Term
| What are the six most common food poisoning bacteria in the U.S. |
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Definition
Nontyphoid Salmonella
E. coli
Staph. aureus
Shigella spp.
Clostridium perfringens
Campylobacter jejuni |
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Term
| Describe the disease manifestation of Shigella. (Symptoms, is it invasive/noninvasive, method of pathogenesis, method of transmission) |
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Definition
Symptoms: dysentery (remember it's one of the major Enterobacteriaceae for healthy people, which all cause some form of diarrhea).
It's invasive (in the colon) so you get fecal leukocytes.
Method of pathogenesis is via Shiga toxin.
Method of Transmission: fecal oral. |
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Term
| How does Shiga toxin (STX) do its thing? Which tissues does it work in? |
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Definition
It inactivates host ribosomes to stop protein synthesis.
Kidney cells are sensitive, as well as those in the intestines. |
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Term
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Definition
| Some strains of Shigella but mostly EHEC. |
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Term
| Is Shigella intra or extracellular? |
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Definition
| facultative intracellular |
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Term
| Name all of the encapsulated organisms (not viruses) |
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Definition
C. neoformans (fungus)
S. pneumoniae (gram +)
S. pyogenes (gram +)
B. anthracis (gram +)
H. influenzae b (gram -)
P. aeruginosa (gram -)
S. typhi (gram -)
K. pneumoniae (gram -)
E. coli K1 (gram -)
N. meningitidis (gram -) |
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Term
| Describe Salmonella: transmission route, invasive/noninvase |
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Definition
Transmission route: ingestion
Invasive, so you'll see fecal leukocytes |
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Term
| What is an invasive pathogen? |
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Definition
| One that penetrates the epithelium by itself. |
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Term
| Influenza Virus: site of invasion |
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Definition
| respiratory epithelium. Stops at epithelium (b/c influenza viruses only bud from the apical surfaces of epithelium). |
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Term
| Rhinovirus: site of invasion |
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Definition
| Repiratory epithelium (stops at epithelium b/c it replicates best at lower temps that are not present in deeper tissue) |
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Term
| Shigella spp.: Site of invasion |
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Definition
| GI tract epithelium (stops at epithelium) |
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Term
| Rotavirus: site of invasion |
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Definition
| GI tract epithelium (stops at epithelium) |
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Term
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Definition
| epithelia of skin or urogenital tract (depending on which type of HPV). Stop at epithelium. |
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Term
| Chlamydia spp.: site of invasion |
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Definition
| Urogenital tract epithelium. Stops at epithelium |
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Term
| Salmonella typhi: site of invasion |
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Definition
| GI tract epithelia (invades and then keeps going (disseminates) |
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Term
| Poliovirus: site of invasion |
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Definition
| GI tract epithelia (invades and then keeps going) |
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Term
| HSV (1 and 2): site of invasion |
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Definition
| urogenital tract epithelia (invades and then keeps going) |
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Term
| Treponema pallidum: site of invasion |
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Definition
| urogenital tract epithelia (invades and then keeps going) |
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Term
| Staph aureus: site of invasion |
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Definition
| skin epithelia (invades and then keeps going) |
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Term
| Measles virus: site of invasion |
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Definition
| respiratory tract epithelia (invades and then keeps going, disseminates, because it is bloodborne) |
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Term
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Definition
| respiratory tract epithelia (invades and then keeps going) |
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Term
| Mycobacterium tuberculosis: site of invasion |
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Definition
| respiratory tract epithelia (invades and then keeps going) |
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Term
| Yersinia: site of invasion |
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Definition
| GI tract epithelia: invades and then keeps going to the subepithelia |
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Term
| Nontyphoid salmonella: site of invasion. |
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Definition
| GI tract epithelia (stops at subepithelial tissue) |
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Term
| What does inflammation in Gram neg bacteria often involve? |
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Definition
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Term
| What is the reservoir for Shigella spp.? |
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Definition
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Term
| How is Shigella spp. transmitted? |
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Definition
| fecal oral, human to human transmission |
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Term
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Definition
| can range from mild bloodless diarrhea to dysentery and fever with blood in stool. Can also be asymptomatic carriers. |
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Term
| Do you have fecal leukocytes with Shigella? |
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Definition
| Yes, it is an invasive disease. |
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