Renin-angiotensin
Term
What is the function of the JG cells?
Definition
Secrete renin and erythropoietin
Term
When do the JG cells secrete renin?
Definition
In response to decreased renal BP, decreased sodium delivery to distal tubule, and increased sympathetic tone
Term
Plasma is filtered on the basis of what properties?
Definition
Filtration of plasma occurs according to net charge and size.
Term
What is the glomerular basement membrane responsible for?
Definition
Responsible for the actual filtration of plasma.
Term
What is the glomerular basement membrane coated with? (provides negative charge to filter).
Definition
Negatively charged heparan sulfate (to repell negative charged albumin)
Term
What is not filtered in the glomerulus?
Definition
Albumin due to the size and the negative charged heparan lined membrane.
Term
Where does ADH have its effect
Definition
Collecting Duct
Term
What does ADH cause to be inserted into the collecting duct?
Definition
Aquaporins (Aquaporin II)
Term
What is another name for ADH?
Definition
Vasopressin (Always ask yourself: Is there another name for this term?)
Term
Where is ADH secreted?
Definition
Posterior Pituitary (Neurohypophesis) Made From the Supra Optic Nucleii in the Hypothalmus
Term
What filtrate is totally filtered and neither secreted nor reabsorbed?
Definition
Inulin
Term
para-aminohippurate (PAH)
Definition
Used to measure renal plasma flow
Term
How does ADH influence osmolarity?
Definition
Decreases osmolarity (dilutes plasma)
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