Term
| Specific immune response, unlike the non-specific immune response, is an _____ to a foreign antigen. |
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Definition
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Term
| Memory produces antibody _____ for antigen causing its production. |
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Definition
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Term
| Higher animals possess _____, or _____, or _____ immune response. |
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Definition
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Term
| Three functions of the immune system: |
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Definition
memory
specificity
distinguish self from non-self |
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Term
| Basic premise of specific immune response: |
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Definition
1st contact -> antibody produced
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v
memory
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v
2nd contact (life lasting antibody) -> antigen destroyed |
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Term
| Specific immune response induced by: |
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Definition
1) actual infection or innoculation (active immunity)
2) artificial transmission of antibody gives temporary protection (passive immunity) |
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Term
| Degree of immunological responsiveness is dependent on: |
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Definition
size of dose
route of entrance
type of agent |
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Term
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Definition
clinical/subclinical infections
injection of antigen (live/killed)
absorption of bacterial produced toxin |
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Term
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Definition
individual comes into contact with antigen producing antibody
individual must be immunocompetent |
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Term
| artificial active immunity |
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Definition
| individual receives inoculation (vaccination) of antigen/toxin which stimulates the production of antibody |
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Term
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Definition
| mother passes Ig on to baby (IgG/IgA) through colostrum found in breast milk |
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Term
| artificial passive immunity |
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Definition
injection of specific antibody (ex: antivenim, antitoxins)
passive immunity is a short-lived, temporary protection which decreases over time; has a half-life; there is no immunologic memory) |
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Term
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Definition
antigen preparation designed to stimulate a favored immune response
use of avirulent/non-pathogenic microorganisms which are unable to cause disease |
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Term
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Definition
inactivated (killed) organism via heat, radiation, chemical
doesn't take well |
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Term
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Definition
weakened form of virus or microorganism
better vaccine because organism may not be completely altered
some vaccines are given in a sequence to provide secondary exposure, which will produce memory |
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Term
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Definition
toxins treated with chemicals
retain their antigenicity |
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Term
| Development of immunocompetent individual: |
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Definition
a) gradually develops through fetal life (genetic)
b) peaks in late teens or early adult life
c) gradual decline with increased age |
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Term
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Definition
| antibody mediated B-cells in bone marrow |
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Term
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Definition
| cell mediated T-cells in thymus |
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