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MSU BMS 110 chapter 9
BMS 110
65
Biology
Undergraduate 1
11/29/2011

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Term
Adaptive Immunity
Definition
a set of immune defenses that are tailored to the particular pathogens that enter the body
Term
Antigen
Definition
a molecule or particle that the immune system recognizes as nonself
Term
B cell
Definition
B lymphocyte. Cells derived from them make antibodies
Term
Basophil
Definition
Circulating white blood cell; factor in inflammation
Term
cytokines
Definition
signaling chemicals released by cells of the immune system
Term
dendritic cell
Definition
phagocytic white blood cell; dendritic cells can mobilize adaptive immunity
Term
eosinophil
Definition
white blood cell that targets large parasites, such as worms
Term
immune system
Definition
a system of interacting white blood cells that defend the body
Term
immunity
Definition
the bodys ability to resist and fight infections
Term
innate immunity
Definition
the body's inborn, general defenses against infection
Term
lymphocytes
Definition
B cells, T cells, and other white blood cells that are active mainly in tissues and organs of the lymphatic system
Term
macrophage
Definition
phagocytic white blood cell in tissue fluid
Term
mast cell
Definition
white blood cell in many tissues; role in inflammation
Term
neutrophil
Definition
phagocyte that follows chemical trails to infected, inflamed or damaged tissues
Term
T Cell
Definition
T lymphocyte. T cells target abnormal body cells, among other roles in adaptive immunity
Term
tonsils
Definition
defense against bacteria and other foreign agents
Term
Right lymphatic duct
Definition
drains the upper portion of the body
Term
thymus gland
Definition
sute where certain T lymphocytes acquire means to chemically recognize specific foreign invaders
Term
Thoracic duct
Definition
Drains most of the body
Term
spleen
Definition
major site of antibody production; disposal site for old red blood cells and foreign debris; site of red blood cell formation in an embryo (filers blood and serves as a reservoir for lymphocytes)
Term
lymph vessels
Definition
return excess tissue fluid and reclaimable solutes to the blood
Term
lymph nodes
Definition
Filter bacteria and many other agents of disease from lymph
Term
Bone Marrow
Definition
Red marrow in some bones is where white blood cells are produced (also red blood cells and platelets)
Term
lymph
Definition
the tissue that moves in lymph vessels
Term
lymph nodes
Definition
organs of the lymphatic system that filter lymph; they are located an intervals along lymph vessels
Term
Lymph vascular system
Definition
lymph capillaries and other vessels of the lymphatic system
Term
lymphatic system
Definition
organs and tissues that return tissue fluid to the cardiovascular system and have roles in defense
Term
lysozyme
Definition
an enzyme that destroys many bacteria
Term
lactobacillus bacteria
Definition
helps maintain low vaginal pH that most bacteria/fungi cant tolerate
Term
complement system
Definition
a set of inactive proteins in blood and tissue fluid; the proteins are activated as part of innate immunity
Term
histamine
Definition
chemical released by mast cells and basophils that helps cause inflammation; it dilates arterioles and makes them leak
Term
membrane attack complex
Definition
structure formed by complement proteins that puntures bacteria, which then die
Term
antibodies
Definition
proteins made by activated B cells that are the cell's antigen receptors
Term
antibody-mediated immune response
Definition
an adaptive immune response in which antibodies are produced against an antigen
Term
B cell receptor
Definition
antigen receptor on a B cell
Term
effector cell
Definition
B or T cell that has been sensitized to an antigen as an adaptive immune response gets underway.  Effectors begin to act as soon as they are sensitized
Term
memory cell
Definition
B or T cell that has been sensitized to an antigen but that remains in reserve and acts in a secondary response
Term
MHC marker
Definition
a self-recognition protein on a body cell
Term
plasma cell
Definition
cell derived from an activated B cell; it produces antibodies that operate in antibody-mediated immunity
Term
T cell receptor
Definition
antigen receptor on a T cell 
Term
antigen-presenting cell
Definition
a cell that processes an antigen in ways that allow a T cell to detect it
Term
cell mediated immune response
Definition
an adaptive immune response mounted by T cells
Term
cytotoxic T cell
Definition
effector T cell that kills body cells infected by a virus or that have been altered by cancer
Term
helper T cell
Definition
effector T cell that stimulates adapative immune responses
Term
immunoglobin
Definition
an antibody
Term
apoptosis
Definition
programmed cell death, which is governed by genes
Term
NK cell
Definition
natual killer cell; a lymphocyte that kills virus-infected cells and some types of cancer cells
Term
active immunity
Definition
immunity that develops after a person recives a vaccine, which stimulates the immune system to produce antibodies against a particular pathogen
Term
immunotherapy
Definition
a clinical therapy that uses immune system cells or substances to treat disease
Term
interferon
Definition
type of cytokine released by cells that infected by a virus.  Uninfected cells may respond by producing substances that prevent the virus from multiplying
Term
monoclonal antibody
Definition
antibodies made in the lab by cells cloned from a single plasma (B) cell
Term
passive immunity
Definition
immunity conferred by injected antibodies to a pathogen. it does not stimulate the recipient's immune system to produce antibodies
Term
vaccine
Definition
a prepared substance that contains an antigen.  most vaccines are made using dead or weakened antigens
Term
allergen
Definition
 a substance that causes an allergic reaction
Term
allergy
Definition
when a normally harmless substance causes an immune response
Term
anaphylactic shock
Definition
a whole-body allergic reaction
Term
autoimmunity
Definition

an immune response unleashed against normal (self) body cells or proteins

Ex. rheumatoid arthritis

type 1 diabetes

systemic lupus erythematosus

Term
immunodeficiency
Definition

weakened of absent immune responses

Ex. servere combined immune deficiency (SCID)

AIDS

Term
immunological tolerance
Definition
the lack of an immune response against normal body cells
Term
endemic disease
Definition
disease that occurs more or less continously
Term
epidemic
Definition
a disease rate that exceeds what would be expected
Term
nosocomial infection
Definition
an infection acquired in a hospital
Term
pandemic
Definition
widespread occurance of an epidemic disease
Term
sporadic disease
Definition
a disease that breaks out irregularly
Term
virulence
Definition
a measure of the likelihood that a pathogen will make its host seriously ill
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