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Muscle tissue and physiology
Muscle tissue and Physiology
37
Biology
Undergraduate 1
11/14/2011

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Term
Skeletal Muscle Tissue (location, striated or not, voluntary or involuntary)
Definition
Attached to Bones and Skin
striated
Voluntary
Term
Cardiac Muscle Tissue (location, striated or not, voluntary or involuntary
Definition
Only in heart
striated
involuntary
Term
Smooth Muscle Tissue (location, striated or not, voluntary or involuntary)
Definition
walls of hollow organs (stomach, bladder)
not striated
invlountary
Term
Four Muscle Functions
Definition
1) Movement of bones or fluids
2) maintaining posture and body position
3) stabilizing joints
4) heat generation
Term
3 connective tissue sheaths
Definition
1) epimysium
2) Perimysium
3) Endomysium
Term
Epimysium (location)
Definition
Surrounds entire muscle
Term
Perimysium (location)
Definition
surround fascicles (groups of muscle fibers)
Term
Endomysium (location)
Definition
surrounding each muscle fiber
Term
2 types of muscle attachment
Definition
Directly
indirectly
Term
myofibrils
Definition
Densely packed, rodlike elements
80% of cell volume
exhibit striations: perfectly aligned repeating dark A bands and light I bands
Term
Sarcomere
Definition
smallest unit of muscle fiber
region of myofibril between two Z discs
Term
Thick Filaments
Definition
run entire length of A band
tails: 2 interwoven heavy polypeptide chains
Heads: 2 smaller light polypeptide chains that act as cross bridges, binding sites for thin filaments, binding site for ATP, ATPase enzymes
Term
Thin Filaments
Definition
run entire length of I band and partway into A band
Twisted double stand of fibrous protein F actin
Term
Z discs
Definition
coin-shaped sheet of proteins that anchor thin filaments and connect myofibrils to one another
Term
H zone
Definition
lighter midregion where filaments do not overlap
Term
M line
Definition
line of protein myomesin that holds adjacent thick filaments together
Term
Sarcoplasmic Reticulum
Definition
network of smooth endoplasmic reticulum surrounding each myofibril
Term
T tubules
Definition
continuous with sarcolemma
penetrates the cells interior at each A band-I band junction
Term
Triad
Definition
where T tubule has terminal cisternae of SR on each side
Term
Muscle Contraction
Definition
generation of force
Term
requirements for muscle contraction
Definition
1) Activation: neural stimulation at a neuromuscular junction
2) excitation-contraction coupling (EC coupling): generation and propagation of an action potential along the sarcolema, final trigger: a brief rise in intracellular CA2+ levels
Term
neuromuscular junction
Definition
situated midway along the length of a muscle fiber.
Term
Synaptic cleft
Definition
gel filled space between axon terminal and muscle fiber
Term
what is released by the axon terminal synaptic vesicles?
Definition
Acetylcholine (ACh)
Term
Events of neuromuscular junction
Definition
nerve impulses arrive at axon terminal,
ACh is released and binds with receptors on the sarcolemma
electrical events lead to the generation of an action potential
Term
Destruction of Acetylcholine (ACh)
Definition
ACh effects are quickly terminated by the enzyme acetylcholinesterase
Term
EC coupling (Excitation-Contraction)
Definition
sequence of events by which transmission of an AP along the sarcolemma leads to sliding of the myofilaments.
Term
Latent period
Definition
time when E-C coupling events occur
time between AP initiation and the beginning of contraction!
AP is propagated along sarcolemma T tubules
Term
Motor unit
Definition
a motor neuron and all muscle fibers it supplies
Term
Isotonic Contraction
Definition
muscle changes in length and moves the load
Term
Isometric contraction
Definition
the load is greater then the tension the muscle is able to develop
the muscle neither shortens or lengthens
Term
How is ATP regenerated (3 ways)
Definition
1) Direct phosphorylation of ADP by creatine phosphate
2) Anaerobic pathway (glycosis)
3) aerobic respiration
Term
Anaerobic pathway
Definition
glucose created 2 ATP
no oxygen used
Term
Aerobic pathway
Definition
Glucose used to create 32 ATP
Oxygen is used
Term
Velocity and Duration of contraction influenced by?
Definition
1) muscle fiber type
2) load
3) recruitment
Term
two characteristics of muscle fiber type
Definition
1)speed of contraction
2) metabolic pathway for ATP synthesis
Term
Three types of muscle fibers
Definition
slow oxidative fibers- aerobic
fast oxidative fibers- anaerobic
fast glycolitic fibets anaerobic
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