Upon completion of this module you will be able to demonstrate competency in the following outcomes:

• Differentiate various histamine receptors, and understand the effect of drugs on each target.

• Apply PD and PK concepts to efficacy and adverse effects of antihistamines.

• Relate the pharmacology of corticosteroids, NSAIDs, cyclooxygenase-2 inhibitors, and leukotriene inhibitors to eicosanoid pathways.

• Correlate receptor selectivity and onset and duration of action of beta agonists to efficacy and adverse effects.

• Understand mechanism of action and adverse effects of anticholinergics as it relates to chemical structure and drug-receptor relationship.

• Understand the mechanism of action, delivery modes, adverse effects, metabolism, and drug interaction potential of methylxanthines, corticosteroids, cromolyns, leukotriene inhibitors, and anti-IgE antibodies.

• Apply pharmacology concepts to the clinical management of asthma.