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Muscle Tissue
N/A
22
Histology
Undergraduate 4
05/08/2012

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Cards

Term
fibril
Definition
spontaneously assembled from collagen subtypes I-IV - fibrilogenesis; 4-fold staggered overlap; form thick, eosinophilic FIBERS
Term
muscle striations by LM
Definition
alternating I (light) and A (dark) bands
Term
white muscle fibers
Definition
fast twitch, glycolytic, fatigueable
Term
red muscle fibers
Definition
slow twitch; oxidative; repetitive
Term
myoglobin
Definition
O2-binding protein; closely resembles hemoglobin; varying amounts in muscle fibers
Term
epimysium
Definition
dense CT; surrounds collection of fascicles
Term
fascicle
Definition
functional units of muscle fibers that tend to work together to perform a specific function; surrounded by perimysium
Term
perimysium
Definition
thicker CT; surrounds group of fibers; forms bundle or fascicle
Term
endomysium
Definition
reticular fibers that surround individual muscle fibers; small-diameter blood vessels; neuronal branches (very fine) fun parallel
Term
sarcolemma
Definition
muscle fiber plasma membrane and endomysium
Term
visceral striated muscle
Definition
morphologically identical to skeletal muscle; soft tissues: tongue, pharynx, diaphragm, esophagus
Term
thick filaments
Definition
myofilament; primarily myosin II; about 15 nm diameter
Term
thin filaments
Definition
myofilament; primarily actin; 6-8 nm diameter
Term
alpha-actinin
Definition
tethers thin filaments from adjacent sarcomeres to common Z-line
Term
titin
Definition
stretchable ("elastic") protein linking thick filament to Z-line; largest known protein
Term
H-band
Definition
light, central region of dark A-band; ONLY myosin
Term
M-line
Definition
middle line of H band; each myosin joined laterally to its myosin neighbor
Term
I-band
Definition
isotropic; DOESN'T bend polarized light - appears bright only thin actin filaments; width DECREASES during contraction
Term
Z-line
Definition
Z = "between"; middle line of I band contains actin-binding proteins (alpha-actinin) which link actin of consecutive sarcomeres; demarcates sarcomeres
Term
myoblasts
Definition
fuse during development to form multinucleated syncytia - muscle fibers
Term
toponin
Definition
one complex binds to one tropomyosin which binds to actin
TnT = binds tropomyosin
TnC = finds Ca2+ to initiate contraction
TnI = binds actin and inhibits actin-myosin interaction
Term
dystrophin
Definition
links actin of sarcomeres to laminin in external lamina; largest known gene
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