Term
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Definition
Alpha-fetoprotein
Unconjugated Estriol
Human Chorionic Gonadotropin
Inhibin-A |
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Term
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Definition
hormones produced by placenta
high levels can indicate increased risk of Down Syndrome |
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Term
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Definition
protein produced by baby's liver
high level indicates fetal neural tube defect, multiple gestation, or pregnancy further along than believed
low level can indicate risk for Down Syndrome or Trisomy 18 |
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Term
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Definition
protein produced in placenta and in baby's liver
low levels indicate increased risk for Down's |
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Term
First-trimester combined screening |
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Definition
Nuchal translucency
free Beta hCG
PAPP-A |
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Term
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Definition
| increased NT, elevated free BhCG, and reduced PAPP-A suggest this |
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Term
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Definition
| Testing done at 10-14 wks |
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Term
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Definition
| Testing done at 15-20 weeks |
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Term
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Definition
Testing done at 10-12 weeks
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Term
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Definition
| Testing done after 14 weeks |
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Term
Fetal fibronectin testing |
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Definition
| testing done at 24-34 weeks |
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Term
Non stress test - reactive (reassuring) results |
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Definition
| Two accelerations peaking 15 bpm above baseline and lasting for 15 seconds in 20 minutes |
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Term
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Definition
Fetal breathing movements
Body or limb movements
Fetal tone or posture
Cardiotocogram (NST)
amniotic fluid volume
8-10 is reassuring (each is scored 0-2) |
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Term
Ovulatory fertility problem treatments |
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Definition
pharmacologic treatment, ex. clomid
donor oocytes |
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Term
Cervical fertility problem treatments |
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Definition
Therapeutic insemination (THI)
Gamete intrafallopian transfer (GIFT)
IVF |
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Term
Uterine/tubal fertility problem treatment |
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Definition
IVF
Gamete intra fallopian transfer (GIFT)
donor oocytes
gestational carrier |
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Term
Sperm fertility treatment problems |
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Definition
Therapeutic insemination (THI)
IVF
gamete intrafallopian transfer (GIFT)
micromanipulation |
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Term
autosomal dominant disorders |
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Definition
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- Multigenerational
- 50% chance of passing on the gene
- Males and females equally affected
- Varying degrees of presentation
- Ex. Huntington’s chorea |
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Term
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Definition
- Carrier parents
- 25% chance of passing on abnormal gene
- 25% chance of an affected child
- If child is clinically normal, 50% chance child is carrier
- Males and females equally affected
- Ex. Sickle cell disease; most of the diseases tested for with newborn screening tests (enzyme deficiencies)
- This is what newborn screening metabolic tests are looking for |
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Term
X-linked recessive disorders |
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Definition
- No male-to-male transmission
- Only males are affected; women can only be carriers
- 50% chance carrier mother will pass the abnormal gene to sons (affected)
- 50% chance carrier mother will pass the abnormal gene to daughters (carrier)
- Ex. Red-green color blindness; hemophilia (deficiency of factor 8); fragile X syndrome |
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Term
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Definition
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o Have the best, safest, most rewarding birth experience
o Those that stay calm have faster labors |
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