Term
| What is the most common form of pancreatic cancer? |
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Definition
| - Exocrine - starts in the duct = ductal adenocarcinoma |
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Term
| What is the surgery for pancreatic cancer? |
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Definition
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Term
| What is the gold standard for pancreatic cancer? |
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Definition
Chemo: gemcitabine. Can also use 5-FU or Gem + 5-FU
**Metastatic: Folfirinox. |
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Term
| What are risk factors for testicular cancer? |
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Definition
- Family/personal hx of GCT
- Cryptochidism
- Klinefelter syndrome - XXY
- Abnormal testes |
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Term
| What are types of testicular cancer? |
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Definition
Germ Cell tumors: 95%
- Seminoma germ cell - 45%, 4th decade of life. LARGE CELL SHEETS
- NONseminomatous GCTs - 55%, 3rd. 2+ cell types |
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Term
| What are tumor markers for testicular cancer? |
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Definition
- alpha-FP - elevated in NSGCT
- beta-hCG - elevated in both types
- Lactate DH - nonspecific
**Painless testicular mass |
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Term
| What are the standard txs for testicular cancer? |
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Definition
Seminoma: Radiation
Non-seminoma: RPLND
Chemo: Gold standard is Bleomycin + etoposide + cisplatin |
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Term
| What are the risk factors for bladder cancer? |
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Definition
- Smoking - 60% of bladder cancer
- Chemicals in the workplace
- Tx w/ CYCLOPHOSPHAMIDE, radiation |
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Term
| What are the types of bladder cancer? |
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Definition
- Transitional cell carcinoma - 95%
- Squamous cell carcinoma - 3%
- Adenocarcinoma
**75% superficial |
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Term
| What is standard treatment for bladder cancer? |
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Definition
| dd-MVAC = dose dense methotrexate, vinblastine, doxorubicine, cisplatin --> invasive or metastatic. Removal for superficial. |
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Term
| What is Intravesical Bacillus Calmette-Guérin (BCG)? |
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Definition
| For bladder cancer - attenuated live TB for high grade superficial tumors. |
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Term
| What are risk factors for thyroid cancer? |
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Definition
- FEMALE
- Childhood radiation
- Genetic mutation |
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Term
| What are the types of thyroid cancer? |
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Definition
- Papillary - most common, 90%
- Follicular - 10%
- Medullary - high levels of calcitonin
- Anaplastic - spreads rapidly, 1%
**Cold nodule - no uptake of iodine |
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Term
| What is the tx for thyroid cancer? |
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Definition
Radioactive iodine - kill thyroid cancer cells. Systemic therapy not effective.
**Nausea, gastric pain for a few days. Need low iodine diet, STAY 3 FEET AWAY FROM OTHER FOR 5 DAYS |
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