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Musculoskeletal
PANCE review
143
Health Care
Graduate
08/08/2011

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Term
most common arthropathy among adults
Definition
OA
Term
common sites of OA involvement
Definition
DIP (Herberden's nodes)
PIP (Bouchard's nodes)
wrist
hip
knee
spine
Term
what joint is usually spared in OA? (3)
Definition
MCP
ankle
elbow
Term
tx of OA
Definition
weight reduction
moderal physical activity
acetominophen
NSAID
intra-articular steroids
Term
RA diagnostic criteria
Definition
morning stiffness > 1hr for atleast 6wks
arthritis and soft tissue swelling of > 3 joints for > 6 wks
arthritis of the hand joints > 6 wks
symmetric arthritis > 6 wks
subcutaneous nodules over extensor surfaces, bony prominances, or juxta-articular regions
Rheumatoid factor at or above 95th percentile
radiologic changes suggestive of joint erosion or body decalcification
Term
what joint is often spared with RA?
Definition
DIP
Term
extra-articular manifestations of RA
Definition
changes in the skin, lungs, kidneys, eyes, liver, blood system, and heart
Term
antibodies that are frequently positive with RA?
Definition
rheumatoid factor
anti-CCP antibodies
Term
tx of RA
Definition
consult with a rheumatologist
occupational and physical therapy
NSAIDs + DMARD (methotrexate)
Term
septic joint analysis WBC count
Definition
> 50,000
Term
rash illicited by scratching the skin in susceptible areas
Definition
Koebner's phenomenon
Term
spiking fevers, myalgias, polyarthralgia and a typical salmon pink maculopapular rash appaering in the evening and with the fever
Definition
Still's disease
Term
JRA with involvement of four or fewer medium to large joints
Definition
pauciarticular
Term
in JRA a + ANA test indicates a tendency for what?
Definition
uveitis
Term
MC pathogen in joint infections
Definition
staph aureus
Term
tx of septic arthritis
Definition
agressive IV abx followed by 7-10 days of oral abx
Term
inflammatory arthritis wiht skin involvement usually preceding joint disease by months to years
Definition
psoriatic arthritis
Term
common feature of psoriatic arthritis seen in the fingers
Definition
sausage like appearance caused by arthritis and tenosynovitis
Term
of the pencil in cup deformity of the proximal phalenx
Definition
psoriatic arthritis
Term
seronegative arthritis that presents with a tetrad of urethritis, conjunctivitis, oligoarthritis, and mucosal ulcers
Definition
reactive arthritis (Reiter's Syndrome)
Term
leading cause of nontraumatic monoarthritis
Definition
Reiter Syndrome
Term
initial attack of metatarsal phlangeal joint of the great toe (podogra)
Definition
gout
Term
joint analysis of gout shows
Definition
needle shaped, negatively birefringent (yellow) urate crystals
Term
tx of gout
Definition
NSAIDs (indomethacin)
Term
management of gout between acute attacks
Definition
colchicine, probenecid, sulfapyrazone, allopurinol, febuxostat
Term
tx of gout with kidney disease
Definition
febuxostat
Term
intra-articular deposition of calcium pyrophosphate
Definition
pseudogout
Term
joints most commonly involved in pseudogout
Definition
knee
wrist
elbow
Term
joint analysis of pseudogout shows
Definition
rhomboid shaped calcium pyrophosphate crystals. positively birefringent (blue)
Term
SLE is most common in
Definition
women of childbearing age
Term
dx criteria for SLE
Definition
malar rash
discoid rash
photosensitivity
oral ulcers
arthritis
serositis
renal disease
ANA
hematologic disorders
immunologic disorders
neurologic disorders
Term
inflammatory disease of striated muscle affecting the proximal limbs, neck, and pharynx
Definition
polymyositis
Term
tx of polymyositis
Definition
high dose steroids, methotrexate, or azathioprene
Term
pain and stiffness n the neck, shoulder, and pelvic girdle and is accompanied by constitutional sxs (fever, fatigue, weight loss, depression)
Definition
polymyalgia rheumatica
Term
tx of PMR
Definition
low dose corticosteroid therapy
Term
small and medium artery inflammation involving the skin, kidney, peripheral nerves, muscle, and gut
Definition
polyarteritis nodosa
Term
skin lesions associated with polyarteritis nodosa
Definition
palpable purpura
livedo reticularis
Term
diagnostic test for polyarteritis nodosa
Definition
vessel biopsy or angiography
Term
antibody suggestive of polyarteritis nodosa
Definition
ANCA
Term
tx of polyarteritis nodosa
Definition
high dose corticosteroids
cytotoxic drugs and immunotherapy may also be used
Term
