Term
| Cellular receptors for microbial antigens found on innate immune cells |
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Definition
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Term
| LPS, peptidoglycan, lipoteichoic acid, viral RNA, fungal mannans |
|
Definition
| Pathogen associated molecular patterns |
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|
Term
| General characteristics of innate immunity |
|
Definition
| No induction period specificity or memory |
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|
Term
| Extensive physical barrier to infection |
|
Definition
| Epithelial lining of portals of entry |
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Term
| Most active phagocytic cell and most abundant circulating WBC |
|
Definition
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|
Term
| Neutrophils, macrophages, dendritic cells, B cells |
|
Definition
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|
Term
| Lysozyme, reactive oxygen intermediates, nitric oxide |
|
Definition
| Microbicidal molecules of phagocytes |
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|
Term
| Enzyme that induces reactive oxygen species |
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Definition
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|
Term
| Pro-inflammatory cytokines that target endothelium |
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Definition
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|
Term
| Adhesion molecules expressed on endothelium that mediate rolling of leukocytes |
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Definition
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|
Term
| Adhesion molecules expressed on leukocyte that mediate tethering of leukocytes |
|
Definition
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|
Term
| Lymphocytes of innate immunity that provide early defense against viral infections |
|
Definition
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|
Term
| Major source of IFNgamma in innate immune system |
|
Definition
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|
Term
| Structural domains found on inhibitory receptors of NK cells |
|
Definition
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|
Term
| Structural domains found on activating receptors of NK cells |
|
Definition
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|
Term
| Intraepithelial lymphocytes that are early sentinels of bacterial infections |
|
Definition
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|
Term
| Activates classical pathway of complement |
|
Definition
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|
Term
| Activate alternative pathway of complement |
|
Definition
| Binding of C3b to microbial surfaces |
|
|
Term
| Activates lectin pathway of complement |
|
Definition
| Terminal mannose residues of microbial glycoproteins |
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|
Term
| Major opsonin generated by complement activation |
|
Definition
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|
Term
| Pro-inflammatory molecules generated by complement activation |
|
Definition
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|
Term
| Polymeric protein complex that lyses microbes |
|
Definition
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|
Term
| Cytokines that activate endothelium |
|
Definition
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|
Term
| Class of cytokines that increase integrin affinity and are chemotacic |
|
Definition
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|
Term
| Cytokines that induces IFNgamma production by NK cells and T cells |
|
Definition
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|
Term
| Cytokine that activates macrophages |
|
Definition
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|
Term
|
Definition
| IFN alpha/beta (Type I IFNs) |
|
|
Term
| Cytokine that down-regulates immune responses |
|
Definition
|
|
Term
| Pro-inflammatory cytokines |
|
Definition
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|
Term
| Inducers of acute phase response |
|
Definition
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|
Term
| Induces proliferation of plasma cells |
|
Definition
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|
Term
| C-reactive protein, mannose-binding lectin and others |
|
Definition
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|
Term
| Signals generated by innate immune reponse to stimulate lymphocytes |
|
Definition
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|
Term
| Substances given with vaccines that stimulate immune reponses |
|
Definition
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|
Term
| Neutrophils, lymphocytes, macrophages (monocytes), eosinophils, basophils |
|
Definition
Cells quantified on a CBC
Never Let Monkeys Eat Bananas! (in decreasing order of quantity) |
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