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DB - lecture 1 - Model organisms
Sussex university - Year 2 - Developmental Biology-
40
Biology
Graduate
06/07/2013

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Cards

Term
Genetics for fish
Definition
very good
Term
Genetics for worm
Definition
one of the first genomes sequenced
Term
Latin mane for mouse
Definition
Mus musculus
Term
Presentation of frozen embryos available
Definition
Fly
Term
Phyla for chick
Definition
Amniote
Term
Phyla for worm
Definition
Bilaterian
Term
Accessible, cheap, large embryos
Definition
Frog
Term
Latin name for zebra fish
Definition
Danio rerio
Term
Can use gene knockouts and study consequences
Definition
Mouse
Term
Latin name for fruit fly
Definition
Drosophila melanogaster
Term
Genetics for chick
Definition
not good
Term
Phyla for Fly
Definition
Bilaterian
Term
Taught us more about developmental than any other
Definition
Fly
Term
Good over-expression of gene products
Definition
Chick, Frog, Fish
Term
Latin name for worm
Definition
Caenorhabditis elegans
Term
Phyla for mouse
Definition
Mammal
Term
Embryos available in large numbers, transparent and develop outside ovaries
Definition
Fish
Term
Genetics for fly
Definition
Superb
Term
Phyla for fish
Definition
Vertebrate
Term
Can silence gene function using RNAi
Definition
Fly, worm
Term
Robust, easily manipulated
Definition
Frog
Term
Genetics for frog
Definition
Coming along
Term
Excellent imaging of embryos
Definition
Chick and worm
Term
Phyla for Frog
Definition
Tetrapod (amphibian)
Term
Convenient and inexpensive
Definition
Chick
Term
Latin name for chick
Definition
Gallus gallus
Term
Genetics for mouse
Definition
Powerful
Term
Excellent for micro-manipulation
Definition
Chick
Term
Suitable for genetic and experimental manipulation
Definition
Chick
Term
Large collection of mutant lines publicly available
Definition
Fly
Term
Reliable fate maps
Definition
Frog, Worm
Term
Manipulation of gene expression via Gal4 UAS system
Definition
Fly
Term
Latin name for frog
Definition
Xenopus laevis
Term
Loss of function by antisense 'morpholinio' oligonucleotides
Definition
Frog, Fish
Term
Why worm?
Definition
Good imaging of embryo
Can silence gene function by feeding larvae RNAi
Full cell lineage analysis as in no other organism
Presentation of frozen embryos possible
Term
Why mouse?
Definition
Can use gene knockouts and study consequences
Imaging methodologies
Term
Why frog?
Definition
Accessible, cheap, large embryos avaliable
Robust, easily manipulated,
Good for over-expression of gene products
Reliable fate maps
Loss of function by antisense 'morpholino' oligonucleotides
Term
Why fish?
Definition
Embryo available in large numbers, transparent and develop outside
Good for over-expression of gene products
Loss of function by antisense 'morpholino' oligonucleotides
Term
Why chick?
Definition
Convenient and inexpensive
Excellent micromanipulation
Good for over-expression of gene products
Suitable for genetic and experimental manipulation
Term
Why fly?
Definition
Taught us more about developmental than any other
Large collection of mutant strains available to the public
Manipulation of gene expression via Gal4 UAS system
Can silence gene function by RNAi
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