disease characterized by depostion of collagen in the skin, and less commonly the kidney, heart, lungs, and stomach
Definition
scleroderma
Term
vasospasm of the digital arteries
Definition
Raynaud's phenomenon
Term
antibody associated with limited scleroderma
Definition
anticentromere antibody
Term
components of CREST syndrome
Definition
Calcinosis
Raynaud's phenomenon
Esophageal dysfunction
Sclerodactyly
Telangiectasias
Term
autoimmune disorder that destroys the salivary and lacrimal glands
Definition
Sjogren's syndrome
Term
xerostomia
Definition
dry mouth
Term
xeophthalmia
Definition
dry eyes
Term
characteristic features of Sjogren's syndrome
Definition
xerostomia
xerophthalmia
keratoconjunctivitis
Term
diagnostic test for Sjogren's syndrome
Definition
Schirmer's test with wetting of less than 5mm of filter paper placed over the lower eyelid for 5 minutes
Term
medication that can be used to increase saliva flow
Definition
pilocarpine
Term
tx of fibro
Definition
SSRI, SSNRI, TCA
pregabalin = only FDA approved drug
Term
inflammation of the tendon
Definition
tendinitis
Term
inflammation of the enclosed tendon sheath
Definition
tenosynovitis
Term
inflammatory disorder of the bursa (think walled sac lined with synovial tissue)
Definition
bursitis
Term
housemaid's knee
Definition
suprapatellar bursitis
Term
inflammation of the bone caused by a pyogenic organism
Definition
osteomyelitis
Term
MC organism in osteomyelitis
Definition
Staph Aureus
Term
acute hematogenous osteomyelitis most commonly affects who? where?
Definition
children in the long bones
Term
exogenous osteomyelitis results from what?
Definition
open fracture or surgery
Term
pts with sickle cell are at increased risk for osteomyelitis from what?
Definition
salmonella
Term
tx of acute vs chronic osteomyelitis
Definition
acute = abx x 3 wks
chronic = abx x 4wks - 24 months
Term
most common primary carcinomas that mets to the bone (5)
Definition
prostate, breast, lung, kidney, thyroid
Term
MC site of bony mets
Definition
spine
Term
MC primary benign bone neoplasm of the hand
Definition
enchondroma
Term
common benign soft tissue masses (2)
Definition
lipomas
ganglion
Term
MC primary sarcomas of bone (3)
Definition
chondrosarcoma
Ewing's sarcoma
osteosarcoma
Term
MC primary malignant bone tumor
Definition
multiple myeloma
Term
night pain is often associated with
Definition
malignancy
Term
a painful mass attached to the bone is likely to be
Definition
malignant
Term
what two serum markers are elevated when bone is broken down and remodeled?
Definition
alkaline phosphatase
lactate dehydrogenase
Term
disease of abnormal bone remodeling, characterized by decreased total boen volume, and increased susceptibility to fractures
Definition
osteoperosis
Term
MC fracture sites in osteoperosis
Definition
vertebrae
hip
distal radius
Term
what type of bone is primarily affected by Type 1 osteoperosis
Definition
trabecular
Term
who is at high risk for type 2 osteoperosis? what bone does it affect?
Definition
high risk = pts > 75 to with poor calcium absorption
affects trabecular and cortical bone
Term
tx of osteoperosis
Definition
weight bearing exercise
adequate calcium, vit D, and phosphorus
smoking cessation
limited alcohol intake
Term
fx of the head of the 5th metacarpal
Definition
Boxer's fx
Term
what kind of xrays should you get to evaluate a fx?
Definition
2 views 90 degrees apart
Term
tx of Boxer Fx
Definition
ulnar gutter split or cast - with fingers in 90 degrees of flexion
Term
fx of the distal radius with volar displacement
Definition
Smith fx
Term
fx of the distal radius with dorsal displacement
Definition
colles fx
Term
fx of the distal 1/3 of radius with disruption of the DRUJ
Definition
Galeazzi fx
Term
fx of the proximal 1/3 of the ulna with dislocation of the radial head
Definition
Monteggia fx
Term
used to identify malingering
Definition
Waddell's sign
Term
red flags with low back pain
Definition
TUNA FISH
trauma
unexplained weight loss
neuro sxs
age > 50 yo
fever, malaise
IV drug use
steroids
hx of cancer
Term
how do you confirm HNP?
Definition
MRI
Term
w is spondylolithesis graded?
Definition
Meyreding's scale
0 = 0%
1 = < 25%
2 = 25-50%
3 = 51-75%
4 = 76-99%
5 = complete
Term
sign of spondylolisthesis on xray
Definition
scotty dog with broken neck
Term
back pain with sitting, decreased with flexion
Definition
spinal stenosis
Term
special tests for thoracic outlet syndrome (3)
Definition
adson test
roos test
halstead test
Term
complication of humeral fx
Definition
NV compromise
radial nerve, brachial artery
Term
medial epicondylitis is compression of what nerve?
