Term
| what is found in the mitochondrial subdomains? |
|
Definition
| cristae, outer membrane, matrix, inner membrane, DNA, and ribosomes |
|
|
Term
| where does the ETC happend |
|
Definition
|
|
Term
| where does the citric acid cycle |
|
Definition
| in the mitochondrial matrix |
|
|
Term
| what must be set up to have chemiosmosis? |
|
Definition
you must have a proton or hydrogen gradient.
voltate gradient
sealed, membrane limit compartment
electron carriers to move electrons from high to low energy states.
couple the process of electron transport to the movement of protons |
|
|
Term
| where is the proton gradient produced and by what mechanism? |
|
Definition
| in the cristae and by proton pumps |
|
|
Term
| what is the proton motive force? |
|
Definition
| this force drives ATP synthesis by the action of ATP synthase |
|
|
Term
| how do mitochondria replicate ? |
|
Definition
|
|
Term
| how do proteins get in from the mitochondria they cannot produce themselves? |
|
Definition
| Translocator Outer and Inner Membrane |
|
|
Term
| what helps attract membrane proteins into the matrix? |
|
Definition
proteins have a signal sequence that must be recognized
proteins bind to a chaperone that uncoils it.
then the tome guiding proteins come in |
|
|
Term
| protein moving into the matrix |
|
Definition
| the inside of the cell is negative and protons are positive. this helps to attract the protons into the cell. |
|
|
Term
| what differentiates mitochondrial DNA from mendelian genetics? |
|
Definition
| the codons are different codes. |
|
|
Term
| why is a mutation in the mitochondrial tRNA so severe? |
|
Definition
it can cause mitochondrial myopathy and ragged red muscle fibers.
high percentage-myoclonic epilepsy |
|
|
Term
| will d loop mutations occur gradually in mitochondria? |
|
Definition
|
|
Term
| what tests would help you notice D loop mutations |
|
Definition
| loss of staining-cytochemical tests |
|
|
Term
| mitochondrial tests would abnormally reveal? |
|
Definition
|
|
Term
| what about D loop mutations |
|
Definition
| no stain of mitochondria will be present |
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