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MWU Pharmacology test 3
pharm cards test 3
12
Pharmacology
Professional
10/17/2012

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Cards

Term
Phenobarbital
Definition
stimulate GABA receptor.
not 1st-line due to side effects.
Term
Phenytoin (Dilantin)
Definition
blocks voltage-gated Na+ channels. concentration increases disproportionately with dose.
drug interacions, SJS!
Term
Carbamazepine (Tegretol)
Definition
blocks voltage-gated Na+ channels
Term
Ethosuximide
Definition
blocks T-type Ca+ channels.
Only absence seizures.
Term
Valproic acid (Depakote)
Definition
blocks voltage-gated Na+ channels
AND blocks T-type Ca+ channels
Term
Fosphenytoin
Definition
IV pro-drug of phenytoin for Status Ep
Term
Gabapentin (Neurontin)
Definition
for partial seizures and neuropathic pain. not metabolized
Term
Oxcarbazepine
Definition
blocks voltage-gated Na+ channels. Only partial seizures.
Term
Lamotrigine (Lamictal)
Definition
inhibit voltage-gated Na+ channels. Ca+ channels too.
Term
Topiramate (Topomax)
Definition
inhibit voltage-gated Na+ channels. stimulate GABA.
Term
Levetiracetam (Keppra)
Definition
mostly adjunctive.
rapid titration, high safety.
Term
Status Epilipticus
Definition
lorazepam, fosphenytoin
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