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Morphine Sulfate (M.S., MS04
n/a
8
Pharmacology
Undergraduate 1
02/12/2012

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Cards

Term
CLASS
Definition
-Narcotic analgesic
-CNS depressant
Term
ACTIONS
Definition
-CNS Depression - binds to opiate receptors in the brain
-Decreases pain perception and anxiety
-Relaxes respiratory effort
-Produces peripheral vasodialation; thereby decreasing blood return to the heart (preload)
Term
INDICATIONS
Definition
-Chest pain of suspected cardiac origin - pain, anxiety relief; if nitro ineffective
-Moderate to severe pain (burns or isolated extremity trauma)
-Abdominal pain (non-traumatic, suspected kidney stones
-Discomfort secondary to transcutaneous pacing in the awake patient
Term
DOSAGE/ROUTE
Definition
2-20mg in 2mg increments slow IVP; titrated to pain relief and respiratory response
Term
SIDE EFFECTS
Definition
-Respiratory depression and/or arrest
-Decreased LOC
-Transient hypotension
-Nausea/vomiting (stimulation of vomiting center)
Term
CONTRAINDICATIONS
Definition
-Known hypersensitivity to the drug
-Volume depletion
-Suspected ectopic pregnancy, abruptio placenta or abdominal aortic aneurysm
-Unstable vital signs
-Head injury
-MAO inhibitors within 14 days
Term
SPECIAL INFO
Definition
-Narcan will reverse overdose effects
-Monitor B/P, pulse, and respiratory rates between increments
-Utilize caution with patients with COPD, asthma, compromised respirations and the elderly
-Consider utilization of narcan if pt demonstrates respiratory arrest or hypotension post administration (narcan may not reverse hypotension)
-Assess effectiveness of administration with assessment of pain and respiratory status of patient
-Anticipate vomiting
Term
PEDIATRIC NOTE
Definition
-Refer to pediatric drug guide
-0.1-0.1mg/kg slow IVP to a max of 5mg (usual range)
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