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molecular bio
exam 2: nucleus
10
Biology
Undergraduate 2
10/16/2008

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Term
True Nucleus
Definition
Exists in eukaryotic cells with primary function of storing DNA and allows for transcription of DNA to RNAs that function as building blocks of cells.
Term
Nuclear Envelope
Definition
Inner Phospholipid Bilayer. Defines nucleus. Outer membrane is continuous with ER.
Term
Nuclear Pores
Definition
100 to 1000 nuclear pores all over. Nuclear Pore Complex: gated transport, standard nucleus traffic cop of proteins that plugs nuclear pores thats shut unless need for transport.
Term
Nuclear Lamina
Definition
Just under inner phospholipid bilayer is strong scaffold made of intermediate filaments. These make up actual structure of nuclear envelope. Breaks down during prophase and proteins that make up nuclear lamina get phosphorolated and fibers get phosphorolated allowing membrane to fall apart.
Term
Outside Nucleus
Definition
Brush pile of intermediate filaments that add to structure.Centrosome outside of nucleus and acts as site where microtubules in cell are built (not part of nucleus, outside).Regulates # microtubules in cell found in close proximity to nucleus creating cage of microtubules around nuclear envelope.
Term
Inside Nucleus
Definition
Chromatin:Packaged DNA making DNA accessible. Heterochromatin:dark area, condensed/not active areas. Euchromatin: light region, actively used.
Term
Genome
Definition
3.2*10^9 base pairs (~30,000 genes). 300 unique genes compared to mice. 2% unique genes compared to chimps. Humans have complex to cause high variety from comparative system genome. Refers to sum total of DNA in cell.
Term
Transcriptome
Definition
Different for different cells. RNA resulting from genome.
Term
Proteome
Definition
Creates unique set of proteins for cell
Term
Nucleolous
Definition
Involved in synthesizing ribosomal RNA and ribosomal precursors.
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