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MMI Lecture 1
Structure and Function of Bacteria
30
Microbiology
Graduate
01/02/2017

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Cards

Term
The primary structure of a macromolecule determines what?
Definition
Its Function
Term
List the 4 types of Macromolecules that make up a cell wall
Definition
Proteins
Polysaccharides
Phospholipds
Nucleic Acids (DNA/RNA)
Term
What is the primary subunit of a protein?
Definition
amino acids
Term
What is the primary subunit of a polysaccharide?
Definition
sugars (carbohydrates)
Term
What is the primary subunit of a phospholipid?
Definition
fatty acids
Term
What is the primary subunit of a nucleic acid?
Definition
nucleotides
Term
Describe what primary structure means
Definition
It is the sequence in which subunits are put together that determine in the macromolecule
Term
What does the macromolecule protein determine ?
Definition
amino acid sequence determines the properties and function of the protein
Term
What does the nucleic acids determine?
Definition
The genetic code is determined by the specific nucleotide base sequences in chromosomal DNA
Term
What does the polysaccharides determine?
Definition
sequences of sugars in bacterial lipopolysaccharides determines unique cell wall properties for pathaogens
Term
Where in the cell can proteins be found?
Definition
Flagella, pili, cell walls, cytoplasmic membranes, ribosomes, cytoplasm
Term
Where in the cell can polysaccharides be found?
Definition
Polysaccharides sugars (carbohydrates) capsules, inclusions (storage), cell walls
Term
Where in the cell can phospholipids be found?
Definition
membranes
Term
Where in the cell can nucleic acids be found?
Definition
DNA: nucleoid (chromosome), plasmids
rRNA: ribosomes; mRNA, tRNA: cytoplasm
Term
Name the 5 essential structural components of a prokaryotic cell
Definition
A nucleoid (DNA)
Ribosomes
Cell membrane
Cell wall
Surface layer
Term
Name the 3 architectural regions of a prokaryotic cell
Definition
Appendages
Cell envelope
Cytoplasmic region
Term
What is an appendage and give examples
Definition
Attachments to cell surface

Flagella and Pili (or fimbriae)
Term
What does a cell envelope include?
Definition
capsule, cell wall and plasma membrane
Term
What does the cytoplasmic regions contain?
Definition
chromosomes (DNA) and Ribosomes and various inclusions
Term
What is the function and predominant chemical composition of flagella/Pili?
Definition
Swimming movement

Protein
Term
What is the function and predominant chemical composition of sex pilus?
Definition
Stabilizes mating bacteria during DNA transfer by conjugation

Protein
Term
What is the function and predominant chemical composition of common pili or fimbriae?
Definition
Attachment to surfaces; protection against phagotrophic engulfment

Protein
Term
What is the function and predominant chemical composition of Capsules (includes slime layers and glycocalyx)?
Definition
Capsules (includes "slime layers" and glycocalyx) Attachment to surfaces; protection against phagocytic engulfment, occasionally killing or digestion; reserve of nutrients or protection against desiccation Usually polysaccharide; occasionally polypeptide

Usually polysaccharide; occasionally polypeptide
Term
What is the function and predominant chemical composition of Gram positive cell wall?
Definition
Prevents osmotic lysis of cell protoplast and confers rigidity and shape on cells

Peptidoglycan (murein) complexed with teichoic acids
Term
What is the function and predominant chemical composition of Gram negative cell wall?
Definition
Peptidoglycan prevents osmotic lysis and confers rigidity and shape; outer membrane is permeability barrier; associated LPS and proteins have various functions

Peptidoglycan (murein) surrounded by phospholipid protein-lipopolysaccharide "outer membrane"
Term
What is the function and predominant chemical composition of the plasma membrane?
Definition
Permeability barrier; transport of solutes; energy generation; location of numerous enzyme systems

Phospholipid and protein
Term
What is the function and predominant chemical composition of ribosomes?
Definition
Site of translation (protein synthesis)

RNA and Protein
Term
What is the function and predominant chemical composition of Inclusions?
Definition
Often reserves of nutrients; additional specialized functions.

Highly variable; carbohydrate, lipid, protein or inorganic
Term
What is the function and predominant chemical composition of chromosomes?
Definition
Genetic material of cell

DNA
Term
What is the function and predominant chemical composition of the plasmid?
Definition
Extrachromosomal genetic material

DNA
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