Term
****
Remember that Muscarinic receptors are ACh receptors
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Definition
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Term
| What are the actions of Atropine? |
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Definition
**Remember that Atropine is a muscarnic antagonist
EYE = increase pupil dilation, cytoplegia (paralysis of ciliary mm in the eye, leads to loss of accomodation)
AIRWAY = decrease secretions
Stomach = decrease acid secretion
Gut = decrease gut motility
Bladder = decrease urgency in cystitis |
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Term
| You have a px with diarrhea, urination, miosis, bronchospasm, bradycardia, excitation, lacrimation, sweating, and salivation. what drug do you give them? |
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Definition
The px is suffering from cholinesterase inhibitor poisoning (organophosphates)
Give them Atropine, a muscarinic antagonist that will block receptor activation |
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Term
| What are the side effects of Atropine toxicity? |
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Definition
-increase body temperature (due to decreased sweating)
-dry, flushed skin
-cycloplegia (paralysis of ciliary mm, leading to loss of accomodation)
-disorentation/delerium
-increased heart rate
-dry mouth |
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Term
Benztropine
-organ system
-applications |
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Definition
Benztropine has CNS effects
-It is used to treat Parkinsons |
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Term
| What is Benztropine used to treat? |
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Definition
parkinson's
Remember that it is a Muscarinic antagonist |
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Term
Scopolamine?
Organ system
Application |
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Definition
Scopolamine has CNS effects
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Term
Ipratropium
Organ system
Application |
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Definition
affects resiratory system
used to treat COPD and asthma
"I pray I can breathe soon |
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Term
Oxybutynin
Organ system
Application |
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Definition
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Term
Darifenacin
Organ system
Application |
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Definition
Genitourinary
Reduce bladder spasm |
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Term
Solifenacin
Organ system
Application |
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Definition
Genitourinary
Reduce bladder spasm |
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Term
| What 3 muscarinic antagonists affect the genitourinary ssytem and are used to reduce bladder spasm? |
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Definition
Oxybutynin
Darifenacin
Solifenacin |
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Term
Glycopyrrolate
Organ system
Application |
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Definition
Affects the GI and REspiratory systems
parenteral = preop use to reduce airway secretions
oral = reduce redrooling, treat peptic ulcer
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Term
The use of Glycopyrrolate depends on how it is administered.
what is the use for
parenteral administration
oral administration |
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Definition
parenteral = preop use to decrease airway secretions
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Term
| What muscarinic antagonist is used as a preop agent to reduce airway secretions? |
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Definition
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Term
Tropacamide
Organ system
Application |
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Definition
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Term
| What drugs act as Non depolarizing Neuromuscular Blockers? |
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Definition
-d-Tubocurarine
-Pancuronium
-vecuronium
-Cisatracurium
-Rocuronium
any drug wtih -curarine or -curonium ending |
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Term
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Definition
-non depolarizing neuromuscular blocker
-causes histamine release which can lead to hypotension and bronchospasm |
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Term
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Definition
non depolarizing neuromuscular blocker
-least toxic, most commonly used |
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Term
| What is the only Depolarizing neuromuscular blocker? |
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Definition
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Term
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Definition
| depolarizing neuromuscular blocker |
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