Term
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Definition
osteoid osteoma
osteoblastoma
osteogenic sarcoma |
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Term
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Definition
ewings sarcoma
myeloma
lipoma (fat elements) |
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Term
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Definition
few cells- mature
much stroma
fwer than 5 mitoses
localized |
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Term
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Definition
many cells
immature
much necrosis
little stroma
more than 10 mitoses
blood metastases |
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Term
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Definition
| intracomparmental - within fascial compartment |
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Term
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Definition
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Term
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Definition
| low grade intracompartmental tumor |
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Term
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Definition
| low grade extracompartmental |
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Term
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Definition
aggressive, penetrates bone.
ANy stage with metastis. |
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Term
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Definition
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Term
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Definition
removal of tumor and surrounding tissue.
used for maliganancies, usually |
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Term
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Definition
open biopsy permanant section is 96%. highest
Frozen section is 80% |
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Term
| staging soft tissue malignancies |
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Definition
| grade, depth, size and metastasis. also bone deforming? |
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Term
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Definition
not clearly delineated
breaks through cortex |
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Term
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Definition
sharp border
intact cortex - cortex can balloon out (ABC) |
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Term
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Definition
| chondroblastoma and giant cell tumor |
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Term
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Definition
| chondrosarcoma, osteosarcoma and bone cysts |
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Term
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Definition
ossifying fibroma
ewings sarcoma
myeloma |
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Term
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Definition
LABs: CBC, ESR, CRP, alkaline phos.
Imaging: XR, CT, MRI-softtissue |
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Term
| treatment of malignant tumors |
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Definition
wide excision
radial resection- removing entire compartment
AMPUTATION |
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Term
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Definition
| MC bening lesion of hand and foot |
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Term
| giant cell tumor of tendon sheath |
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Definition
| 2nd MC lesion of hand and foot |
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Term
| giant cell tumor of tendon sheath |
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Definition
golden color due to hemosiderin
Histo: multinucleated giant cells |
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Term
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Definition
| bluish discoloraed mass on hand |
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Term
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Definition
soft and squishy
non-tender
MRI - same color as fat
transforms to liposarcoma |
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Term
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Definition
epidermis gets into dermal layer and proliferates
men, 3-4 decade |
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Term
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Definition
can present as CTS!
painless, volar surface, tinel sign - tap flexor retinaculum
HISTO: antoni A = palisades of tumors cells
Antoni B - minimal cell. BOTH areas will be present in lesion. |
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Term
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Definition
| 50% have mutation of gene "schwannomin" on chrom 22 |
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Term
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Definition
| tumor of fascicles of nerve |
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Term
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Definition
NF-1 - mutation of "neurofibromin" on chrom 17
NF-2 - abn chrom 22 |
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Term
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Definition
VERY painful
lesion under nail
***TRIAD of sxs:
intermittent severe pain
cold intolerance
point tenderness - VERY VERY PAINFUL |
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Term
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Definition
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Term
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Definition
MC benign bone tumor
looks like popcorn on XR, usually of long bones |
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Term
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Definition
Age10-40, pathologic frxs
90% of all bone tumors in hand |
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Term
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Definition
multiple enchondromatosis, nonhereditary
30% malignant transformation to chondrosarcoma |
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Term
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Definition
| soft tissue hemangiomas plus multiple enchondromas |
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Term
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Definition
| has cartilage cap, can have malignant transformation |
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Term
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Definition
benign, soap-bubble appearance on XR
VERY RARE - <20cases |
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Term
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Definition
benign, lytic more frequent than sclerotic
pain relieved by ASA |
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Term
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Definition
| similar to osteoid osteoma but larger! >2cm |
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Term
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Definition
not really a tumor! contains fluid.
in long bones
FALLEN LEAF SIGN - bone fragment from pathologic frx floats in medulla. |
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Term
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Definition
common in hand -metacarpal>phalanx>carpus
common in spine
t(16:17) translocation
Ballooning of cortex |
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Term
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Definition
aggressive, benign (lowgrade malignant)
lytic epiphyseal lesion!!
hand lesion at higher risk for metastasis |
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Term
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Definition
surveillance is mand.
pt must be staged: bone scan, chest XR, CT |
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Term
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Definition
| distal radius lesion is more malignant - 25% metastasize to lung |
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Term
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Definition
>60 yo, prox phalanges and metacarpals!
common in pelvis
slow growing, firm, painful. soft tissue mass.
10%-metastasize |
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Term
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Definition
| bizarre shaped chondrocyte nuclei. NOT normal= malignant |
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Term
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Definition
| Must be removed surgically. does NOT respond to rad or chemo. |
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Term
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Definition
responds to chemo.
lowgrade more common, usually around knee.
Asso. with retinoblastoma (Rb) gene |
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Term
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Definition
rapidly enlarging, painful mass. usually around knee.
packet says in phalanges and metacarpals as well. |
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Term
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Definition
10-20 yo with pelvis lesion.
t(11:22) translocation
small blue round cells |
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Term
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Definition
| painless mass that has been there for a long time, recent growth. |
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Term
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Definition
| Risk factors: rad and herbicides |
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Term
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Definition
treat with wide excision until margins are negative. amputation
Radiation: >5cm
Chemo: highgrade, >10cm, lung metastases |
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Term
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Definition
near joints, mc near carpus
t(x:18) translocation |
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Term
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Definition
| painful with rapid growth |
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Term
| dermatofibrosarcoma protuberans |
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Definition
| horizontal spread, use very wide margins to excise. |
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Term
| Malignant fibrous histiocytoma |
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Definition
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Term
|
Definition
| MC soft tissue sarcoma in children |
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Term
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Definition
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Term
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Definition
| MC malignant primary bone tumor |
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Term
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Definition
| lymphangiosarcoma from chornic lymphedema following mastectomy |
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