• Disturbance in mood as predominant feature
• Options: depressive disorders, bipolar disorders, mood disorder due to a general medical condition and substance-induced mood disorder

• Major depressive
• manic
• mixed
• hypomanic

• major depressive disorder
• dysthymic disorder
• depressive disorder not otherwise specified (NOS)

• bipolar I
• bipolar II
• cyclothymic
• bipolar NOS

One or more Major Depressive Episodes (i.e. at least two weeks of depressed mood of loss of interest accompanied by at least four additional symptoms of depression)

[296.xx]

At least two years of depressed mood for more days than not, accompanied by additional depressive symptoms that do not meet criteria for a Major Depressive Episode

[300.4]

Do not meet the criteria for MDD, Dysthymic, Adjustment w/ Depressed mood, or Adjustment w/ Mixed Anxiety & Depressed Mood 

[311]

One or more Manic or Mixed Episodes, usually accompanied by Major Depressive Episodes

[296.xx]

One or more Major Depressive Episodes accompanied by at least one Hypomanic Episode

[296.89]

At least two years of numerous periods of hypomanic symptoms that do not meet criteria for a Manic Episode and numerous periods of depressive symptoms that do not meet criteria for a Major Depressive Episode

[301.13]

Included for coding disorders with bipolar features that do not meet criteria for any of the specific Bipolar Disorders defined (or bipolar symptoms about which there is inadequate or contradictory information).

[296.80] 

Characterized by a prominent or persistent disturbance in mood that is judged to be a direct physiological consequence of a general medical condition

[293.83]

Characterized by a prominent and persistent disturbance in mood that is judged to be the direct physiological consequence of a drug of abuse, a medication, another somatic treatment for depression, or toxin exposure. 

[29x.xx]

Included for coding disorders with mood symptoms that do not meet the criteria for any specific Mood Disorder and in which it is difficult to choose between Depressive Disorder NOS and Bipolar Disorder NOS

[296.90]

1. First three digits are 296
2. 4th digit is 2 (for one episode) or 3 (for recurrent episodes)
3. 5th digit indicates severity (1 for mild, 2 for moderate, 3 for severe w/o psychotic features, 4 for severe w/ psychotic); if full criteria are not currently met for a MD episode, 5th digit indicates clinical status (5 for partial remission, 6 for full remission); if severity & status are unspecified, 0

1. First three digits are 296
2. 4th digit is 0 for single Manic episode, for recurrent episodes indicates the nature of the current episode (4 for hypo/manic, 6 for mixed, 5 for Major Depressive, 7 for unspecified)
3. 5th digit (except for Bipolar I Hypomanic (always 0)/Unspecified (no 5th digit)] indicates severity if criteria are met for Manic, Mixed or Major Depressive Episode (1 for mild, 2 for moderate, 3 for severe w/o psychotic, 4 for severe w/ psychotic); if full criteria not met, 5 for partial remission, 6 for full remission, 0 for unspecified

Major Depressive Episode - Other Symptoms

1. Changes in appetite, weight, sleep or psychomotor activity
2. Decreased energy
3. Feelings of worthlessness or guilt
4. Difficulty thinking, concentrating or making decisions
5. Recurrent thoughts of death or suicidal ideation, plans, or attempts