Term
| Which of the following is characteristic of malignant tumors? |
|
Definition
|
|
Term
| Gain-of-function mutations in which of the following genes typify colorectal carcinomas? |
|
Definition
|
|
Term
| During metastasis cells may undergo an epithelial-to-mesenchymal transition whereby there is a(n) |
|
Definition
| Loss of cell-cell adhesion |
|
|
Term
| Which of the following promotes angiogenesis? |
|
Definition
|
|
Term
| In females, all the cells in a tumor have the same inactive X chromosome. The reason for this is that |
|
Definition
| all of the cells in a tumor are derived from a single progenitor cell. |
|
|
Term
| Which of the following is a tumor-suppressor gene? |
|
Definition
|
|
Term
| Which of the following is a proto-oncogene? |
|
Definition
|
|
Term
| Germ-line mutations in which of the following has/have been implicated in hereditary cancers? |
|
Definition
|
|
Term
| Hereditary cancers typically possess loss-of-heterozygosity in |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| A loss-of-function mutation in which of the following would have the same effect as a gain-of-function mutation in Ras? |
|
Definition
|
|
Term
| Burkitt's lymphoma results from the overproduction of |
|
Definition
|
|
Term
| Which of the following proteins belong to the control system that regulates cells past a certain point in late G1 (START)? |
|
Definition
|
|
Term
| A gain-of-function mutation in which of the following will bypass restriction point controls? |
|
Definition
|
|
Term
| The human papillomavirus E7 protein inhibits the function of |
|
Definition
|
|
Term
| Micro-RNAs are a new class of oncogenic factors because they function |
|
Definition
| tumor supressors and oncogenes |
|
|
Term
| Direct-acting carcinogens are those that |
|
Definition
| are mainly reactive electrophiles. |
|
|
Term
|
Definition
| contains reverse transcriptase. |
|
|
Term
| Exposure to benzo(a)pyrene is most frequently associated with which type of cancer? |
|
Definition
|
|
Term
| The first line of defense against point mutations is |
|
Definition
|
|
