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n2prelude-quiz
random notes
173
Pharmacology
Graduate
09/07/2011

Additional Pharmacology Flashcards

 


 

Cards

Term
onset of formoteral and serevent
Definition
Formoterol (Foradil) is taken 15 minutes prior to exercise and salmeterol (Serevent) is taken 30-60 minutes prior to exercise
Term
which otc pain med should be avoided in moderate asthma patients
Definition
nsaid
Term
what age is zolair indicated for
Definition

12 and older

generic : omalizumab

Term

age indication for 

singular vs zafirlucast

Definition

singular:montelulast: 1 year

zafirlucast: accolate: 5 year

 

Term

zileuton is

indicated for age

monitor?

Definition

zyflo

12 yo or greater

monitor for hepatotox in first three months

Term
dosing singular for asthma
Definition

take in the evening

age 6mos to 5 years take 4mg (granules) 

age 5-14 take 5 mg (chewable)

> 15 10 mg for excercise induce prevention ( 2 hours before excercise)

Term
counseling on singular granules
Definition

4mg

only mix with breast milk and baby formula (in 5ml)

must give within 15 minutes

 

Term
how to take with regards to food for zileuton and zirfirlukast
Definition

zileuton: empty stomach

zirfirlukast: with food

both taken BID

Term
what is the sweetener use in montelukast chewables
Definition
phenylallanine
Term
advair diskus is dose
Definition
1 inhalation BID
Term
wait for how long between short acting asthma doses when taken two puff
Definition
2 minutes
Term
most common side effect of spiriva and ipratopium
Definition
dry mouth
Term

pulmicort respules is 

use mainly in

Definition

budesinide inhalation

use mainly in children

Term

name the dry powder inhalers

how many are there?

Definition

Spiriva,Foradil,Asmanex, Pulmicort Flexhaler, Advair, Flovent Diskus and the Serevent Diskus


Term
what is Dulera
Definition
momethasone+formoterol
Term
what is symbicort
Definition
budesonide + formoterol
Term
what effect does albuterol have on potassium
Definition
hypokalemia
Term
brand name for simvastatin
Definition
zocor
Term
list the drugs that can raise cholesterol
Definition

protease inhibitors, anabolic & corticosteroids (prednisone, etc.), isotretinoin (Accutane), cyclosporine, tacrolimus, beta blockers, thiazide diuretics and phenytoin.

Tbsp-pact ( of fat)

Term

assessing HDL

does it vary by disease state?

low value

high value

Definition

no

< 40 is low

>60 is good

Term
formula for LDL
Definition
TC - (HDL + (TG/5))
Term
brand name for ezetimibe
Definition
Term

which statin is taking with meal

which is taking at bedtime

which can be taken anytime of the day

Definition

lovastatin with meal

fluvastatin and sim at betime

ator and rosu anytime

Term
altoprev
Definition
extended release lovastatin
Term
risk factors for developing CHD
Definition

 (men ≥ 45 y/o; women ≥ 55 y/o),

cigarette smoking,

hypertension (BP >140/90 mmHg, or using antihypertensive medication),

HDL <40 mg/dL,

family history of premature CHD (<55 y/o in 1st degree male relative; <65 y/o in 1st degree female relative).

Term
which niacin has the highest risk of liver damage
Definition
slo niacin (otc)
Term
which niacin is most expensive
Definition
niaspan
Term
which niacin is taken at night with a light snack
Definition
niaspan
Term
which cholesterol meds requires liver monitoring
Definition

niaspan

statin

fenofibrate

Term
lovaza can increase which lipid panel
Definition
LDL
Term
holding cholestyramine solution in mouth may
Definition
cause tooth decay
Term
which fibrabate is the only drug indicated to use with statin
Definition
trillipix
Term

which fibrate is given BID rather than QD

 

Definition
Lopid (gemfibrozil) 30 minutes before breakfast and dinner
Term
which fibrate can induce statin liver tox
Definition
lopid
Term
what is advicor
Definition
lovastatin with niacin
Term
what is lofibra
Definition
fenofibrate
Term

startin ir niacin

vs

er niacin

Definition

Start with ½ of a 500 mg tablet with dinner, can increase weekly up to 3 grams daily (divide the doses and take with meals)


Niacin extended-release (Niaspan) is started at 500 mg QHS x 4 wks (after a light snack), followed by 1000 mg QHS x 4 wks, can increase to 2000 mg QHS. 

