Term
| A method of isolation in which a diluted microbial sample is deposited on an agar plate and spread uniformly across the surface? |
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Definition
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Term
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Definition
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Term
| What are 3 reasons for performing antibiotic sensitivity tests? |
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Definition
1. Physicians need to know which drugs are the most effective against a specific organism as well as the dosage level.
2. Method of determining if microorganisms are developing resistance to particular antibiotics.
3. Information about the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). |
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Term
| Kill or inhibit microbial growth? |
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Definition
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Term
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Definition
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Term
| Typically applied to living tissues? |
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Definition
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Term
| _______ are synthesized by microorganisms in order to compete with other other microbes for resources. |
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Definition
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Term
| Typically administered internally, toxic to bacterial cells and sometimes humans? |
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Definition
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Term
| What are Erythromycin, Penicillin, and Ampicillin examples of? |
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Definition
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Term
| What are 70% alcohol, betadine, and Neosporin examples of? |
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Definition
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Term
| Applied to inanimate objects in order to kill microbes? |
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Definition
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Term
| What are Phenol, Amphyll, and bleach examples of? |
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Definition
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Term
| Synthetically produce substances that are administered internally in order to kill microbes? |
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Definition
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Term
| Inhibit the growth of bacteria? |
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Definition
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Term
| Reduces the amount of bacteria to a safe level? |
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Definition
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Term
| What is hand soap a example of? |
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Definition
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Term
| Classification of Antibiotics and Chemotherapeutic agents is based on what? |
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Definition
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Term
| What B vitamin is a required growth factor for bacteria? |
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Definition
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Term
| Precursor molecule in the folic acid biosynthesis pathway? |
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Definition
| Para-aminobenzoic acid (PABA) |
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Term
| Functions as a substrate analog of PABA and thus causes a defect in the biosynthetic pathway of folic acid? |
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Definition
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Term
| Typically used in the treatment of urinary tract infections (UTIs)? |
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Definition
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Term
| Peptidoglycan is a component of the (prokaryotic/eukaryotic) cell envelope. |
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Definition
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Term
| If synthesis of (PABA/peptidoglycan) is interrupted or prevented, then the cell envelope becomes weak and is susceptible to lysis. |
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Definition
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Term
| Penicllins are inhibitors of what? |
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Definition
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Term
| Cephalosporins are inhibitors of what? |
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Definition
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Term
| Bactrin or Triple sulfa are inhibitors of what? |
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Definition
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Term
| What enzyme provides resistance to peptidoglycan synthesis? |
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Definition
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Term
| Selectively toxic because they inhibit protein synthesis on ribosomal 50S or 30S subunits which from the 70S ribosome of prokaryotes? |
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Definition
| Inhibitors of protein synthesis |
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Term
| Changes shape of 30S r-RNA and causes m-RNA to be read incorrectly? |
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Definition
| Aminoglycosides (streptomycin, neomycin, and gentamycin) |
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Term
| Interferes with positive RNA anticodon reading of the m-RNA codon? |
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Definition
| Tetracyclines (tetracycline) |
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Term
| Binds to 50S r-RNA and prevents movement along m-RNA? |
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Definition
| Macrolides (erythromycin) |
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Term
| Disrupt the lipids present in the cell wall creating pores making the cell leaky? |
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Definition
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Term
| Alters outer membrane due to negatively charged LPS and positive amino groups? |
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Definition
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Term
| Inhibits fatty acid synthesis by binding to enoyl-acyl carrier protein reductase? |
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Definition
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Term
| Target the enzyme DNA gyrase, which unwinds positively super-coiled DNA during DNA replication? |
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Definition
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Term
| Also known as the disc diffusion assay? |
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Definition
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Term
| The sensitivity of bacteria to a specific antimicrobial agent? |
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Definition
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Term
| Lowest concentration of an antimicrobial that will inhibit the visible growth of a microorganism after overnight incubation? |
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Definition
| Minimum inhibitory concentration (MIC) |
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