Term
| most common species in candidiasis: |
|
Definition
|
|
Term
| who is most at risk for candidiasis? |
|
Definition
|
|
Term
| clinical manifestations of cutaneous candidiasis: |
|
Definition
| generalized puritus erythematous rash w distinct borders around folds, axilla, hands & feet |
|
|
Term
| 4 locations for mucocutaneous candidiasis: |
|
Definition
1. oropharyngeal
2. denture stomatitis
3. esophagitis
4. vulvovaginitis |
|
|
Term
|
Definition
1. several days of FEVER
2. inresponsive to Abx
3. macronodular skin lesions
4. eye/retinal lesions
5. septic shock |
|
|
Term
| Candidiasis work up: 6 points |
|
Definition
1. KOH prep
2. Blood cultures
3. UA
4. Serum beta D glucan detection assay
5. endoscopy w/ or wo Bx
6. opthalmic exam if seriously ill |
|
|
Term
| Candidiasis: endocarditis Tx: |
|
Definition
|
|
Term
| which antifungal is mostly used for candidiasis? |
|
Definition
|
|
Term
|
Definition
1. clotrimazole
2. Nystatin (mouth wash)
3. fluconazole
4. amphoteracin B |
|
|
Term
| if left untreated candidemia can lead to: |
|
Definition
| metastatic infection of the eyes, vertebral collumn, liver & spleen |
|
|
Term
| transmission of cryptococcosis: |
|
Definition
|
|
Term
| what is the major pathogenic species of cryptococcosis? |
|
Definition
| C. neoformans (serotype D) |
|
|
Term
| cryptococcus responsible for human infections: sexual or asexual form |
|
Definition
|
|
Term
| what is the microscopic test for cryptococcus? |
|
Definition
| india ink looking for capsule in CSF |
|
|
Term
| major cryptococcus source: |
|
Definition
|
|
Term
| which patient population accounts for 50% of cryptococcus infections? |
|
Definition
|
|
Term
| what is the most virulent strain of cryptococcus and where is it found? |
|
Definition
| Cryptococcus var gatii Africa, india, SE Asia, Astralia, Central/South AMerica |
|
|
Term
| sign assoc with cryptococcus var gatii: |
|
Definition
| large mass lesions (cryptococcomas) |
|
|
Term
| cryptococcus shows a preference for: |
|
Definition
|
|
Term
| clinical manefestation of pulmonary cryptococcus pneumonia: |
|
Definition
| asymptomatic self limiting dz in healthy. chronic lung dz - may disseminate to the CNS |
|
|
Term
|
Definition
| Amphotericin B for 2wks then Flucytosine for 10wks (for life in AIDS) |
|
|
Term
| what is the most problematic cause of cryptococcus in CSF? |
|
Definition
| increased intracranial pressure must take off prn |
|
|
Term
| most pneumocystis infections occur in which patient population? |
|
Definition
| those that are unaware they have HIV since HIV patients take prophylaxis |
|
|
Term
| what is the CD4 count have to be for pneumocystis infection? |
|
Definition
|
|
Term
| where is the pneumocystis infection normally? |
|
Definition
|
|
Term
|
Definition
1. blood test
2. radiographs
3. hypoxia
4. LDH >500
5. CXR
6. Chest CT
7. Gallium scan |
|
|
Term
| which test has a 99% sensativity for pneumocystis? |
|
Definition
| bronchoscopy & transbronchial Bx |
|
|
Term
|
Definition
| trimethoprim-sullfamethoxazole |
|
|
Term
| what is the risk in the Tx for pneumocyctis in AIDS pts? |
|
Definition
| 20-80% of AIDS pts have adverse reaction (SJS) |
|
|