Term
tekturna, can they be use in prenancy?
Definition
no
Term
nicardipine sublingual in hypertensive emergency
Definition
do not use due to uncontolled drop in blood pressure
Term
which ethnicity has increase risk for angioadema
Definition
african american
Term
which antihypertensive can cause ginjival hyperplasia
Definition
verapamil
Term
generic for metaglip
Definition
glipizide + metformin
Term
generic for avandaryl
Definition

rosiglitazone

amaryl

Term
generic for junamet
Definition
sitaglipton + metformin
Term
dose for prandin and starlix
Definition
Repaglinide (Prandin) is started at 0.5 mg (if the A1C is less than 8%) or 1-2 mg TID. Nateglinide (Starlix) is dosed 60 mg TID if close to control, or 120 mg TID.
Term
what is opticlik
Definition
lantus insulin
Term
equation for estimation of avarage glucose
Definition
eAG = 28.7 x A1C – 46.7
Term
contraindication in metformin use
Definition
hypoxia (copd,chf)
Term
medguide for Dpp4 inhibitor
Definition
pancreatitis
Term
in drugs that are renally monitored, what should be counseled
Definition
take plenty of water?
Term
what can we counsel about welchol and tg when first use
Definition
initial spike in tg
Term
what is the prefer test for gestational diabetes
Definition
glucose tolerance
Term
acarbose on lipid profile
Definition

deacrease tg

increase hdl

Term
which sulfonururea has long standing hypoglycemia
Definition

glyburide and chorpromide

( not rec in elderly)

Term
signs of severe lactic acidosis
Definition
Weakness, dizziness, fatigue and difficulty breathing
Term
which diabetes drug class require opthamic exam
Definition
tzd
Term
is cefalexin use to treat uti?
Definition

yes

250 QID

Term
bactrim regards to food?
Definition
empty stomach
Term
isoniazid in regards to food
Definition
take on an empty stomach
Term
storage of isoniazid store in 
Definition
room temperature
Term

ratio for fluconazole 

oral to iv

Definition
1:1
Term
peak of trough to trobramycin
Definition

peak 5-10

trough 2

Term

what is avelox

moa

Definition

moxifloxacin

topoisomerase inhibitor

Term
class of linezolid
Definition

oxazolidinone

a weak maoi inhibitor

Term

tigecyline is 

derivative of 

Definition

tigacil

derivative of minocycline

Term
side effect of cyclovir
Definition
head ache and nausea
Term

candida crusei

which antifungal cover and which doesnt

 

Definition

vonriconazole cover

fluconazole does not cover

Term

dosing amioglycoside

extended interval dosing aka

Definition

xtended Interval (formerly known as “Once Daily Dosing”) for gentamicin and tobramycin is 4-7 mg/kg/day. The dose given in the question (15 mg/kg/day) is used for once-daily dosing of amikacin. Extended-interval dosing can help preserve renal function (the primary toxicity) and is more cost-effective than administering the medication via conventional dosing.

Term
does penicillin need dose reduction
Definition
no
Term
nitrofurantoin
Definition

creatinine clearance, stop <60

take with food to increase absortion

Term
micafungin
Definition

enchinocandin 

only avail iv

infuse over 1 hour

has histamine related symptoms

Term
why prefer tigacycline over telithromycin
Definition
qt prolongation
Term
voriconazole in regards to meal
Definition
i houre before and 1 hour after
Term
solodyn is 
Definition
minocycline
Term
coumadin
Definition

2.5,7.5,10,1,2,3,4,5,6

(please let greg tan bring peaches to your wedding)

Term

rifaxamin 

bacterial or protozoa

use to treat

Definition

bacterial

travelers diarrhea

Term
days of therapy for vaginal fungal
Definition

7 days

clotrimazole

miconazole

Term
pyrazinamide is contraindicated in
Definition

acute gout

hepatic dysfunction

Term
faecium drugs
Definition

daptomycin

synercid

Term
trichomonas drugs
Definition

Metronidazole 2 grams po x 1

Tinidazole 2 grams po x 1

Term
pepto bismo
Definition
 



 
Term
tx for lyme in prenancy
Definition

thir gen ceft 

amox

Term

levofloxacin

regards to food

Definition

oral: doesnt matter

solution: empty stomach

Term
what is mycelex
Definition
clotrimozole troche
Term

non hiv treatment for oral candidiasis

mod to severe

mild

Definition

fluconazole; moderate to severe

mild: mycelex

oral: 7-14 days

esophageal: 14-21 days

Term
administration of itraconazole
Definition

oral solution on empty stomach

oral capsule after meal

Term
teflaro is 
Definition

ceftaroline

treat MRSA

Term

bicillin cr

vs 

bicillin LA

 

Definition

CR: benzathine+ prcaine

LA: benzathine

Term
psuedomonas coverage
Definition

all carbopenems except erta

cipro and

cefepime

Term

moxatag

admin?

formulation?

creatinine clearance?

Definition

withing 1 hours of finishing a meal

extended release

do not use in crcl < 30

Term
iv metronidazole should be kept in 
Definition
room temp to reduce crystals
Term
cipro suspension administration
Definition

should not admin through tube feed

hold tube feed for 1 hours before and two hour after

 

Term
does tygacil cover VRE
Definition
no
Term

ketek is

monitor 

Definition

telithromycin

liver and kidney

Term

rifampin

food or no food?