Definition
ulnar
Term
risk factors for carpal tunnel
Definition
repetitive hand work
thyroid disorders
pregnancy
trauma
alcoholism
DM
gout
Term
paresthesia with thenar atrophy
Definition
carpal tunnel
Term
tx of carpal tunnel
Definition
cock up wrist splint
Term
is hemarthrosis more common with crutiate ligament tear or collateral ligament tear?
Definition
cruciate ligament
Term
+ lachmans and anterior drawer
Definition
ACL tear
Term
ACL, PCL, and collateral ligament tear
Definition
knee dislocation
Term
Mc ligament injury in the knee
Definition
MCL
Term
MCL prevents what stress?
LCL prevents what stress?
Definition
MCL = valgus
LCL = varus
Term
are medial or lateral meniscus injruies more common?
Definition
medial
Term
LCL injury is associated with what nerve injury?
Definition
peroneal
Term
special tests used for meniscus injuries
Definition
McMurray's, Appley's
Term
where are meniscal cysts more common?
Definition
lateral joint
Term
tibial plateau fractures are classified how?
Definition
Schatzker classfication
Term
what radiographs should you get for tibial plateau fx?
Definition
CT with scout views
Term
what radiographs for patellar fx?
Definition
xray
AP, Lateral, Sunrise view
Term
complication of tibiofemoral dislocation
Definition
pulselessness = EMERGENCY!
Term
inability to extend leg could be?
Definition
patellar tendon rupture
Term
anterior knee pain with stair climbing or prolonged sitting
Definition
patellofemoral syndrome (chondromalacia)
Term
special test for chondromalacia
Definition
apprehension test
Term
WBC counts for knee effusion
Definition
normal = < 300
inflammatory = 2-80 thousand
septic = > 80 thousand
Term
MC ankle injury
Definition
inversion
Term
what are ottowa rules used for?
Definition
decide when to xray an ankle sprain
Term
grades of ankle sprain
Definition
1 = partial tear of ant. talofibular ligament
2 = partial-complete tear of ant. talofibular ligament and partial tear of calcaneofibular ligament
3 = complete rupture of ant. talofibular ligament and calcaneofibular ligament
Term
what is Thompson test?
Definition
special test for Achilles Tendon Rupture
pt lying prone - squeeze on calf - no movement of foot
Term
"walking on a stone"
Definition
heel spur
Term
pain in the morning with first step
Definition
plantar fasciitis
Term
ecchymosis and heel widening from fall or jump
Definition
calcaneous fx - get mortise and harris views
Term
pain between 3rd and 4th metatarsal head - severe burning pain increased with activity
Definition
Morton's neuroma
Term
what is Morton's test?
Definition
squeeze around the metatarsal heads = pain
Term
metatarsals displaced from tarsals
Definition
lis frank fx
Term
dislocation of mid-tarsal (talonavicular and calcaneocuboid) joints of the foot
Definition
Chopart's foot
Term
oblique, comminuted fx of distal tibia that extends through the tibiotalar articular surface
Definition
Pilon fx
Term
pain and tenderness over head of 5th metatarsal
Definition
Jone's fx
Term
tx of toe fx
Definition
buddy tape with stiff sole shoes
Term
neurogenic arthropathy - bag of bones
Definition
Charcot's foot
Term
DISH
Definition
diffuse idiopathic skeletal hyperostosis - ossification of longitudinal ligaments of the spine - looks like candle wax dripping down spine
Term
key player in RA
Definition
tumor necrosis factor (TNF)
Term
primary target of RA
Definition
synovium
Term
swan neck and boutoniere deformity, Baker's cyst, hammertoe, splaying of the forefoot
Definition
RA
Term
Lissamine Green (less painful) and Rose Bangal tests are used for
Definition
Sjorgren's syndrome
Term
URI + pulmonary + renal involvement
C-ANCA
Definition
Wegener's
Term
type of lupus mostly contained to skin (face, scalp, arms, upper chest) - tends to scar
Definition
discoid
Term
lupus associated with annular, circular, or papulosquamous lesions, sun exposed areas.
SSA (ro) and SSB (la) antbodies
Definition
SCLE
Term
how long do neonatal lupus sxs last?
Definition
about 8 months
Term
antibody associated with lupus nephritis
Definition
anti-ds DNA
Term
5 types of GN
Definition
minimal change - good prognosis
mesangial - interstitium
focal proliferative - spotty glomeruli
membranous - heavy proteinuria
diffuse proliferative - aggressive
Term
what is usually spared in PAN
Definition
lungs
Term
what is associated with PAN?
Definition
Hep B, C and HIV
Term
symmetrical proximal muscle weakness
Definition
myositis
Term
anti-centromere antibody
Definition
CREST
Term
SCL 70 antibody
Definition
PSS
Term
who should get a bone mineral density test?
Definition
women 65+
women 70+
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