CBC INCLUDES...

[image]

WBC 

WBC DIFFERENTIAL

PLATELET COUNT

HEMAGLOBIN[Hgb]

HEMATOCRIT[Hct]

RBCs

[mean corpuscular volume=MCV]

[mean corpuscular hemaglobin=MCH]

[mean corpuscular hemaglobin conc.=MCHC]

NLMBE

neutrophils

lymphocytes

monocytes

basophils

eosinophils

3,200-11,300cells/mm3

(includes all wbc types)

-inc wbc count

-bac infection

-fungal infctn

-leukemia

-trauma

-stress/emotion/seizures

-dec WBC

-viral infection

-aplastic anemia

-bone marrow depression

[chemotherapy]

[anticonvulsants]

neutrophils 

most common type of wbc

-segs(mature = 36-73%

-Bands(immature)= 3-5%

-fights infctn primarily via phagocytosis('left shift')

-inc 

-bac infctn

-fungal infctn

metabolic disorders

-burns

-stress/emotion/seizures

-dec

-viral infctn

-hepatitis

-mononucleiosis

-septicemia/overwhelming infctn

-chemotherapy

-risk of infctn inc dramatically w/ inc in ANC

-ANC less than 500/mm3 is associated w/ substantial risk of infection

20-40%

2nd most common type

primary response to foreign antigens

-inc

-hepatitis

-mononucleiosis

-Herpes infections, and other viral infctns

- some bac infctns(syphilis)

-leukemia

-multiple myeloma

-dec

-acute infctns

-burns,trauma, lupus,HIV,lymphoma

-0-11%

-formed in bone marrow

-migrate to lymph nodes, spleen, liver, lungs

-mature into Macrophages

-Macrophages scavenge foreign substances

-inc

-recovery phase

-sub acute bac endocarditis(SBE)

-certain infectious diseases

-Leukemia

-lymphoma

-not overly specific for anything

-bone marrow suppressive agents

-severe stress

- 0-8%

-Phagocytic

-Found mostly in the intestinal mucosa and lungs

-Also involved in allergic rxns & immune response

-Have to be done at the same time daily bc they vary based on day time

[0% is normal]

-dec

-adrenal corticoid production

- 0-3%

-phagocytic

-contain heparin,histamine & leukotrienes

-involved in acute hypersensitivity rxns

-inc

-hypersensitivity rxns(food,meds)

-leukemias

-dec

-but 0 % is normal