 

 

Definition
empty stomach
Term

ethambutal

side effect

 

Definition
optic neuritis
Term
which cephalosporins covers psuedomonas
Definition

ceftazidime-fortaz

cefepime-maxipime

Term

macrolide comparason

which increase INR

which increat qt

Definition

all increase qt

clarith and erythin increase inr

Term
heparin can be given via
Definition

iv

subQ

Term
normal aptt level is 
Definition

22-39

heparin therapeutic level is 60-85

Term
advantage of lmwh over heparin
Definition

no monitor

cost effective

more consistent

Term
long term complication of heparin
Definition

hyperkalemia

alopecia

osteoporosis

Term
orthopedic surgery should be on warfarin for how long?
Definition
3 months
Term
pradaxa moa
Definition
oral DTI
Term
lovenox dose in renal <30
Definition
30 mg qd
Term
when inr is between 5 and 9 the options are
Definition


 
Term
when inr is >9
Definition

vitamin k 2.5-5

in severe bleeding do 10mg

Term
blackbox for LMWH
Definition
spinal/epidural hematoma formation
Term
food that are high in vitamin K
Definition

canola and soybean oil

green and black tea

cauliflower

chick peas

endive

cabbage

 

Term
counseling point on pradaxa
Definition
swallow whole
Term
does pradaxa requires monitoring
Definition
no
Term
renal dosing of pradaxa
Definition

crcl 15-30 75mg bid

if not th: 150 BID

Term
how to switch warfarin to dabigatron
Definition
dc warfarin and start dabi when INR is below 2
Term
risk factor for VTE
Definition

age greater than 60

previous history of DVT or PE

acute infection

nephrotic syndrome

body mass index greater than 24

Term
should you provide aspirin to VTE patients?
Definition
NO, especially elderly
Term
inpatient who are at risk of bleeding use
Definition
stock device
Term
what hyperkalemia do to dig
Definition
increase it
Term
which loop has the great risk of ototox
Definition

edecrin

iv formulation

Term
which ra drug is safe to use in hf 
Definition
methotrexate
Term
fenfluramine
Definition

pondimin

diet drug

Term
dexfenfluramine
Definition

redux

diet drug

Term
fen-fen
Definition

combo of 

fenfluramine and dexfenfluramine

Term

fen-fen 

cause what kind of cardiovascular issue

Definition
heart valve disease
Term
know hf staging
Definition
Term
diruretics may
Definition

increase lipid

increase blood glucose

Term
what kind of ca blockter to avoid in hf
Definition

diltiazem

verapamil

Term
moa of dig
Definition

increase contraction 

decrease heart rate

Term
metopralol comes in as
Definition

tablet

can be scored

Term
how to dose carvedilol
Definition

<85 kg

25 BID

>25

50 BID

cr can go 10,20,40,80 over interval of at least two weeks

Term
which hf drug does not reduce mortality
Definition
digoxin
Term
digoxin is metabolized by
Definition
hepatic
Term
symptoms of sle
Definition

fever

join/muslce aches

fatique

Term
uncontroll glucose for years may cuase what type of pain
Definition

neuropathic pain

fibromyalgia

Term
what is nabumatone
Definition

relafen

nsaid

Term
what kind of allergy does zonisamide cause
Definition
sulfur allergy
Term
special side effect of inmethacin
Definition
pyschiatric
Term
which pain med have serotonic property
Definition

meperidine

tramadol

Term
tylenol 3 side effect
Definition

nausea

constipation

Term
ibuprofen last longer than acetamenophen
Definition
Term
opana ir and er in regards to food
Definition
take on empty stomach
Term

divalporex sodium is 

valproic acid or valproate is

black box

Definition

depakote ER

depakene

hepatic

prancreatitis

teratogenicity

Term
side effect for divalproex
Definition

gi

alopeicia

sedation

weight gain

Term
anticonvulsants that is associated with weight loss?
Definition

lamotrigine

levetiracetam

topiramate

zonisamide

Term
anticonvulsant taht are indicated for migrain prophylaxis
Definition

topamax

depakote

Term
can valproate cuase rash
Definition
yes
Term
side effect of levetiracetam
Definition

somnolence 

hostility

norvousness 

asthenia

Term
side effect of oxcarbazepam
Definition

sleepiness

ataxia

diplopia

Term
side effect of carbamazepine
Definition

nausea

drowsiness

dizziness

supplement vit d and folate

siadh

Term
agents use for absence seizure
Definition

ehtosuximide

valproate

lamotrigine

topiramate

Term
how to adjust phenytoin level
Definition

pht measured/ (.2xalbumin)+.1)

level 10-20

Term
iron content
Definition

ferrous fumarate 33%

ferrous sulfate 20

 

Term

poly vi sol 

fer in sol

Definition

are infant vitamin drops with iron and vit d

fer in sol (iron only for infant)

Term
treatment of iron pill usually last 
Definition
3-6 months
Term
chillings test is use to confirm
Definition
vitamin b12 deficiency
Term

iv iron cuase

heper or hypotension

Definition
hypo
Term
epogen and procrit given via
Definition
subQ
Term

rheumatoid arthritis

clinical condition

Definition

both sides

 

Term
dmard should be starting withing how many months of diagnosis
Definition
3
Term

tNF blocking agent 

check for 

Definition

etanercept

white blood celll

tb

liver enzymes

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